Gene regulation in cancer gene therapy strategies.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Current Medicinal Chemistry

• Publication date

  2003-09-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2174/0929867033456837PMID 12871091
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Use of the human MDR1 promoter for heat‐inducible expression of therapeutic genes

  2002cited by this paper
• Adenovirus-mediated transfer of inducible caspases: a novel "death switch" gene therapeutic approach to prostate cancer.

  2001cited by this paper
• Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters

  2001cited by this paper
• Regulated Gene Expression in Glioma Cells: A Comparison of Three Inducible Systems

  2001cited by this paper
• Increasing specificity of anti-tumor therapy: cytotoxic protein delivery by non-pathogenic clostridia under regulation of radio-induced promoters.

  2001cited by this paper
• Heat-inducible TNF-α gene therapy combined with hyperthermia using magnetic nanoparticles as a novel tumor-targeted therapy

  2001cited by this paper
• Regulating genes with electromagnetic response elements

  2001cited by this paper
• Replicating adenoviral vector–mediated transfer of a heat-inducible double suicide gene for gene therapy

  2001cited by this paper
• Radio-responsive recA promoter significantly increases TNFα production in recombinant clostridia after 2 Gy irradiation

  2001cited by this paper
• A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease.

  2001cited by this paper
• mdr1 promoter-driven tumor necrosis factor-α expression for a chemotherapy-controllable combined in vivo gene therapy and chemotherapy of tumors

  2000cited by this paper
• Development of synthetic promoters for radiation-mediated gene therapy

  2000cited by this paper
• Targeting and eradicating cancer cells by a prostate-specific vector carrying the diphtheria toxin A gene

  2000cited by this paper
• Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy

  2000cited by this paper
• Regulatable systems: applications in gene therapy and replicating viruses.

  2000cited by this paper
• Eradication of Breast Cancer Xenografts by Hyperthermic Suicide Gene Therapy under the Control of the Heat Shock Protein Promoter

  2000cited by this paper
• A radiation-controlled molecular switch for use in gene therapy of cancer

  2000cited by this paper
• Adenoviral vector which delivers FasL–GFP fusion protein regulated by the tet-inducible expression system

  2000cited by this paper
• Modification of vascular tone using iNOS under the control of a radiation-inducible promoter

  2000cited by this paper
• Cancer gene therapy by thyroid hormone-mediated expression of toxin genes.

  2000cited by this paper
• Advances in plasmid gene delivery and expression in skeletal muscle.

  2000cited by this paper
• Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum.

  2000cited by this paper
• Control of parvovirus DNA replication by a tetracycline-regulated repressor

  1999cited by this paper
• Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer.

  1999cited by this paper
• Suppression of gene expression by tethering KRAB domain to promoter of ER target genes.

  1999cited by this paper
• Adenovirus-mediated regulable target gene expression in vivo.

  1999cited by this paper
• Long-term regulated expression of growth hormone in mice after intramuscular gene transfer.

  1999cited by this paper
• Regression of Hepatocellular Carcinoma in Vitro and in Vivo by Radiosensitizing Suicide Gene Therapy under the Inducible and Spatial Control of Radiation

  1999cited by this paper
• In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system

  1999cited by this paper
• Tet B or not tet B: advances in tetracycline-inducible gene expression.

  1999cited by this paper
• Controlling gene expression in living cells through small molecule-RNA interactions.

  1998cited by this paper
• Microwave applications in clinical medicine

  1998cited by this paper
• Gene-directed enzyme prodrug therapy.

  1998cited by this paper
• Invited. On the feasibility of MRI‐guided focused ultrasound for local induction of gene expression

  1998cited by this paper
• Transgene Expression in Malignant Glioma Using a Replication-Defective Adenoviral Vector Containing the Egr-1 Promoter: Activation by Ionizing Radiation or Uptake of Radioactive Iododeoxyuridine

  1998cited by this paper
• Inducible gene expression in mammalian cells and transgenic mice.

  1997cited by this paper
• Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts

  1997cited by this paper
• Controlling mammalian gene expression with small molecules.

  1997cited by this paper
• Induction of the Suicide HSV–TK Gene by Activation of the Egr-1 Promoter with Radioisotopes

  1997cited by this paper
• A humanized system for pharmacologic control of gene expression

  1996cited by this paper
• Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

  1996cited by this paper
• Transcriptional activation by tetracyclines in mammalian cells.

  1995cited by this paper
• Activation of the Radiosensitive EGR-1 Promoter Induces Expression of the Herpes Simplex Virus Thymidine Kinase Gene and Sensitivity of Human Glioma Cells to Ganciclovir

  1995cited by this paper
• Spatial and temporal control of gene therapy using ionizing radiation

  1995cited by this paper
• Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements.

  1994cited by this paper
• The induction of gene expression in mammalian cells by radiation.

  1993cited by this paper
• Heat‐shock responsive elements in the induction of the multidrug resistance gene (MDR1)

  1992cited by this paper
• Retroviral-mediated transfer and amplification of a functional human factor VIII gene.

  1990cited by this paper
• Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA.

  1990cited by this paper
• An auto-inducible vector conferring high glucocorticoid inducibility upon stable transformant cells.

  1989cited by this paper

• Suicide Gene Therapy

  2003cites this paper