Hypoxia downregulates Ku70/80 expression in cervical carcinoma tumors.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Radiotherapy and Oncology

• Publication date

  2008-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.radonc.2008.07.018PMID 18706726
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007influential reference
• Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy

  2006cited by this paper
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  2006cited by this paper
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  2006influential reference
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  2005influential reference
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  2005cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
• Oxygenation predicts radiation response and survival in patients with cervix cancer.

  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
• DNA repair in eukaryotes.

  1996cited by this paper
• Cervix uteri.

  1960cited by this paper

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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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  2011influential citation
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper