Application of (1)h NMR spectroscopy-based metabolomics to sera of tuberculosis patients.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Proteome Research

• Publication date

  2013-10-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/pr4007359PMID 23980697PMCID PMC3838786
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genotype-Specific Abnormalities in Mitochondrial Function Associate with Distinct Profiles of Energy Metabolism and Catecholamine Content in Pheochromocytoma and Paraganglioma

  2013cited by this paper
• Urine Metabolomics Analysis for Biomarker Discovery and Detection of Jaundice Syndrome in Patients With Liver Disease*

  2012cited by this paper
• Metabolomic investigations of human infections.

  2012cited by this paper
• Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs.

  2012cited by this paper
• Correction: Biomarkers of Inflammation, Immunosuppression and Stress with Active Disease Are Revealed by Metabolomic Profiling of Tuberculosis Patients

  2012cited by this paper
• Biomarkers of Inflammation, Immunosuppression and Stress Are Revealed by Metabolomic Profiling of Tuberculosis Patients

  2012cited by this paper
• Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection

  2012cited by this paper
• 1 H-NMR-Based Metabolomics Study of Cerebral Infarction

  2011cited by this paper
• (1)H NMR-based metabolomic profiling in mice infected with Mycobacterium tuberculosis.

  2011cited by this paper
• Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.

  2011cited by this paper
• Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies.

  2011cited by this paper
• ^1H NMR-based Metabonomic Analysis of Metabolic Changes in Streptozotocin-induced Diabetic Rats

  2010cited by this paper
• MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data

  2010cited by this paper
• Quantitative Metabolomics by 1H-NMR and LC-MS/MS Confirms Altered Metabolic Pathways in Diabetes

  2010cited by this paper
• Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

  2010cited by this paper
• Use of Pharmaco‐Metabonomics for Early Prediction of Acetaminophen‐Induced Hepatotoxicity in Humans

  2010cited by this paper
• 1H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis

  2010cited by this paper
• Fast targeted multidimensional NMR metabolomics of colorectal cancer

  2009cited by this paper
• A metabonomic approach to early prognostic evaluation of experimental sepsis by 1H NMR and pattern recognition

  2009cited by this paper
• NMR‐based metabolomic analysis of cerebrospinal fluid and serum in neurological diseases – a diagnostic tool?

  2009cited by this paper
• Tuberculosis and host metabolism: ancient associations, fresh insights.

  2009cited by this paper
• Early stage diagnosis of oral cancer using 1H NMR-based metabolomics.

  2009cited by this paper
• Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

  2009cited by this paper
• Application of 1H NMR‐based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis

  2009cited by this paper
• Early Stage Diagnosis of Oral Cancer Using 1 H NMR – Based Metabolomics 1,2

  2009cited by this paper
• The Warburg Effect returns to the cancer stage.

  2009cited by this paper
• Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages

  2008cited by this paper
• Symbiotic gut microbes modulate human metabolic phenotypes

  2008cited by this paper
• Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

  2008cited by this paper
• Metabolic profiling reveals disorder of amino acid metabolism in four brain regions from a rat model of chronic unpredictable mild stress

  2008cited by this paper
• Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes.

  2008cited by this paper
• Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models.

  2008cited by this paper
• Chemometrics in metabonomics.

  2007cited by this paper
• Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

  2007cited by this paper
• OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification

  2006cited by this paper
• Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence

  2006cited by this paper
• From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

  2005cited by this paper
• Randomized controlled trial of nutritional supplementation in patients with newly diagnosed tuberculosis and wasting.

  2004cited by this paper
• Lactic acidosis

  2003cited by this paper
• Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

  2002cited by this paper
• 18-fluorodeoxyglucose positron emission tomographic imaging in the detection and monitoring of infection and inflammation.

  2002cited by this paper
• Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

  2000cited by this paper
• Tuberculosis, malnutrition and wasting.

  2000cited by this paper
• Malnutrition in tuberculosis.

  1999cited by this paper
• Whole body protein metabolism in human pulmonary tuberculosis and undernutrition: evidence for anabolic block in tuberculosis.

  1998cited by this paper
• Evaluating human breast ductal carcinomas with high-resolution magic-angle spinning proton magnetic resonance spectroscopy.

  1998cited by this paper
• 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma.

  1995cited by this paper
• Energy metabolism in trauma and sepsis: the role of fat.

  1983cited by this paper
• Lactic acidosis.

