LyP-1-conjugated doxorubicin-loaded liposomes suppress lymphatic metastasis by inhibiting lymph node metastases and destroying tumor lymphatics

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Nanotechnology

• Publication date

  2011-10-14

• Fields of study

  Materials Science, Medicine, Physics

• Identifiers
  DOI 10.1088/0957-4484/22/41/415103PMID 21914940
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Erythropoietin induces lymph node lymphangiogenesis and lymph node tumor metastasis.

  2011cited by this paper
• Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer

  2011cited by this paper
• Imaging tumor-induced sentinel lymph node lymphangiogenesis with LyP-1 peptide

  2011cited by this paper
• Therapeutic ultrasonic microbubbles carrying paclitaxel and LyP-1 peptide: preparation, characterization and application to ultrasound-assisted chemotherapy in breast cancer cells.

  2011cited by this paper
• Deguelin—An inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor‐D in lung tumor model

  2010cited by this paper
• Endostatin inhibits tumour lymphangiogenesis and lymphatic metastasis via cell surface nucleolin on lymphangiogenic endothelial cells

  2010cited by this paper
• LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors.

  2010cited by this paper
• Lymphangiogenesis and lymphatic metastasis in breast cancer.

  2010cited by this paper
• Targeting of albumin-embedded paclitaxel nanoparticles to tumors.

  2009cited by this paper
• Tumor lymphangiogenesis and melanoma metastasis

  2008cited by this paper
• In vivo tumor cell targeting with "click" nanoparticles.

  2008cited by this paper
• Peptide Targeting of Tumor Lymph Vessels

  2008cited by this paper
• Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma.

  2008cited by this paper
• Lymph node mapping in the mouse.

  2008cited by this paper
• Tumor targeting of baculovirus displaying a lymphatic homing peptide

  2008cited by this paper
• Microvessel Density and Clinicopathologic Characteristics in Hepatocellular Carcinoma With and Without Cirrhosis

  2007cited by this paper
• Anti‐VEGF‐A therapy reduces lymphatic vessel density and expression of VEGFR‐3 in an orthotopic breast tumor model

  2007cited by this paper
• Enhanced Baculovirus-Mediated Transduction of Human Cancer Cells by Tumor-Homing Peptides

  2006cited by this paper
• Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2.

  2006cited by this paper
• Tumor lymphangiogenesis and metastatic spread—New players begin to emerge

  2006cited by this paper
• VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

  2005cited by this paper
• Lymphangiogenesis in development and human disease

  2005cited by this paper
• Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells.

  2004cited by this paper
• A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets.

  2004cited by this paper
• A tumor-homing peptide with a targeting specificity related to lymphatic vessels

  2002cited by this paper
• Prevention and treatment of lymphatic metastasis by antilymphangiogenic therapy.

  2002cited by this paper
• Targeting Lymphatic Metastasis

  2002cited by this paper
• Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

  2002cited by this paper
• Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

  2001cited by this paper
• Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3

  2001cited by this paper
• Liposomes to target the lymphatics by subcutaneous administration.

  2001cited by this paper
• Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases.

  1993cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper
• Iodine Oxidation of S‐Trityl‐ and S‐Acetamidomethyl‐cysteine‐peptides Containing Tryptophan: Conditions Leading to the Formation of Tryptophan‐2‐thioethers

  1980cited by this paper
• The synthesis of cystine peptides by iodine oxidation of s trityl cysteine and s acetamidomethyl cysteine peptides

  1980cited by this paper

• Tumor Targeting with Peptide-Drug Conjugates: Showcasing Key Progress and Hurdles.

  2026cites this paper
• Lymphatic metastasis in pancreatic cancer: from bedside to bench and back

  2025cites this paper
• Advances in functional lipid nanoparticles: from drug delivery platforms to clinical applications

  2024cites this paper
• Nano-fluorescence imaging: advancing lymphatic disease diagnosis and monitoring

  2024cites this paper
• The emerging roles of long noncoding RNAs in lymphatic vascular development and disease

  2023cites this paper
• Biocompatible Tantalum Nanoparticles as Radiosensitizers for Enhancing Therapy Efficacy in Primary Tumor and Metastatic Sentinel Lymph Nodes.

  2022cites this paper
• Lymphatic targeting for therapeutic application using nanoparticulate systems

  2022cites this paper
• Selenium-containing Peptides and their Biological Applications.

  2022cites this paper
• Emerging Nanotherapeutic Approaches to Overcome Drug Resistance in Cancers with Update on Clinical Trials

  2022cites this paper
• The lymphatic vasculature: An active and dynamic player in cancer progression

  2021cites this paper
• Progression of Metastasis through Lymphatic System

  2021cites this paper
• Preparation and Evaluation of Integrin Receptor-Mediated Targeting Drug Liposomes

  2021cites this paper
• Human Microcirculation‐on‐Chip Models in Cancer Research: Key Integration of Lymphatic and Blood Vasculatures

  2020cites this paper
• Lymphatic targeting by albumin-hitchhiking: Applications and optimisation.

