Kinetics of GADD45α, TP53 and CASP3 gene expression in the rat lens in vivo in response to exposure to double threshold dose of UV-B radiation.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Experimental Eye Research

• Publication date

  2012-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.exer.2012.02.003PMID 22559303
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A new universal rat restrainer for ophthalmic research

  2011cited by this paper
• Evolution of damage in the lens after in vivo close to threshold exposure to UV-B radiation: cytomorphological study of apoptosis.

  2010cited by this paper
• DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers

  2008cited by this paper
• Gadd45 in stress signaling

  2008cited by this paper
• Apoptosis: A Review of Programmed Cell Death

  2007cited by this paper
• p53 expression and apoptosis in the lens after ultraviolet radiation exposure.

  2007cited by this paper
• Global data on visual impairment in the year 2002.

  2004cited by this paper
• UV Induces GADD45 in a p53-Dependent and -Independent Manner in Human Keratinocytes

  2003cited by this paper
• Prospects for antiapoptotic drug therapy of neurodegenerative diseases.

  2003cited by this paper
• Comparison of immunohistochemistry for activated caspase‐3 and cleaved cytokeratin 18 with the TUNEL method for quantification of apoptosis in histological sections of PC‐3 subcutaneous xenografts

  2003cited by this paper
• Toxicity of ultraviolet radiation exposure to the lens expressed by maximum tolerable dose.

  2002cited by this paper
• Improved Detection of Apoptotic Cells in Archival Paraffin Sections: Immunohistochemistry Using Antibodies to Cleaved Caspase 3

  2002cited by this paper
• GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

  2002cited by this paper
• Mechanisms of p53-dependent apoptosis.

  2001cited by this paper
• p53-dependent apoptosis pathways.

  2001cited by this paper
• Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency.

  2001cited by this paper
• Viewing apoptosis through a ‘TUNEL’

  2001cited by this paper
• Influence of exposure time for UV radiation-induced cataract.

  2000cited by this paper
• Repair in the rat lens after threshold ultraviolet radiation injury.

  2000cited by this paper
• Expression of breast cancer resistance protein in blast cells from patients with acute leukemia.

  2000cited by this paper
• Light exposure and the risk of cortical, nuclear, and posterior subcapsular cataracts: the Pathologies Oculaires Liées à l'Age (POLA) study.

  2000cited by this paper
• Expression of breast cancer resistance protein in blast cells from patients with acute leukemia

  2000cited by this paper
• Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

  1998cited by this paper
• Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding

  1998cited by this paper
• Apoptosis in the rat lens after in vivo threshold dose ultraviolet irradiation.

  1998cited by this paper
• p53, the Cellular Gatekeeper Review for Growth and Division

  1997cited by this paper
• Abrogation of p53 Function Affects gadd Gene Responses to DNA Base-Damaging Agents and Starvation

  1996cited by this paper
• Apoptin, a protein derived from chicken anemia virus, induces p53-independent apoptosis in human osteosarcoma cells.

  1995cited by this paper
• Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals

  1995cited by this paper
• In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

  1995cited by this paper
• Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

  1995cited by this paper
• Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

  1994cited by this paper
• p53-Dependent apoptosis in the absence of transcriptional activation of p53-target genes

  1994cited by this paper
• Thymocyte apoptosis induced by p53-dependent and independent pathways

  1993cited by this paper
• Ultraviolet light exposure and lens opacities: the Beaver Dam Eye Study.

  1992cited by this paper
• Experimental cataract induced by ultraviolet radiation.

  1990cited by this paper
• Experimental cataract induced by ultraviolet radiation.

  1990cited by this paper
• Unscheduled DNA synthesis in lens epithelium after in vivo exposure to UV radiation in the 300 nm wavelength region

  1986cited by this paper
• An effect of ultraviolet light on RNA and protein synthesis in nondividing human diploid fibroblasts.

  1979cited by this paper
• Ocular effects of ultraviolet radiation from 295 to 365 nm.

  1977cited by this paper
• Radiation: Studies of Mouse Cells Lacking P53-mediated Dna Repair Responses to Uv

  year unknowncited by this paper

• Expression of active caspase 3 in the rat lens after in vivo exposure to subthreshold dose of UVR-B

  2024cites this paper
• A grape-supplemented diet prevented ultraviolet (UV) radiation-induced cataract by regulating Nrf2 and XIAP pathways

  2024cites this paper
• Upregulation of EphA2 is associated with apoptosis in response to H2O2 and UV radiation-induced cataracts.

  2023cites this paper
• Estimation of the Variance Components in TP53 mRNA Expression in the Rat Lens after in vivo Exposure to Ultraviolet Radiation B

  2023cites this paper
• Comparative proteomics in captive giant pandas to identify proteins involved in age-related cataract formation

  2023cites this paper
• Cellular localization of FOXO3 determines its role in cataractogenesis.

  2023cites this paper
• RNA-Seq analysis in giant pandas reveals the differential expression of multiple genes involved in cataract formation

  2021cites this paper
• Genome-wide analysis of methylation in giant pandas with cataract by methylation-dependent restriction-site associated DNA sequencing (MethylRAD)

  2019cites this paper
• Epha2 genotype influences ultraviolet radiation induced cataract in mice.

  2019cites this paper
• Analysis of digital gene expression profiling in the gonad of male silkworms (Bombyx mori) under fluoride stress.

  2018cites this paper
• Solar ultraviolet radiation cataract.

  2017cites this paper
• Regulatory effect of Bcl-2 in ultraviolet radiation-induced apoptosis of the mouse crystalline lens.

  2016cites this paper
• Exposure to subthreshold dose of UVR‐B induces apoptosis in the lens epithelial cells and does not in the lens cortical fibre cells

  2016influential citation
• Time evolution of active caspase‐3 labelling after in vivo exposure to UVR‐300 nm

  2014cites this paper
• Upregulation of GADD 45 a , TP 53 and CASP 3 mRNA Expression in the Rat Lens after In vivo Exposure to Subthreshold Dose of UVR B

  2014cites this paper
• Modelling the Time Evolution of Active Caspase-3 Protein in the Rat Lens after In Vivo Exposure to Ultraviolet Radiation-B

  2014cites this paper
• Evolution of TUNEL-labeling in the Rat Lens After In Vivo Exposure to Just Above Threshold Dose UVB

  2013cites this paper
• Ultraviolet Radiation Cataract

  2012cites this paper