Neuroprotective potentials of candesartan, atorvastatin and their combination against stroke induced motor dysfunction

No abstract is available for this paper.

• Publication year

  2011

• Venue

  InflammoPharmacology

• Publication date

  2011-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s10787-010-0068-yPMID 21061073
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Methods of Enzymatic Analysis

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  2011cited by this paper
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  2010cited by this paper
• Nitric oxide mechanism in the protective effect of naringin against post-stroke depression (PSD) in mice.

  2010cited by this paper
• Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression.

  2010cited by this paper
• Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke.

  2010cited by this paper
• Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfusion injury and memory dysfunction

  2010cited by this paper
• Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.

  2010cited by this paper
• Protective effect of desipramine, venlafaxine and trazodone against experimental animal model of transient global ischemia: possible involvement of NO-cGMP pathway.

  2010cited by this paper
• Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability.

  2010cited by this paper
• Simvastatin and Atorvastatin Improve Neurological Outcome After Experimental Intracerebral Hemorrhage

  2009cited by this paper
• Analysis of SPARCL trial data for reduction of future stroke risk in older stroke patients with recent stroke or TIA.

  2009cited by this paper
• Statins: mechanisms of neuroprotection.

  2009cited by this paper
• Ischemia-Induced Mitochondrial Apoptosis is Significantly Attenuated by Ischemic Preconditioning

  2009cited by this paper
• The results support the use of atorvastatin in elderly patients with recent stroke or TIA.

  2009cited by this paper
• Effect of atorvastatin in elderly patients with a recent stroke or transient ischemic attack

  2009cited by this paper
• The usefulness of operant conditioning procedures to assess long-lasting deficits following transient focal ischemia in mice.

  2009cited by this paper
• EFFECT OF ATORVASTATIN IN ELDERLY PATIENTS WITH A RECENT STROKE OR TRANSIENT ISCHEMIC ATTACK

  2009cited by this paper
• Protective effect of naringin against ischemic reperfusion cerebral injury: possible neurobehavioral, biochemical and cellular alterations in rat brain.

  2009cited by this paper
• Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.

  2009cited by this paper
• Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.

  2008cited by this paper
• Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain.

  2008cited by this paper
• Atorvastatin attenuates mitochondrial toxin‐induced striatal degeneration, with decreasing iNOS/c‐Jun levels and activating ERK/Akt pathways

  2008cited by this paper
• Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat.

  2006cited by this paper
• AT1 Receptor Blockade Regulates the Local Angiotensin II System in Cerebral Microvessels From Spontaneously Hypertensive Rats

  2006cited by this paper
• Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke.

  2006cited by this paper
• Neuroprotective effect of Azadirachta indica on cerebral post-ischemic reperfusion and hypoperfusion in rats.

  2005cited by this paper
• Long-term protective effect of atorvastatin in permanent focal cerebral ischemia.

  2005influential reference
• Pleiotropic effects of statins.

  2005cited by this paper
• The Angiotensin II Type 1—Receptor Blocker Candesartan Increases Cerebral Blood Flow, Reduces Infarct Size, and Improves Neurologic Outcome after Transient Cerebral Ischemia in Rats

  2004cited by this paper
• The role of postischemic recirculation in the development of ischemic neuronal injury following complete cerebral ischemia

  2004cited by this paper
• The effects of monobromobimane on neuronal cell death in the hippocampus after transient global cerebral ischemia in rats.

  2004cited by this paper
• Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats

  2003influential reference
• Evaluation of Withania somnifera in a middle cerebral artery occlusion model of stroke in rats

  2003cited by this paper
• Treatment of acute ischemic stroke: recent progress.

  2002cited by this paper
• Mitochondrial DNA Damage and Dysfunction Associated With Oxidative Stress in Failing Hearts After Myocardial Infarction

  2001cited by this paper
• Chronic peripheral administration of the angiotensin II AT(1) receptor antagonist candesartan blocks brain AT(1) receptors.

  2000cited by this paper
• Molecular mechanisms of ischemic neuronal injury.

  2000cited by this paper
• Free Radical Pathways in CNS Injury

  2000cited by this paper
• Induced hypertension treatment to improve cerebral ischemic injury after transient forebrain ischemia.

  1999cited by this paper
• Blockade of central angiotensin AT(1) receptors improves neurological outcome and reduces expression of AP-1 transcription factors after focal brain ischemia in rats.

  1999cited by this paper
• Neuroprotective properties of statins in cerebral ischemia and stroke.

  1999cited by this paper
• Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria

  1999cited by this paper
• Changes in cerebral blood flow and blood brain barrier in the gerbil hippocampal CA1 region following repeated brief cerebral ischemia

  1999cited by this paper
• Effects of constraint-induced movement therapy on patients with chronic motor deficits after stroke: a replication.

  1999cited by this paper
• Role of mitochondria in oxidative stress and ageing.

  1998cited by this paper
• Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury.

  1998cited by this paper
• Mechanism of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction

  1997cited by this paper
• Reactive Oxygen Species and the Central Nervous System

  1992cited by this paper
• Brain and pituitary angiotensin.

  1992cited by this paper
• The rehabilitation of elderly stroke patients.

