The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Oncogene

• Publication date

  1999-04-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1202584PMID 10327051
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

  1998cited by this paper
• p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells.

  1998cited by this paper
• Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.

  1998cited by this paper
• Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors.

  1997cited by this paper
• Binding and modulation of p53 by p300/CBP coactivators

  1997cited by this paper
• p300 is required for MyoD‐dependent cell cycle arrest and muscle‐specific gene transcription

  1997cited by this paper
• Transcriptional Coactivator p300 Stimulates Cell Type-specific Gene Expression in Cardiac Myocytes*

  1997cited by this paper
• Adenovirus E1A downregulates cJun- and JunB-mediated transcription by targeting their coactivator p300

  1996influential reference
• Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain.

  1996cited by this paper
• Human p300 Protein Is a Coactivator for the Transcription Factor MyoD (*)

  1996cited by this paper
• Differential activation of ERK, JNK/SAPK and P38/CSBP/RK map kinase family members during the cellular response to arsenite.

  1996cited by this paper
• Ras-dependent and Ras-independent activation pathways for the stress-activated-protein-kinase cascade.

  1996cited by this paper
• Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator (*)

  1996cited by this paper
• A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

  1996cited by this paper
• The CBP co-activator is a histone acetyltransferase

  1996cited by this paper
• Differential Interactions of the CREB/ATF Family of Transcription Factors with p300 and Adenovirus E1A*

  1996influential reference
• The CR1 and CR3 domains of the adenovirus type 5 E1A proteins can independently mediate activation of ATF-2

  1996cited by this paper
• The transcriptional coactivators p300 and CBP are histone acetyltransferases.

  1996cited by this paper
• The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains

  1995cited by this paper
• ATF‐2 is preferentially activated by stress‐activated protein kinases to mediate c‐jun induction in response to genotoxic agents.

  1995cited by this paper
• A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

  1995cited by this paper
• Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

  1995cited by this paper
• CBP‐induced stimulation of c‐Fos activity is abrogated by E1A.

  1995influential reference
• ATF‐2 contains a phosphorylation‐dependent transcriptional activation domain.

  1995cited by this paper
• Transcription factor ATF2 regulation by the JNK signal transduction pathway

  1995influential reference
• Phosphorylation of the adenovirus E1A‐associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells.

  1995influential reference
• Modulation of AP‐1/ATF transcription factor activity by the adenovirus‐e1a oncogene products

  1995cited by this paper
• Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

  1995cited by this paper
• Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation.

  1994cited by this paper
• Nuclear protein CBP is a coactivator for the transcription factor CREB

  1994influential reference
• Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

  1994cited by this paper
• Novel interactions between human T-cell leukemia virus type I Tax and activating transcription factor 3 at a cyclic AMP-responsive element

  1994cited by this paper
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

  1994cited by this paper
• Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

  1994influential reference
• The stress-activated protein kinase subfamily of c-Jun kinases

  1994cited by this paper
• Structural determinants outside of the leucine zipper influence the interactions of CREB and ATF-2: interaction of CREB with ATF-2 blocks E1a-ATF-2 complex formation.

  1993cited by this paper
• Heterodimer formation of cJun and ATF‐2 is responsible for induction of c‐jun by the 243 amino acid adenovirus E1A protein.

  1993cited by this paper
• In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response

  1993cited by this paper
• Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

  1993cited by this paper
• UV‐induced activation of AP‐1 involves obligatory extranuclear steps including Raf‐1 kinase.

  1993cited by this paper
• Phosphorylated CREB binds specifically to the nuclear protein CBP

  1993influential reference
• Adenovirus E1A negatively and positively modulates transcription of AP‐1 dependent genes by dimer‐specific regulation of the DNA binding and transactivation activities of Jun.

  1993cited by this paper
• Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation.

  1992cited by this paper
• ULTRAVIOLET‐RADIATION INDUCED c‐jun GENE TRANSCRIPTION: TWO AP‐1 LIKE BINDING SITES MEDIATE THE RESPONSE

  1992cited by this paper
• Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

  1992cited by this paper
• New pUC-derived cloning vectors with different selectable markers and DNA replication origins.

  1991cited by this paper
• Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

  1991cited by this paper
• Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

  1991cited by this paper
• Phosphorylation of c-jun mediated by MAP kinases

  1991influential reference
• New pUC-derived cloning vectors with different selectable markers and DNA replication origins.

