How human leukocytes track down and destroy pathogens: lessons learned from the model organism Dictyostelium discoideum

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Immunologic research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12026-008-8056-7PMID 18827980
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chemotaxis, chemokine receptors and human disease.

  2008cited by this paper
• An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis.

  2008cited by this paper
• Engulfment of apoptotic cells: signals for a good meal

  2007cited by this paper
• Locally controlled inhibitory mechanisms are involved in eukaryotic GPCR-mediated chemosensing

  2007influential reference
• A vesicle surface tyrosine kinase regulates phagosome maturation

  2007cited by this paper
• Key Role of Local Regulation in Chemosensing Revealed by a New Molecular Interaction-Based Modeling Method

  2006cited by this paper
• Moving toward understanding eukaryotic chemotaxis.

  2006influential reference
• Lipid metabolism and dynamics during phagocytosis.

  2006cited by this paper
• Dissociation of Recruitment and Activation of the Small G-protein Rac during Fcγ Receptor-mediated Phagocytosis*

  2006cited by this paper
• Phagocytosis: elegant complexity.

  2005cited by this paper
• Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium.

  2004influential reference
• The engulfment process of programmed cell death in caenorhabditis elegans.

  2004cited by this paper
• Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

  2004cited by this paper
• Regulation of Phagosome Maturation by Signals from Toll-Like Receptors

  2004cited by this paper
• Cellular motility driven by assembly and disassembly of actin filaments.

  2003cited by this paper
• ReviewCellular Motility Driven by Assembly and Disassembly of Actin Filaments to decipher

  2003cited by this paper
• International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

  2003cited by this paper
• Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens

  2003cited by this paper
• Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils.

  2003cited by this paper
• Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis.

  2002cited by this paper
• Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

  2002cited by this paper
• Temporal and spatial regulation of chemotaxis.

  2002cited by this paper
• International Union of Pharmacology. XXX. Update on Chemokine Receptor Nomenclature

  2002cited by this paper
• Regulation of phagocytosis and endo-phagosomal trafficking pathways in Dictyostelium discoideum.

  2001cited by this paper
• The Phagosome Proteome

  2001cited by this paper
• The Phagosome Proteome: Insight into Phagosome Functions

  2001cited by this paper
• Plagiarism and pathogenesis: common themes in actin remodeling.

  2001cited by this paper
• Localization of the G Protein βγ Complex in Living Cells During Chemotaxis

  2000influential reference
• Localization of the G protein betagamma complex in living cells during chemotaxis.

  2000cited by this paper
• Polarization of chemoattractant receptor signaling during neutrophil chemotaxis.

  2000influential reference
• A cell's sense of direction.

  1999influential reference
• Desensitization of G-protein-coupled Receptors

  1999cited by this paper
• Mechanisms of phagocytosis in macrophages.

  1999cited by this paper
• AGONIST-INDUCED PHOSPHORYLATION OF THE CHEMOATTRACTANT RECEPTOR cAR1 LOWERS ITS INTRINSIC AFFINITY FOR cAMP*

  1999cited by this paper
• G protein signaling events are activated at the leading edge of chemotactic cells.

  1998influential reference
• G Protein β Subunit–null Mutants Are Impaired in Phagocytosis and Chemotaxis Due to Inappropriate Regulation of the Actin Cytoskeleton

  1998cited by this paper
• Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis

  1997cited by this paper
• Dynamic Distribution of Chemoattractant Receptors in Living Cells During Chemotaxis and Persistent Stimulation

  1997cited by this paper
• Desensitization of G protein-coupled receptors.

  1996cited by this paper
• A chemoattractant receptor controls development in Dictyostelium discoideum.

  1988cited by this paper
• Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium.

  1988cited by this paper
• Quantification of endocytosis-derived membrane traffic.

  1985cited by this paper
• The acrasin activity of adenosine-3',5'-cyclic phosphate.

  1967cited by this paper

• The gold nanoparticle-lipid membrane synergy for nanomedical applications.

  2025cites this paper
• Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis

  2024cites this paper
• Engineering white blood cell membrane-camouflaged nanocarriers for inflammation-related therapeutics.

  2023cites this paper
• Centrosome Positioning in Migrating Dictyostelium Cells

  2022cites this paper
• White Blood Cell Membrane‐Coated Nanoparticles: Recent Development and Medical Applications

  2021cites this paper
• Supported bilayer membranes for reducing cell adhesion in microfluidic devices.

  2021cites this paper
• Chemotaxis: Under Agarose Assay.

  2021cites this paper
• ELMO2 association with Gαi2 regulates pancreatic cancer cell chemotaxis and metastasis

  2020cites this paper
• Adaptation of Living Systems.

  2018cites this paper
• MetReS, an Efficient Database for Genomic Applications

  2017cites this paper
• G Protein Coupled Receptors-Mediated Chemotaxis in theModel Organism Dictyostelium Discoideum and Neutrophils

  2017cites this paper
• Alternative Eukaryotic Expression Systems for the Production of Proteins and Protein Complexes.

