A Novel Colonic Repressor Element Regulates Intestinal Gene Expression by Interacting with Cux/CDP

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular and Cellular Biology

• Publication date

  2002-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.22.15.5467-5478.2002PMID 12101240PMCID PMC133930
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sucrase-isomaltase Gene Transcription Requires the Hepatocyte Nuclear Factor-1 (HNF-1) Regulatory Element and Is Regulated by the Ratio of HNF-1α to HNF-1β*

  2001cited by this paper
• Identification of CCAAT Displacement Protein (CDP/cut) as a Locus-specific Repressor of Major Histocompatibility Complex Gene Expression in Human Tumor Cells*

  2001cited by this paper
• Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice.

  2001influential reference
• Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity.

  2001influential reference
• Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta.

  2001influential reference
• S Phase-Specific Proteolytic Cleavage Is Required To Activate Stable DNA Binding by the CDP/Cut Homeodomain Protein

  2001cited by this paper
• The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.

  2001cited by this paper
• Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development.

  2001cited by this paper
• The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6

  2000cited by this paper
• TRANSFAC: an integrated system for gene expression regulation

  2000cited by this paper
• CCAAT Displacement Activity Involves CUT Repeats 1 and 2, Not the CUT Homeodomain*

  2000cited by this paper
• The Nuclear Matrix Protein CDP Represses Hepatic Transcription of the Human Cholesterol-7α Hydroxylase Gene*

  2000cited by this paper
• Cdx1 and cdx2 expression during intestinal development.

  2000cited by this paper
• The CCAAT displacement protein/cut homeodomain protein represses osteocalcin gene transcription and forms complexes with the retinoblastoma protein-related protein p107 and cyclin A.

  1999cited by this paper
• Transcriptional Repression of the Cystic Fibrosis Transmembrane Conductance Regulator Gene, Mediated by CCAAT Displacement Protein/cut Homolog, Is Associated with Histone Deacetylation*

  1999cited by this paper
• The mammalian Cut homeodomain protein functions as a cell‐cycle‐dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase

  1998cited by this paper
• Primary cultures of fully differentiated and pure human intestinal epithelial cells.

  1998cited by this paper
• Identification of c-MYC as a target of the APC pathway.

  1998cited by this paper
• Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific.

  1997cited by this paper
• Positive and negative regulation of the human thymidine kinase promoter mediated by CCAAT binding transcription factors NF-Y/CBF, dbpA, and CDP/cut.

  1997cited by this paper
• Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter.

  1997influential reference
• Primary Structure, Neural-specific Expression, and Chromosomal Localization of Cux-2, a Second Murine Homeobox Gene Related to Drosophila cut*

  1996cited by this paper
• An intestine-specific homeobox gene regulates proliferation and differentiation

  1996influential reference
• The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy

  1996influential reference
• Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines.

  1995cited by this paper
• DNA-binding specificity of the cut repeats from the human cut-like protein

  1995cited by this paper
• Gastrointestinal cancers : biology, diagnosis, and therapy

  1995cited by this paper
• Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes

  1995cited by this paper
• Human Intestinal Brush Border Membrane Hydrolases

  1994cited by this paper
• The human cut homeodomain protein represses transcription from the c-myc promoter

  1994cited by this paper
• A homeodomain protein related to caudal regulates intestine-specific gene transcription

  1994cited by this paper
• Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.

  1994cited by this paper
• Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter.

  1994cited by this paper
• The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice.

  1993cited by this paper
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  1993cited by this paper
• HNF-1 alpha and HNF-1 beta expression in mouse intestinal crypts.

  1993influential reference
• Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila.

  1993cited by this paper
• Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

  1992influential reference
• Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene

  1992cited by this paper
• Oncogene-mediated transformation of fetal rat colon in vitro.

  1992cited by this paper
• Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer.

  1991cited by this paper
• Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells.

  1991cited by this paper
• Expression of enzymatically active sucrase-isomaltase is a ubiquitous property of colon adenocarcinomas.

  1991cited by this paper
• Detection and characterization of sucrase-isomaltase in adult human colon and in colonic polyps.

  1990cited by this paper
• Sucrase‐isomaltase expression and enterocytic ultrastructure of human colorectal tumors

  1989cited by this paper
• Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila

  1988cited by this paper
• Development of the gastrointestinal tract

  1986cited by this paper
• Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

  1983cited by this paper
• Sucrase‐isomaltase: A marker of foetal and malignant epithelial cells of the human colon

  1983cited by this paper

• Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity

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  2017cites this paper
• Identification of GATA-4 as a novel transcriptional regulatory component of regenerating islet-derived family members.

  2015cites this paper
• Polycomb repressive complex 2 impedes intestinal cell terminal differentiation

  2012influential citation
• Cux1 transcription factor is induced in inflammatory bowel disease and protects against experimental colitis†

  2010cites this paper
• The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT‐Displacement‐Protein (CUX1) repressor

  2010cites this paper
• CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.

  2010cites this paper
• Regulation of cell proliferation and differentiation in the kidney.

  2009cites this paper
• Hepatocyte nuclear factor 4 contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation

  2009cites this paper
• Nuclear Receptor Co-repressor Is Required to Maintain Proliferation of Normal Intestinal Epithelial Cells in Culture and Down-modulates the Expression of Pigment Epithelium-derived Factor*

  2009cites this paper
• The multiple roles of CUX1: insights from mouse models and cell-based assays.

  2008cites this paper
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  2007cites this paper
• CDX2 : un facteur à multiples facettes pour les cellules épithéliales du tube digestif

  2007cites this paper
• [CDX2: a transcription factor with multiple tasks for epithelial cells of the digestive tract].

  2007cites this paper
• Intestinal Specific Gene Regulation by Transcription Factors Gata4 and Hnfla in Vivo

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• Functional Characterization of the CCL25 Promoter in Small Intestinal Epithelial Cells Suggests a Regulatory Role for Caudal-Related Homeobox (Cdx) Transcription Factors1

  2006cites this paper
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  2006cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004influential citation
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  2002cites this paper