  1991cited by this paper
• Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion.

  1990cited by this paper
• Effect of angiotensin II and peptide YY on cerebral and circumventricular blood flow.

  1988cited by this paper
• Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids.

  1982influential reference
• Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase.

  1978cited by this paper
• Diencephalic and hippocampal mechanisms of motor activity in the rat: effects of posterior hypothalamic stimulation on behavior and hippocampal slow wave activity.

  1972cited by this paper
• AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA

  1967cited by this paper
• [58] Preparation of succinate dehydrogenase and reconstitution of succinate oxidase

  1967cited by this paper
• [52] Preparations and properties of soluble NADH dehydrogenases from cardiac muscle

  1967cited by this paper
• Mechanisms of lipid peroxide formation in animal tissues.

  1966cited by this paper
• Determination of serum proteins by means of the biuret reaction.

  1949cited by this paper

• Neuroprotective effects of candesartan in 3-nitropropionic acid-induced Huntington’s disease: modulation of angiotensin and CREB/BDNF/PGC1-α signaling

  2025cites this paper
• Mitochondrial Effects of Common Cardiovascular Medications: The Good, the Bad and the Mixed

  2022cites this paper
• Simvastatin Improves Microcirculatory Function in Nonalcoholic Fatty Liver Disease and Downregulates Oxidative and ALE-RAGE Stress

  2022cites this paper
• A prognostic study on the effect of post-traumatic stress disorder on cerebral ischaemia reperfusion-induced stroke

  2021cites this paper
• The Role of Sartans in the Treatment of Stroke and Subarachnoid Hemorrhage: A Narrative Review of Preclinical and Clinical Studies

  2020cites this paper
• Inhibition of Methamphetamine Self-Administration and Reinstatement by Central Blockade of Angiotensin II Receptor in Rats

  2019cites this paper
• Improved Histoarchitectural Changes with Angiotensin Receptor Blockers in Early Testicular and Cauda Toxicity in Rats

  2019cites this paper
• Effect of atorvastatin on behavioral alterations and neuroinflammation during epileptogenesis.

  2018cites this paper
• Transient global cerebral ischemia differentially affects cortex, striatum and hippocampus in Bilateral Common Carotid Arterial occlusion (BCCAo) mouse model.

  2018cites this paper
• Angiotensin II-mediated suppression of synaptic proteins in mouse hippocampal neuronal HT22 cell was inhibited by propofol: role of calcium signaling pathway

  2018cites this paper
• Candesartan and epigallocatechin‐3‐gallate ameliorate gentamicin‐induced renal damage in rats through p38‐MAPK and NF‐κB pathways

  2018cites this paper
• Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats

  2017cites this paper
• Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity

  2016cites this paper
• Journal of Pharmaceutical and Biological Sciences

  2015cites this paper
• Statins enhance cognitive performance in object location test in albino Swiss mice: involvement of beta-adrenoceptors.

  2015cites this paper
• Pathophysiology and Treatments of Oxidative Injury in Ischemic Stroke: Focus on the Phagocytic NADPH Oxidase 2

  2015cites this paper
• Angiotensin II-induced mouse hippocampal neuronal HT22 cell apoptosis was inhibited by propofol: Role of neuronal nitric oxide synthase and metallothinonein-3.

  2015cites this paper
• HIGH-FAT DIET-INDUCED OBESITY IS ATTENUATED BY DATE SEED EXTRACT IN RAT MODEL

  2014cites this paper
• Candesartan and glycyrrhizin ameliorate ischemic brain damage through downregulation of the TLR signaling cascade.

  2014cites this paper
• Rosiglitazone Synergizes the Neuroprotective Effects of Valproic Acid Against Quinolinic Acid-Induced Neurotoxicity in Rats: Targeting PPARγ and HDAC Pathways

  2014cites this paper
• Amelioration of Stroke-Induced Neurological Deficiency by Lyophilized Powder of Catapol and Puerarin

  2014cites this paper
• Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats.

  2013cites this paper
• Effect of atorvastatin on phenytoin-induced osteoporosis in adult albino rats: a pharmacological and light and electron microscopic study

  2013cites this paper
• Cerebroprotective Effect of Date Seed Extract (Phoenix dactylifera) on Focal Cerebral Ischemia in Male Rats

  2012cites this paper
• Effects of progesterone on brain infarct size and locomotor activity in transient focal cerebral ischemic male rats

  2012cites this paper
• Coffee Component 3-Caffeoylquinic Acid Increases Antioxidant Capacity but not Polyphenol Content in Experimental Cerebral Infarction

  2012cites this paper
• Reperfusion brain injury

  2012cites this paper
• Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury

  2012influential citation
• The Protective Effect of Ethanolic Extract of Sida Tiagii Bhandari Seeds Against Complete Freund's Adjuvant Induced Experimental Animal Model of Rheumatoid Arthritis

  2011cites this paper
• Possible nitric oxide mechanism in the protective effect of hesperidin against ischemic reperfusion cerebral injury in rats.

  2011cites this paper
• Protective effect of Etoricoxib against middle cerebral artery occlusion induced transient focal cerebral ischemia in rats.

  2011cites this paper