Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis?

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Annals of Neurology

• Publication date

  2017-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ana.24944PMID 28470695
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RNA Regulation of Lipotoxicity and Metabolic Stress

  2016cited by this paper
• Oligodendrogliopathy in Multiple Sclerosis: Low Glycolytic Metabolic Rate Promotes Oligodendrocyte Survival

  2016influential reference
• Phosphorylated heat shock protein 27 promotes lipid clearance in hepatic cells through interacting with STAT3 and activating autophagy.

  2016cited by this paper
• Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

  2016cited by this paper
• Dynamics of the association of heat shock protein HSPA6 (Hsp70B’) and HSPA1A (Hsp70–1) with stress-sensitive cytoplasmic and nuclear structures in differentiated human neuronal cells

  2016cited by this paper
• Cause and prevention of demyelination in a model multiple sclerosis lesion

  2016cited by this paper
• Potential role for snoRNAs in PKR activation during metabolic stress

  2015cited by this paper
• Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) Is Dynamically Regulated by NADPH Oxidase*

  2015cited by this paper
• CNS myelin sheath is stochastically built by homotypic fusion of myelin membranes within the bounds of an oligodendrocyte process.

  2015cited by this paper
• Activation of necroptosis in multiple sclerosis.

  2015influential reference
• The emerging landscape of small nucleolar RNAs in cell biology

  2015influential reference
• Characterization of glucose‐related metabolic pathways in differentiated rat oligodendrocyte lineage cells

  2015influential reference
• Aerobic glycolysis in the primate brain: reconsidering the implications for growth and maintenance

  2014cited by this paper
• Dynamics of oligodendrocyte generation and myelination in the human brain.

  2014cited by this paper
• Spare mitochondrial respiratory capacity permits human adipocytes to maintain ATP homeostasis under hypoglycemic conditions

  2014cited by this paper
• Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue.

  2014cited by this paper
• Activation of Autophagy by Rapamycin Does Not Protect Oligodendrocytes Against Protein Aggregate Formation and Cell Death Induced by Proteasomal Inhibition

  2014cited by this paper
• Analysis and interpretation of microplate-based oxygen consumption and pH data.

  2014cited by this paper
• The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF‐1 signaling in rat and human oligodendrocyte progenitors

  2014cited by this paper
• Neurological deficits caused by tissue hypoxia in neuroinflammatory disease

  2013cited by this paper
• Oligodendrocyte Plasticity with an Intact Cell Body In Vitro

  2013cited by this paper
• Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis.

  2013influential reference
• Oligodendrocytes and the early multiple sclerosis lesion

  2012cited by this paper
• Oligodendrocyte Precursor Cell Transplantation into Organotypic Cerebellar Shiverer Slices: A Model to Study Myelination and Myelin Maintenance

  2012cited by this paper
• Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress.

  2011cited by this paper
• REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

  2011influential reference
• Response of Human Oligodendrocyte Progenitors to Growth Factors and Axon Signals

  2010cited by this paper
• Oligodendrocyte degeneration and recovery after focal cerebral ischemia.

  2010cited by this paper
• GAGE: generally applicable gene set enrichment for pathway analysis

  2009cited by this paper
• Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

  2008cited by this paper
• p38 mitogen‐activated protein kinase is required for central nervous system myelination

  2007cited by this paper
• Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

  2006cited by this paper
• Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation

  2005cited by this paper
• The efficiency and plasticity of mitochondrial energy transduction.

  2005cited by this paper
• The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage

  2005cited by this paper
• Distinctive properties of human adult brain-derived myelin progenitor cells.

  2004cited by this paper
• Evidence for pathogenic heterogeneity in multiple sclerosis

  2004cited by this paper
• Bioconductor: open software development for computational biology and bioinformatics

  2004cited by this paper
• Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication

  2003influential reference
• Hypoxia-like tissue injury as a component of multiple sclerosis lesions

  2002cited by this paper
• Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

  1997cited by this paper
• Oxidative damage to proteins and lipids of CNS myelin produced by in vitro generated reactive oxygen species

  1995cited by this paper
• Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury

  1995influential reference
• Ultrastructure of multiple sclerosis.

  1994cited by this paper
• Multiple sclerosis: immune system molecule expression in the central nervous system.

  1994cited by this paper
• Patterns of oligodendroglia pathology in multiple sclerosis.

