Hepatoprotective effect of Pterocarpus marsupium against carbon tetrachloride induced damage in albino rats

Medicinal plants play a key role in human health care. Pterocarpus marsupium is one of the plants used in treatment of diabetes mellitus and the present study was aimed to assess hepatoprotective effect of the plant against CCl4 induced hepatotoxicity. Wistar albino rats were divided into four groups. Group I was normal control group; Group II, the hepatotoxic group was given CCl4 (2ml/kg body weight intraperitoneally); Groups III received CC14 + Plant extract (100 mg/kg b.w orally); Group IV received only the plant extract. Liver markers were assayed in serum and liver tissue. Levels of marker enzymes such as alanine transminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) and bilirubin were increased significantly in Group II. These enzymes were significantly decreased in Group III treated with plant extracts. The present investigation suggest that the plant had a good protective effect on CCl4 induced hepatic injury.

• Publication year

  2007

• Venue

  Ancient Science of Life

• Publication date

  2007-07-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  PMID 22557255PMCID 3330841
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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