Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Carcinogenesis

• Publication date

  2015-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/carcin/bgv138PMID 26424751PMCID PMC4635670
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.

  2015influential reference
• COSMIC: exploring the world's knowledge of somatic mutations in human cancer

  2014cited by this paper
• The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population.

  2014cited by this paper
• Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma.

  2014cited by this paper
• Identification of six new susceptibility loci for invasive epithelial ovarian cancer

  2014cited by this paper
• Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci

  2014cited by this paper
• Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

  2013cited by this paper
• Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  2013cited by this paper
• GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

  2013cited by this paper
• Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.

  2013cited by this paper
• Large-scale genotyping identifies 41 new loci associated with breast cancer risk

  2013cited by this paper
• Systematic identification of trans eQTLs as putative drivers of known disease associations

  2013cited by this paper
• Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

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• Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells

  2013cited by this paper
• Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium

  2012cited by this paper
• Large-scale association analysis identifies new risk loci for coronary artery disease

  2012cited by this paper
• Primary culture and immortalization of human fallopian tube secretory epithelial cells

  2012cited by this paper
• ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

  2012cited by this paper
• Cancer Facts & Figures 2012. American Cancer Society (ACS)

  2012cited by this paper
• HOCOMOCO: a comprehensive collection of human transcription factor binding sites models

  2012cited by this paper
• A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis.

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• Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study

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• Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

  2011cited by this paper
• Integrated Genomic Analyses of Ovarian Carcinoma

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• Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.

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  2010cited by this paper
• Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis.

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• A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

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• Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

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• Association between DNA Damage Response and Repair Genes and Risk of Invasive Serous Ovarian Cancer

  2010influential reference
• Common variants at 19p13 are associated with susceptibility to ovarian cancer

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• In vitro three‐dimensional modelling of human ovarian surface epithelial cells

  2009cited by this paper
• A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

  2009cited by this paper
• A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

  2009cited by this paper
• Functional Characterization of a Novel BRCA1-Null Ovarian Cancer Cell Line in Response to Ionizing Radiation

  2007cited by this paper
• The role of BRCA1 in transcriptional regulation and cell cycle control

  2006cited by this paper
• The many facets of the Wilms' tumour gene, WT1.

  2006cited by this paper
• Human DNA repair genes, 2005.

  2005cited by this paper
• A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro

  2004cited by this paper
• CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies.

  2004cited by this paper
• Ovulation-Induced DNA Damage in Ovarian Surface Epithelial Cells of Ewes: Prospective Regulatory Mechanisms of Repair/Survival and Apoptosis1

  2001cited by this paper
• Human DNA Repair Genes

  2001cited by this paper
• hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

  2000cited by this paper
• Brca1 controls homology-directed DNA repair.

  1999cited by this paper
• Relationship between lifetime ovulatory cycles and overexpression of mutant p53 in epithelial ovarian cancer.

  1997cited by this paper
• Identification of the breast cancer susceptibility gene BRCA2

  1995cited by this paper
• BRCA1 mutations in primary breast and ovarian carcinomas.

  1994cited by this paper
• A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

  1994cited by this paper
• Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

  year unknowncited by this paper
• Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

  year unknowncited by this paper

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• Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

  2024cites this paper
• High-Grade Serous Ovarian Cancer—A Risk Factor Puzzle and Screening Fugitive

  2024influential citation
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  2023cites this paper
• Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases

  2023cites this paper
• Genetic Predisposition to Breast and Ovarian Cancers: How Many and Which Genes to Test?

  2020cites this paper
• Application of magnetic nanoparticles in nucleic acid detection

  2020cites this paper
• BRIP1, RAD51C, and RAD51D mutations are associated with high susceptibility to ovarian cancer: mutation prevalence and precise risk estimates based on a pooled analysis of ~30,000 cases

  2020cites this paper
• DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

  2020cites this paper
• Invited Commentary Invited Commentary: Relationship Between Ovulation and Markers of Systemic Inflammation Versus Markers of Localized Inflammation

  2020cites this paper
• Epithelial ovarian cancer risk: A review of the current genetic landscape

  2019cites this paper
• Commentary: Estimated Lifetime Ovulatory Years and Its Determinants in Relation to Circulating Inflammatory Markers.

  2019cites this paper
• Detection of CHEK2 Ile157Thr mutation in cancer patients by using allele specific PCR

  2019cites this paper
• E2F2/5/8 Serve as Potential Prognostic Biomarkers and Targets for Human Ovarian Cancer

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2017cites this paper
• Inherited pancreatic cancer.

  2017cites this paper
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  2017influential citation
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• Exonuclease 1 and its versatile roles in DNA repair

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• Negative selection maintains transcription factor binding motifs in human cancer

  2015cites this paper