Mis‐sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal

No abstract is available for this paper.

• Publication year

  1997

• Venue

  International Journal of Cancer

• Publication date

  1997-03-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/(SICI)1097-0215(19970304)70:5<561::AID-IJC12>3.0.CO;2-GPMID 9052756
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Organ distribution of experimental metastases of a human colorectal carcinoma injected in nude mice

  2005cited by this paper
• Differential Metabolic Effects of Adenovirus-mediated Glucokinase and Hexokinase I Overexpression in Rat Primary Hepatocytes*

  1996cited by this paper
• Re-expression of the Mannose 6-Phosphate Receptors in Receptor-deficient Fibroblasts

  1996cited by this paper
• Cathepsin D and breast cancer.

  1996cited by this paper
• Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors.

  1995cited by this paper
• Physiological functions of endosomal proteolysis.

  1995cited by this paper
• Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.

  1995cited by this paper
• Altered intracellular processing and enhanced secretion of procathepsin D in a highly deviated rat hepatoma

  1995cited by this paper
• Mitogenic function of human procathepsin D: the role of the propeptide.

  1994cited by this paper
• Specific mannose-6-phosphate receptor-independent sorting of pro-cathepsin D in breast cancer cells.

  1994cited by this paper
• Cathepsin D in the malignant progression of neoplastic diseases (review).

  1992cited by this paper
• Theearly andlate processing of lysosomal enzymes: Proteolysis and compartmentation

  1992cited by this paper
• Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells.

  1991cited by this paper
• Determination of the Phosphorylation, Uncovering of Mannose 6-Phosphate Groups and Targeting of Lysosomal Enzymes

  1991cited by this paper
• Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

  1990cited by this paper
• Cathepsin D in breast cancer cells can digest extracellular matrix in large acidic vesicles.

  1990cited by this paper
• Suppression of the 'uncovering' of mannose-6-phosphate residues in lysosomal enzymes in the presence of NH4Cl.

  1990cited by this paper
• On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.

  1987cited by this paper
• Effects of differentiation-inducing agents on synthesis, maturation and secretion of cathepsin D in U937 and HL-60 cells.

  1987cited by this paper
• Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells

  1987cited by this paper
• Lysosomal enzymes and their receptors.

  1986cited by this paper
• Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52 K protein.

  1986cited by this paper
• Possible pathways for lysosomal enzyme delivery

  1985cited by this paper
• Tumorigenicity and transcriptional modulation of c-myc and N-ras oncogenes in a human hepatoma cell line.

  1985cited by this paper
• Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts

  1982cited by this paper
• Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2.

  1982cited by this paper
• Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

  1980cited by this paper
• Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen.

  1980cited by this paper
• In vitro cultivation of human tumor tissues. II. Morphological and virological characterization of three cell lines.

  1978cited by this paper
• Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

  1976cited by this paper
• New Human Tumor Cell Lines

  1975cited by this paper
• A human cell line from a pleural effusion derived from a breast carcinoma.

  1973cited by this paper

• Prostate cell lines as models for biomarker discovery: Performance of current markers and the search for new biomarkers

  2014cites this paper
• Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice

  2014cites this paper
• The dilemma: Does tissue expression of cathepsin D reflect tumor malignancy? The question: Does the assay truly mirror cathepsin D mis-function in the tumor?

  2010cites this paper
• Proteinases and their inhibitors in liver cancer.

  2009cites this paper
• Role of altered pH homeostasis and hypoxia in the phenotypic changes of cancer cells

  2009cites this paper
• Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini.

  2008cites this paper
• Cathepsin D: a cellular roadmap.

  2008cites this paper
• Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells

  2005cites this paper
• Increased cathepsin D release by Hyp mouse osteoblast cells.

  2005cites this paper
• Defective Acidification of Intracellular Organelles Results in Aberrant Secretion of Cathepsin D in Cancer Cells*

  2004cites this paper
• Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions

  2004cites this paper
• Biosynthesis and alternate targeting of the lysosomal cysteine protease cathepsin L.

  2004cites this paper
• Etude du rôle des lysosomes et du cholestérol au cours de la différenciation des kératinocytes épidermiques

  2004influential citation
• Verapamil regulates activity and mRNA-expression of human β-glucuronidase in HepG2 cells

  2003cites this paper
• Destination ‘Lysosome’: a target organelle for tumour cell killing?

  2003influential citation
• Procathepsin D interacts with prosaposin in cancer cells but its internalization is not mediated by LDL receptor-related protein.

  2002cites this paper
• Glucose regulates protein catabolism in ras-transformed fibroblasts through a lysosomal-dependent proteolytic pathway.

  2001cites this paper
• Regulation of Human β-Glucuronidase by A23187 and Thapsigargin in the Hepatoma Cell Line HepG2

  2001cites this paper
• Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2.

  2001cites this paper
• Regulation of Human b-Glucuronidase by A 23187 and Thapsigargin in the Hepatoma Cell Line HepG 2

  2001cites this paper
• Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview.

  2000cites this paper
• Transformation by oncogenic ras‐p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D

  1999cites this paper
• The half-life of human procathepsin S.

  1999cites this paper
• Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells.

  1998cites this paper
• Endocytosis of pro-cathepsin D into breast cancer cells is mostly independent of mannose-6-phosphate receptors.

  1998cites this paper
• Abnormal lysosomal sorting with an enhanced secretion of cathepsin D precursor molecules bearing monoester phosphate groups.

  1998cites this paper
• Expression and posttranslational fate of cathepsin D in HT-29 tumor cells depend on their enterocytic differentiation state.

  1997cites this paper
• Differentiation-induced changes in the content, secretion, and subcellular distribution of lysosomal cathepsins in the human colon cancer HT-29 cell line

  1997cites this paper