Periodontal disease might be a risk factor for graft versus host disease. A systematic review.

PURPOSE The aim of this systematic review was to determine a potential association between periodontal disease and graft versus host disease (GVHD). DESIGN PubMed, Scopus and Web of Science databases were searched to identify all relevant articles. The eligibility criteria were prospective, retrospective, cross-sectional, cohort, case-control studies and interventional studies that assessed periodontal parameters in GVHD adults' patients. RESULTS Seven studies, published between 2000 and 2018, were eligible. The aggravation of periodontal tissues is due to inadequate oral hygiene, dental plaque, decays, gum recession, retained roots, tooth loss, periodontally infected teeth. Several studies have indicated that periodontitis treatment performed before transplantation showed the reduction of gingival inflammation and maintenance of periodontal health. CONCLUSIONS Periodontitis might be a risk factor for GVHD. However, due to the limited number of studies included in the review and their heterogeneity, more data are needed to sustain the correlation between periodontitis and GVHD.

• Publication year

  2020

• Venue

  Critical reviews in oncology/hematology

• Publication date

  2020-01-23

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.critrevonc.2020.102878PMID 32000068
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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