  1991cited by this paper
• Rapid and preferential activation of the c-jun gene during the mammalian UV response

  1991cited by this paper
• The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.

  1991cited by this paper
• mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element

  1990cited by this paper
• A novel function of the transforming domain of E1a: repression of AP-1 activity.

  1990cited by this paper
• Differential effects of the adenovirus E1A oncogene on members of the AP-1 transcription factor family

  1990influential reference
• Suppression of human colorectal carcinoma cell growth by wild-type p53.

  1990cited by this paper
• A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein.

  1990cited by this paper
• Prolonged activation of jun and collagenase genes by tumour necrosis factor-α

  1989cited by this paper
• Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

  1988cited by this paper
• The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1.

  1988cited by this paper
• Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts

  1988cited by this paper
• Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation.

  1987cited by this paper
• Transformation of rat cells by DNA of human adenovirus 5.

  1973cited by this paper

• Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

  2020cites this paper
• Multiple domains in the 50kDa form of E4F1 regulate promoter-specific repression and E1A trans-activation.

  2020cites this paper
• JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses

  2019cites this paper
• Genome-Wide Analysis of Transcriptional Regulation via TAF1 Kinase

  2017cites this paper
• JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships

  2016cites this paper
• Control of the cell cycle and mitosis by phosphorylated activating transcription factor 2 and its homologue 7

  2015cites this paper
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  2014cites this paper
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  2012cites this paper
• Critical Role of N-terminal End-localized Nuclear Export Signal in Regulation of Activating Transcription Factor 2 (ATF2) Subcellular Localization and Transcriptional Activity*

  2012cites this paper
• Etablierung der Chromatin-Immunopräzipitation für in vivo Untersuchungen der Genregulation durch Transkriptionsfaktoren bei der Honigbiene Apis mellifera

  2011cites this paper
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  2011cites this paper
• Genome-wide assessment of differential roles for p300 and CBP in transcription regulation

  2010cites this paper
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  2008cites this paper
• Inhibition of fra1 by the JNK-Jun pathway can protect cells against genotoxic stress

  2008cites this paper
• Restriction to Fos family members of Trip6-dependent coactivation and glucocorticoid receptor-dependent trans-repression of activator protein-1.

  2008cites this paper
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  2008cites this paper
• Ap1-like Cis elements in the 5′-regulatory region of the human apolipoprotein A-I gene

  2008cites this paper
• Chapter Aberrant Polycystin-1 Expression results in Modifi cation of AP-1 Activity , whereas Wnt Signaling remains unaffected 2

  2006cites this paper
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  2004cites this paper
• Human Vaccinia-related Kinase 1 (VRK1) Activates the ATF2 Transcriptional Activity by Novel Phosphorylation on Thr-73 and Ser-62 and Cooperates with JNK*

  2004cites this paper
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  2004influential citation
• Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected*

  2004cites this paper
• Cascade of Distinct Histone Modifications during Collagenase Gene Activation

  2003cites this paper
• Transcriptional Activation of C/EBPβ Gene by c-Jun and ATF2

  2002cites this paper
• Transcriptional activation of C/EBPbeta gene by c-Jun and ATF2.

  2002cites this paper
• Growth factors can activate ATF2 via a two‐step mechanism: phosphorylation of Thr71 through the Ras–MEK–ERK pathway and of Thr69 through RalGDS–Src–p38

  2002cites this paper
• An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis.

  2002cites this paper
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  2002cites this paper
• Oct-1 Potentiates CREB-Driven Cyclin D1 Promoter Activation via a Phospho-CREB- and CREB Binding Protein-Independent Mechanism

  2002cites this paper
• Retinoblastoma protein interacts with ATF2 and JNK/p38 in stimulating the transforming growth factor-beta2 promoter.

  2001cites this paper
• A specific lysine in c‐Jun is required for transcriptional repression by E1A and is acetylated by p300

  2001cites this paper
• Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

  2001cites this paper
• Evaluation der Tumorsuppressoraktivität transformationsdefekter Adenovirus-Serotyp 5 E1A- Mutanten

  2000cites this paper
• Janus Kinase 2-dependent Activation of p38 Mitogen-activated Protein Kinase by Growth Hormone

  2000cites this paper
• The coactivators p300 and CBP have different functions during the differentiation of F9 cells

  1999cites this paper