  1994cited by this paper
• Phosphorylation and disruption of intermediate filament proteins in oligodendrocyte precursor cultures treated with calyculin A

  1993cited by this paper
• Oligodendrocyte injury is an early event in lesions of multiple sclerosis.

  1993cited by this paper
• Virus-induced alterations in homeostasis: alteration in differentiated functions of infected cells in vivo.

  1982cited by this paper
• Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system.

  1981cited by this paper
• Evidence for a “dying‐back” gliopathy in demyelinating disease

  1981cited by this paper
• Immunocytochemical observations on the distribution of myelin‐associated glycoprotein and myelin basic protein in multiple sclerosis lesions

  1980cited by this paper
• Monoclonal antibody to a plasma membrane antigen of neurons.

  1979cited by this paper

• Dying oligodendrocytes persist without mitochondria

  2026cites this paper
• Energy for myelination: Implications for metabolic disturbances in multiple sclerosis pathology.

  2025cites this paper
• Neuroimmune interactions: How past lessons can inform the present and future of MS care

  2025influential citation
• Cellular Senescence in Glial Cells: Implications for Multiple Sclerosis

  2025cites this paper
• Regulation of stress granule formation in human oligodendrocytes

  2024cites this paper
• Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells

  2024cites this paper
• Should We Consider Neurodegeneration by Itself or in a Triangulation with Neuroinflammation and Demyelination? The Example of Multiple Sclerosis and Beyond

  2024cites this paper
• Age-dependent effects of metformin on human oligodendrocyte lineage cell ensheathment capacity

  2024cites this paper
• Seeking neuroprotection in multiple sclerosis: an ongoing challenge

  2023cites this paper
• Activated leukocyte cell adhesion molecule on human oligodendrocytes mediates CD4 T cell adhesion.

  2023cites this paper
• Mechanisms of metabolic stress induced cell death of human oligodendrocytes: relevance for progressive multiple sclerosis

  2023cites this paper
• Oligodendrocyte progenitor cell recruitment and remyelination in multiple sclerosis: the more, the merrier?

  2022cites this paper
• Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes

  2022influential citation
• Journal Pre-proofs A comparative assessment of myelin-sensitive measures in multiple sclerosis patients and healthy subjects

  2022cites this paper
• MicroRNA-210 regulates the metabolic and inflammatory status of primary human astrocytes

  2022cites this paper
• Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis.

  2022cites this paper
• A comparative assessment of myelin-sensitive measures in multiple sclerosis patients and healthy subjects

  2022cites this paper
• Chronic oligodendrocyte injury in central nervous system pathologies

  2022cites this paper
• Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation

  2021cites this paper
• Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways

  2021cites this paper
• Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging

  2021cites this paper
• Oligodendroglial Energy Metabolism and (re)Myelination

  2021cites this paper
• Developmental trajectory of oligodendrocyte progenitor cells in the human brain revealed by single cell RNA sequencing

  2020cites this paper
• In vivo spatiotemporal patterns of oligodendrocyte and myelin damage at the neural electrode interface.

  2020cites this paper
• Oligodendrocyte progenitors as environmental biosensors.

  2020cites this paper
• Effects of Biotin on survival, ensheathment, and ATP production by oligodendrocyte lineage cells in vitro

  2020cites this paper
• RNA-binding protein altered expression and mislocalization in MS

  2020cites this paper
• Novel Molecular Leads for the Prevention of Damage and the Promotion of Repair in Neuroimmunological Disease

  2019cites this paper
• RNA-binding protein altered expression and mislocalization in multiple sclerosis

  2019cites this paper
• The Role of Vesicle Trafficking and Release in Oligodendrocyte Biology

  2019cites this paper
• Species differences in immune‐mediated CNS tissue injury and repair: A (neuro)inflammatory topic

  2019cites this paper
• Myelin in the Central Nervous System: Structure, Function, and Pathology.

  2019cites this paper
• Demyelination with preferential MAG loss: A complex message from MS paraffin blocks.

  2018cites this paper
• Oligodendrocyte generation dynamics in multiple sclerosis

  2018cites this paper
• The adult oligodendrocyte can participate in remyelination

  2018cites this paper
• Multiple sclerosis pathogenesis: missing pieces of an old puzzle

  2018cites this paper
• Distinct age and differentiation-state dependent metabolic profiles of oligodendrocytes under optimal and stress conditions

  2017cites this paper