  2016cites this paper
• Advanced Technologies for Protein Complex Production and Characterization

  2016cites this paper
• Functional characterization of iron transporters Nramp 1 and Nramp 2 from Dictyostelium discoideum : a model of cellular iron homeostasis

  2016cites this paper
• Chemotaxis: Under Agarose Assay.

  2016cites this paper
• Identification of anti-infective compounds using amoebae

  2016cites this paper
• Anticancer and Apoptosis Inducing Effect of Methanolic Extract of Leaves and Rhizomes of Curcuma amada Roxb in Breast Cancer Cell Lines

  2014cites this paper
• Chemotaxis and cell migration

  2014cites this paper
• The Diaphanous-related formin dDia1 is required for highly directional phototaxis and formation of properly sized fruiting bodies in Dictyostelium.

  2014cites this paper
• Database Constraints Applied to Metabolic Pathway Reconstruction Tools

  2014cites this paper
• Effects of synthetic peptides on the inflammatory response and their therapeutic potential.

  2013cites this paper
• Effects of Synthetic Peptides on the Inflammatory Response and their Therapeutic Potential

  2013cites this paper
• Investigating the effect of emetic and aversive compounds on Dictyostelium identifies a novel non-sentient model for bitter tastant research

  2013cites this paper
• Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay

  2013cites this paper
• A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum

  2013cites this paper
• Dictyostelium host response to legionella infection: strategies and assays.

  2013cites this paper
• Cell Migration: Regulation of cytoskeleton by Rap1 in Dictyostelium discoideum

  2012influential citation
• Diverse Sensitivity Thresholds in Dynamic Signaling Responses by Social Amoebae

  2012cites this paper
• Involvement of Rab6 in the regulation of phagocytosis against virus infection in invertebrates.

  2012cites this paper
• A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex

  2012cites this paper
• Signaling network from GPCR to the actin cytoskeleton during chemotaxis

  2012cites this paper
• Nhe1 Is Essential for Potassium but Not Calcium Facilitation of Cell Motility and the Monovalent Cation Requirement for Chemotactic Orientation in Dictyostelium discoideum

  2011cites this paper
• Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease.

  2011cites this paper
• Chemotaxis in cancer

  2011cites this paper
• Autophagy in Inflammatory Diseases

  2011cites this paper
• Sind Aquaporine an der Zellwanderung beteiligt

  2011cites this paper
• Saccharomyces cerevisiae as a Model Organism: A Comparative Study

  2011cites this paper
• The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens

  2011cites this paper
• The ageing immune system and its clinical implications

  2011cites this paper
• Investigating the Effect of Emetic Compounds on Chemotaxis in Dictyostelium Identifies a Non-Sentient Model for Bitter and Hot Tastant Research

  2011cites this paper
• Tyrosine Phosphorylation-Mediated Signaling Pathways in Dictyostelium

  2011cites this paper
• Drosophila cellular immunity: a story of migration and adhesion

  2011cites this paper
• Synthesis and biological activity of peptides equivalent to the IP22 repeat motif found in proteins from Dictyostelium and Mimivirus.

  2010cites this paper
• Coupling Mechanism of a GPCR and a Heterotrimeric G Protein During Chemoattractant Gradient Sensing in Dictyostelium

  2010cites this paper
• A dual protease inhibitor/receptor antagonist with therapeutic implications for chronic inflammatory lung diseases

  2010cites this paper
• Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila

  2010cites this paper
• A Coronin7 Homolog with Functions in Actin-driven Processes*

  2010cites this paper
• Ca2+ chemotaxis in Dictyostelium discoideum

  2010cites this paper
• Autophagy in Dictyostelium: Genes and pathways, cell death and infection

  2010cites this paper
• [Dictyostelium. A social amoeba as a model organism].

  2010cites this paper
• Involvement of Src Family Tyrosine Kinase in Apoptosis of Human Neutrophils Induced by Protozoan Parasite Entamoeba histolytica

  2010cites this paper
• Chemotaxis: new role for Ras revealed

  2010cites this paper
• Photosynthesis-dependent Ca2+ influx and functional diversity between phospholipases in the formation of cell polarity in migrating cells of red algae

  2009cites this paper
• The Elmo family forms an ancient group of actin-regulating proteins

  2009cites this paper
• Dictyostelium discoideum—a model for many reasons

  2009cites this paper
• between phospholipases in the formation of cell polarity in red algal migrating cells

  2009cites this paper
• Clonal analysis of growth behaviors during "Drosophila" larval tracheal development

  2009cites this paper
• Dendritic cell altered states: what role for calcium?

  2009cites this paper
• Photosynthesis-dependent Ca 2+ Influx and Functional Diversity between Phospholipases in the Formation of Cell Polarity in Red Algal Migrating Cells Photosynthesis-dependent Extracellular Ca 2+ Influx in Cell Polarity Establishment Functional Diversity between Phospholipases C and D in Monospore Mig

  year unknowncites this paper