Anti-apoptotic BCL-2 family proteins confer resistance to calicheamicin-based antibody-drug conjugate therapy of acute leukemia

C. Godwin,Olivia M. Bates,S. Jean,G. S. Laszlo,Eliotte E. Garling,Mary E. Beddoe,M. Cardone,R. Walter

Published 2020 in Leukemia and Lymphoma

ABSTRACT

Over 26,000 people will face a new diagnosis of acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) in 2020 in the U.S. alone, and only a minority will be long-term survivors [1]. Am...

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