  2020cites this paper
• Cancer Nanomedicine: Strategies to Enhance Tumor Delivery and Immunotherapy

  2020cites this paper
• Tumor-targeted Strategies

  2020cites this paper
• Design and in vitro evaluation of solid SEDDS for breast cancer therapy

  2020cites this paper
• Nano-therapeutics for modulating the tumour microenvironment: Design, development, and clinical translation.

  2020cites this paper
• Cancer-Targeted PEDF-DNA Therapy for Metastatic Colorectal Cancer.

  2019cites this paper
• Targeting Tumor Endothelial Cells with Nanoparticles

  2019cites this paper
• Recent progress in LyP-1-based strategies for targeted imaging and therapy

  2019influential citation
• Drug formulation and nanomedicine approaches to targeting lymphatic cancer metastases.

  2019cites this paper
• Efficacy of a novel LyP‐1‐containing self‐microemulsifying drug delivery system (SMEDDS) for active targeting to breast cancer

  2019cites this paper
• Engineered nanomedicines with enhanced tumor penetration

  2019cites this paper
• A targeted nanoplatform co-delivering chemotherapeutic and antiangiogenic drugs as a tool to reverse multidrug resistance in breast cancer.

  2018cites this paper
• Multiple functionalized carbon quantum dots for targeting glioma and tissue imaging

  2018cites this paper
• Molecular dynamics, thermodynamic, and mutational binding studies for tumor-specific LyP-1 in complex with p32

  2018cites this paper
• Lymph node metastases: importance of detection and treatment strategies

  2018cites this paper
• LyP-1-conjugated Fe3O4 nanoparticles suppress tumor growth by magnetic induction hyperthermia

  2018cites this paper
• Tumor penetrating peptides for improved drug delivery

  2017cites this paper
• Self-Assembled Tumor-Penetrating Peptide-Modified Poly(l-γ-glutamylglutamine)-Paclitaxel Nanoparticles Based on Hydrophobic Interaction for the Treatment of Glioblastoma.

  2017cites this paper
• Structure Reconstruction of LyP-1: Lc(LyP-1) Coupling by Amide Bond Inspires the Brain Metastatic Tumor Targeted Drug Delivery.

  2017cites this paper
• Seek & Destroy, use of targeting peptides for cancer detection and drug delivery.

  2017cites this paper
• Nanoformulations: A lucrative tool for protein delivery in cancer therapy

  2016cites this paper
• Peptides to Target Tumor Vasculature and Lymphatics for Improved Anti-Angiogenesis Therapy.

  2016cites this paper
• Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug

  2016cites this paper
• Lymphatic Targeting of Nanosystems for Anticancer Drug Therapy.

  2016cites this paper
• Targeted Delivery of Bleomycin: A Comprehensive Anticancer Review.

  2016cites this paper
• Nanocarriers Conjugated with Cell Penetrating Peptides: New Trojan Horses by Modern Ulysses.

  2016cites this paper
• Lymph Nodes and Cancer Metastasis: New Perspectives on the Role of Intranodal Lymphatic Sinuses

  2016cites this paper
• Poly(l-γ-glutamylglutamine) Polymer Enhances Doxorubicin Accumulation in Multidrug Resistant Breast Cancer Cells

  2016cites this paper
• Selective interaction of PEGylated polyglutamic acid nanocapsules with cancer cells in a 3D model of a metastatic lymph node

  2016cites this paper
• Drug Delivery to the Lymphatic System

  2016cites this paper
• Strategies of overcoming the physiological barriers for tumor-targeted nano-sized drug delivery systems.

  2015cites this paper
• Nanomedicine and cancer immunotherapy – targeting immunosuppressive cells

  2015cites this paper
• Tumor-penetrating peptide mediation: an effective strategy for improving the transport of liposomes in tumor tissue.

  2014cites this paper
• Targeted Liposomes and Micelles as Carriers for Cancer Therapy

  2014cites this paper
• Perspectives and Challenges of Cell-Penetrating Peptides in Effective siRNA Delivery

  2014cites this paper
• Liposomal delivery and polyethylene glycol-liposomal oxaliplatin for the treatment of colorectal cancer (Review)

  2014cites this paper
• Tumor homing peptides as molecular probes for cancer therapeutics, diagnostics and theranostics.

  2014cites this paper
• Recent advances in lymphatic targeted drug delivery system for tumor metastasis

  2014influential citation
• Tumor-penetrating peptide functionalization enhances the anti-glioblastoma effect of doxorubicin liposomes

  2013cites this paper
• Biological rationale for the design of polymeric anti-cancer nanomedicines

  2013cites this paper
• Polymeric micelles for enhanced lymphatic drug delivery to treat metastatic tumors.

  2013cites this paper
• Nanopreparations to overcome multidrug resistance in cancer.

  2013cites this paper
• Tumor-targeted liposomal drug delivery mediated by a diseleno bond-stabilized cyclic peptide

  2013cites this paper
• Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting

  2013cites this paper
• Peptide Targeted Lipid Nanoparticles for Anticancer Drug Delivery

  2012cites this paper
• Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors.

  2012cites this paper
• Update March 2012

  2012cites this paper