Incidence of postoperative nausea and vomiting is not increased by combination of low concentration sevoflurane and propofol compared with propofol alone in patients undergoing laparoscopic gynecological surgery

BackgroundThe incidence of postoperative nausea and vomiting (PONV) is higher in patients receiving volatile anesthetics than those receiving total intravenous anesthesia (TIVA) with propofol. However, it is unclear whether its incidence is increased when a low concentration of sevoflurane is used in combination with propofol.MethodsThis prospective, randomized, controlled trial enrolled women undergoing laparoscopic gynecological surgery. Patients were randomly assigned to receive general anesthesia either with propofol alone (group P) or with 0.8% sevoflurane and propofol (group SP, n = 36, each group) for maintenance of anesthesia. The incidence of PONV and the number of patients who required antiemetics were compared.ResultsThere were no differences in the incidence of PONV and the number of patients who required antiemetics between the P and SP groups.ConclusionsA combination of 0.8% sevoflurane and propofol to maintain anesthesia does not increase the incidence of PONV compared with TIVA with propofol.Trial registrationUMIN-CTR UMIN000023647, registered 14 August 2016.

• Publication year

  2019

• Venue

  JA Clinical Reports

• Publication date

  2019-11-02

• Fields of study

  Medicine

• Identifiers
  DOI 10.1186/s40981-019-0292-4PMID 32026076PMCID 6966744
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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