  1971cited by this paper

• NMR based human gut metabolomic profiling reveals altered metabolites associated with pulmonary and extra-pulmonary tuberculosis

  2025cites this paper
• Contemporary review on Metabolomic applications towards biomarker discovery and tuberculosis diagnosis

  2025cites this paper
• Plasma dynamic metabolomics during anti-tuberculosis treatment identifies an amino acid panel with diagnostic potential

  2025cites this paper
• Characterising the urinary acylcarnitine and amino acid profiles of HIV/TB co-infection, using LC–MS metabolomics

  2024cites this paper
• Biomarkers in diagnosing and therapeutic monitoring of tuberculosis: a review

  2024cites this paper
• Role of glutamine metabolism in tuberculosis pathogenesis: a mini review

  2024cites this paper
• Lung Mycobacterium tuberculosis infection perturbs metabolic pathways in non-pulmonary tissues

  2024cites this paper
• Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

  2024cites this paper
• Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis

  2024cites this paper
• Integrating untargeted and targeted LC-MS-based metabolomics to identify the serum metabolite biomarkers for tuberculosis.

  2024cites this paper
• Benchtop NMR-Based Metabolomics: First Steps for Biomedical Application

  2023cites this paper
• Clinical metabolomics by NMR revealed serum metabolic signatures for differentiating sarcoidosis from tuberculosis

  2023cites this paper
• The metabolic consequences of HIV/TB co-infection

  2023cites this paper
• Tuberculosis is associated with sputum metabolome variations, irrespective of patient sex or HIV status: an untargeted GCxGC-TOFMS study

  2023cites this paper
• Detection of mycobacterial pulmonary diseases via breath analysis in clinical practice

  2023cites this paper
• Evaluation of extraction methods for untargeted metabolomic studies for future applications in zebrafish larvae infection models

  2023cites this paper
• Small molecule bio‐signature in childhood intra‐thoracic tuberculosis identified by metabolomics

  2023cites this paper
• Probiotic Combination CBLEB Alleviates Streptococcus pneumoniae Infection Through Immune Regulation in Immunocompromised Rats

  2022cites this paper
• Therapeutic Potentials of Immunometabolomic Modulations Induced by Tuberculosis Vaccination

  2022cites this paper
• Mass Spectrometry-Based Proteomic and Metabolomic Profiling of Serum Samples for Discovery and Validation of Tuberculosis Diagnostic Biomarker Signature

  2022cites this paper
• Plasma metabolome of healthy and Rhodococcus equi-infected foals over time.

  2022cites this paper
• The Role of Amino Acids in Tuberculosis Infection: A Literature Review

  2022cites this paper
• Fumarate mitigates disruption induced by fenpropathrin in the silkworm Bombyx mori (Lepidoptera): A metabolomics study

  2022cites this paper
• Combining metabolome and clinical indicators with machine learning provides some promising diagnostic markers to precisely detect smear-positive/negative pulmonary tuberculosis

  2022cites this paper
• Tuberculous Granuloma: Emerging Insights From Proteomics and Metabolomics

  2022cites this paper
• Targeted metabolomics analysis of serum and Mycobacterium tuberculosis antigen-stimulated blood cultures of pediatric patients with active and latent tuberculosis

  2022cites this paper
• Unique Solvated Electron State and Its Remarkable Enhancement Effect on Internuclear J-Couplings in Fluorocarbon Cage Electron Clathrates

  2022cites this paper
• Using Omics to Study Leprosy, Tuberculosis, and Other Mycobacterial Diseases

  2022cites this paper
• Molecular perturbations in pulmonary tuberculosis patients identified by pathway-level analysis of plasma metabolic features

  2022cites this paper
• Urine metabolome of tuberculosis patients receiving intensive phase of treatment show diurnal variations.

  2021cites this paper
• Mass spectrometry-based identification of new serum biomarkers in patients with latent infection pulmonary tuberculosis

  2021cites this paper
• Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis

  2021cites this paper
• Benchtop nuclear magnetic resonance-based metabolomic approach for the diagnosis of bovine tuberculosis.

  2021cites this paper
• Differential Diagnosis of Latent Tuberculosis Infection and Active Tuberculosis: A Key to a Successful Tuberculosis Control Strategy

  2021cites this paper
• Metabolomics as a Tool to Investigate HIV/TB Co-Infection

  2021influential citation
• Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort

  2021cites this paper
• Use of Blood, Urine or Saliva-based Biomarkers in the Diagnosis of Active Pulmonary Tuberculosis-Sample Type Matters

  2021cites this paper
• Urine NMR-based TB metabolic fingerprinting for the diagnosis of TB in children

  2021cites this paper
• Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV

  2021cites this paper
• Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers discovery.

  2021cites this paper
• Active and prospective latent tuberculosis are associated with different metabolomic profiles: clinical potential for the identification of rapid and non-invasive biomarkers

  2020cites this paper
• Identification of serum biomarkers for active pulmonary tuberculosis using a targeted metabolomics approach

  2020cites this paper
• Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis

  2020cites this paper
• Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae

  2020cites this paper
• Pediatric Tuberculosis: The Impact of “Omics” on Diagnostics Development

  2020cites this paper
• Integrative Metabolomics to Identify Molecular Signatures of Responses to Vaccines and Infections

  2020cites this paper
• Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in children

  2020cites this paper
• Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker

  2020cites this paper
• Plasma metabolites Xanthine, 4-Pyridoxate, and d-glutamic acid as novel potential biomarkers for pulmonary tuberculosis.

