Synthetic, Switchable Enzymes

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Molecular Microbiology and Biotechnology

• Publication date

  2017-04-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1159/000464443PMID 28448969PMCID PMC5526678
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Flexibility, diversity, and cooperativity: pillars of enzyme catalysis.

  2011influential reference
• Computing with bacterial constituents, cells and populations: from bioputing to bactoputing

  2011cited by this paper
• Hidden alternate structures of proline isomerase essential for catalysis

  2010cited by this paper
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  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2009cited by this paper
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  2009cited by this paper
• Computational identification of slow conformational fluctuations in proteins.

  2009cited by this paper
• Microwave activation of enzymatic catalysis.

  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• Kinetic CE: Foundation for homogeneous kinetic affinity methods

  2007influential reference
• Dynamic personalities of proteins

  2007cited by this paper
• Enzymes: An integrated view of structure, dynamics and function

  2006cited by this paper
• The Dynamic Energy Landscape of Dihydrofolate Reductase Catalysis

  2006influential reference
• Relating protein motion to catalysis.

  2006cited by this paper
• Ion condensation and signal transduction.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
• Ribosome display: cell-free protein display technology.

  2002cited by this paper
• Communication between noncontacting macromolecules.

  2001cited by this paper
• Communication between noncontacting macromolecules

  2001cited by this paper
• Critical analysis of antibody catalysis.

  2000cited by this paper
• Immunological origins of binding and catalysis in a Diels-Alderase antibody.

  1998cited by this paper
• Solvation, Reorganization Energy, and Biological Catalysis*

  1998cited by this paper
• Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling.

  1997cited by this paper
• The Escherichia coli enzoskeleton

  1996cited by this paper
• Complexities of metabolic regulation.

  1994cited by this paper
• Dissection of an antibody-catalyzed reaction.

  1994cited by this paper
• Coupled oscillators and biological synchronization.

  1993cited by this paper
• Theory of low-frequency vibrations in DNA macromolecules.

  1991cited by this paper
• Bisubstrate Reaction Templates. Examination of the Consequences of Identical versus Different Binding Sites.

  1991influential reference
• Antibody catalysis of the Diels-Alder reaction

  1989cited by this paper
• Catalytic antibodies.

  1989cited by this paper
• Time-resolved photoacoustic calorimetry: probing the energetics and dynamics of fast chemical and biochemical reactions.

  1988cited by this paper
• Microwave Enhanced Diffusion in Polymeric Materials

  1988influential reference
• A Self‐Replicating Hexadeoxynucleotide

  1986cited by this paper
• Mechanism of the Diels-Alder reaction: reactions of butadiene with ethylene and cyanoethylenes.

  1986influential reference
• Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface.

  1985cited by this paper
• Template-directed synthesis on the pentanucleotide CpCpGpCpC.

  1984cited by this paper
• Studies on some interactions and reactions of oligonucleotides in aqueous solution.

  1966cited by this paper

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  2018cites this paper