  2019cites this paper
• 1H NMR-based metabolomic study of metabolic profiling for the urine of kidney stone patients

  2019cites this paper
• An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

  2019cites this paper
• High-resolution quantitative proteomics applied to the study of the specific protein signature in the sputum and saliva of active tuberculosis patients and their infected and uninfected contacts.

  2019cites this paper
• The application of metabolomics toward pulmonary tuberculosis research.

  2019cites this paper
• Tuberculosis: advances and challenges in development of new diagnostics and biomarkers.

  2018cites this paper
• Application of NMR metabolomics to search for human disease biomarkers in blood

  2018cites this paper
• Metabolomics applied to the discovery of tuberculosis and diabetes mellitus biomarkers.

  2018cites this paper
• Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection

  2017cites this paper
• Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells

  2017cites this paper
• Characterising tuberculosis and treatment failure thereof using metabolomics

  2017influential citation
• Metabolomics biomarkers for tuberculosis diagnostics: current status and future objectives.

  2017cites this paper
• High-throughput and computational approaches for diagnostic and prognostic host tuberculosis biomarkers.

  2017cites this paper
• Serum and Muscle Metabolomics for the Prediction of Ultimate pH, a Key Factor for Chicken-Meat Quality.

  2016cites this paper
• A putative urinary biosignature for diagnosis and follow-up of tuberculous meningitis in children: outcome of a metabolomics study disclosing host–pathogen responses

  2016cites this paper
• Diagnostic ‘omics’ for active tuberculosis

  2016cites this paper
• Adenylate kinase: a novel antigen for immunodiagnosis and subunit vaccine against tuberculosis

  2016cites this paper
• Lessons from black pepper: piperine and derivatives thereof

  2016cites this paper
• Tuberculous meningitis in infants and children : insights from nuclear magnetic resonance metabolomics

  2016cites this paper
• Identification of serum metabolic markers for diagnosis of women with dormant genital tuberculosis

  2016influential citation
• Systems Immunology: Approaches to Tuberculosis

  2016cites this paper
• Rapid Diagnosis of Tuberculosis from Analysis of Urine Volatile Organic Compounds.

  2016cites this paper
• Utility of Novel Plasma Metabolic Markers in the Diagnosis of Pediatric Tuberculosis: A Classification and Regression Tree Analysis Approach.

  2016cites this paper
• A metabolomics investigation of Tuberculous Meningitis in infants and children

  2016cites this paper
• NMR-based metabonomics for understanding the influence of dormant female genital tuberculosis on metabolism of the human endometrium.

  2016cites this paper
• Neglected diseases prioritized in Brazil under the perspective of metabolomics: A review

  2015cites this paper
• 1H NMR-Based Metabolic Profiling Reveals the Effects of Fluoxetine on Lipid and Amino Acid Metabolism in Astrocytes

  2015cites this paper
• Bioanalytical methods for metabolomic profiling: Detection of head and neck cancer, including oral cancer

  2015cites this paper
• Plasma metabonomic analysis reveals the effects of salvianic acid on alleviating acute alcoholic liver damage

  2015cites this paper
• DISCRIMINATION OF DENGUE DISEASE FROM HEALTHY BASED ON THE CHEMOMETRY OF 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

  2015cites this paper
• Metabolomics specificity of tuberculosis plasma revealed by (1)H NMR spectroscopy.

  2015cites this paper
• Laboratory diagnosis of melioidosis: Past, present and future

  2015cites this paper
• Metabolomic Profiling of Plasma from Patients with Tuberculosis by Use of Untargeted Mass Spectrometry Reveals Novel Biomarkers for Diagnosis

  2015cites this paper
• Deregulated tyrosine-phenylalanine metabolism in pulmonary tuberculosis patients.

  2015cites this paper
• Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway

  2015cites this paper
• Analysis of Serum Metabolic Profile by Ultra-performance Liquid Chromatography-mass Spectrometry for Biomarkers Discovery: Application in a Pilot Study to Discriminate Patients with Tuberculosis

  2015cites this paper
• Mycobacterium tuberculosis metabolism.

  2015influential citation
• Application of 1H NMR spectroscopy-based metabonomics to feces of cervical cancer patients with radiation-induced acute intestinal symptoms.

  2015cites this paper
• Identification of specific metabolites in culture supernatant of Mycobacterium tuberculosis using metabolomics: exploration of potential biomarkers

  2015cites this paper
• Can metabolomics improve tuberculosis diagnostics?

  2014cites this paper
• Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study

  2014cites this paper
• A hypothetical astrocyte–microglia lactate shuttle derived from a 1H NMR metabolomics analysis of cerebrospinal fluid from a cohort of South African children with tuberculous meningitis

  2014cites this paper