Spatial patterns of mammalian brain aging: Distribution of cathepsin D–immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease

No abstract is available for this paper.

• Publication year

  2003

• Venue

  The Journal of comparative neurology

• Publication date

  2003-09-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cne.10795PMID 12900930
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• On areas of transition between entorhinal allocortex and temporal isocortex in the human brain. Normal morphology and lamina-specific pathology in Alzheimer's disease

  2004cited by this paper
• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Aspects of neurodegeneration in the canine brain.

  2002cited by this paper
• Intraneuronal advanced glycation endproducts in presenilin‐1 Alzheimer's disease

  2002cited by this paper
• Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease

  2002cited by this paper
• Neuronal and glial advanced glycation end product [Nepsilon-(carboxymethyl)lysine]] in Alzheimer's disease brains.

  2001cited by this paper
• Neurobiological Models of Aging in the Dog and Other Vertebrate Species

  2001cited by this paper
• Rapid induction of intraneuronal neurofibrillary tangles in apolipoprotein E-deficient mice

  2001cited by this paper
• Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques

  2001cited by this paper
• Density profiles of Alzheimer disease regional brain pathology for the huddinge brain bank: pattern recognition emulates and expands upon Braak staging.

  2000cited by this paper
• Regionally selective changes in brain lysosomes occur in the transition from young adulthood to middle age in rats.

  2000cited by this paper
• Vulnerability of Select Neuronal Types to Alzheimer's Disease

  2000cited by this paper
• Vascular and parenchymal Abeta deposition in the aging dog: correlation with behavior.

  2000cited by this paper
• Region-specific age at onset of β-amyloid in dogs☆ ☆

  2000cited by this paper
• Neuronal and glial advanced glycation end product [Nε-(carboxymethyl)lysine] in Alzheimer's disease brains

  2000cited by this paper
• Novel Cathepsin D Inhibitors Block the Formation of Hyperphosphorylated Tau Fragments in Hippocampus

  2000cited by this paper
• Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains.

  2000cited by this paper
• Region-specific age at onset of beta-amyloid in dogs.

  2000cited by this paper
• Neuronal loss and neurofibrillary degeneration in the hippocampal cortex in late‐onset sporadic Alzheimer's disease

  2000cited by this paper
• Expression profile of transcripts in Alzheimer's disease tangle‐bearing CA1 neurons

  2000cited by this paper
• Age-related Changes in the Brain of the Dog

  1999cited by this paper
• Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles.

  1999cited by this paper
• The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms.

  1999cited by this paper
• Cortical distribution of neurofibrillary tangles in Alzheimer's disease matches the pattern of neurons that retain their capacity of plastic remodelling in the adult brain.

  1998cited by this paper
• Alzheimer's disease – synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

  1998cited by this paper
• Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1‐42 pathogenesis

  1998cited by this paper
• Distribution of advanced glycation end products in the cerebellar neurons of dogs.

  1998cited by this paper
• Dendritic changes in Alzheimer's disease and factors that may underlie these changes.

  1998cited by this paper
• Neuropathology of preclinical and clinical lateonset Alzheimer's disease

  1998cited by this paper
• Deposition of amyloid beta protein (A beta) subtypes [A beta 40 and A beta 42(43)] in canine senile plaques and cerebral amyloid angiopathy.

  1997cited by this paper
• Advanced glycation endproducts in ageing and Alzheimer's disease.

  1997cited by this paper
• Degradation of Tau by Lysosomal Enzyme Cathepsin D: Implication for Alzheimer Neurofibrillary Degeneration

  1997cited by this paper
• Deposition of amyloid β protein (Aβ) subtypes [Aβ40 and Aβ42(43)] in canine senile plaques and cerebral amyoloid angiopathy

  1997cited by this paper
• New insights into the neuropathology and cell biology of Alzheimer's disease.

  1997cited by this paper
• Cytosolic Proteolysis of τ by Cathepsin D in Hippocampus Following Suppression of Cathepsins B and L

  1996cited by this paper
• The role of the Maillard reaction in other pathologies: Alzheimer's disease.

  1996cited by this paper
• Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine.

  1996cited by this paper
• Neurofibrillary pathology--correlation with hippocampal formation atrophy in Alzheimer disease.

  1996cited by this paper
• Role of the Maillard Reaction in Diabetes Mellitus and Diseases of Aging

  1996cited by this paper
• The origin of amyloid in cerebral vessels of aged dogs.

  1995cited by this paper
• A topographical study of senile plaques and neurofibrillary tangles in the hippocampi of patients with Alzheimer's disease and cognitively impaired patients with schizophrenia.

  1993cited by this paper
• Topographic relationship between senile plaques and cerebrovascular amyloidosis in the brain of aged dogs.

  1992cited by this paper
• Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease.

  1991cited by this paper
• The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease.

  1991cited by this paper
• Modified Bielschowsky and immunohistochemical studies on senile plaques in aged dogs.

  1991cited by this paper
• Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia.

  1987cited by this paper
• Neuron numbers and dendritic extent in normal aging and Alzheimer's disease.

  1987cited by this paper
• Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia

  1977cited by this paper
• Distribution of cerebral degeneration in Alzheimer's disease

  1976cited by this paper

• LAMTOR1 regulates dendritic lysosomal positioning in hippocampal neurons through TRPML1 inhibition

  2024cites this paper
• Proteases as prognostic markers in human and canine cancers

  2017cites this paper
• Reconsider Alzheimer's disease by the 'calpain-cathepsin hypothesis'--a perspective review.

  2013cites this paper
• Cholesterol and Copper Affect Learning and Memory in the Rabbit

  2013cites this paper
• Dogs with cognitive dysfunction syndrome: a natural model of Alzheimer's disease.

  2012cites this paper
• New insights into the altered fibronectin matrix and extrasynaptic transmission in the aging brain

  2011cites this paper
• Implications of age and diet on canine cerebral cortex transcription.

  2009cites this paper
• Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

  2009cites this paper
• Upregulation of cathepsin S in the aging and pathological nervous system of mice.

  2008cites this paper
• Autophagic-Lysosomal Dysfunction and Neurodegeneration in Niemann-Pick Type C Mice: Lipid Starvation or Indigestion?

  2007cites this paper
• Differential expression of cathepsin X in aging and pathological central nervous system of mice.

  2007cites this paper
• Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease.

  2006cites this paper
• Cytoarchitectonic organization of the entorhinal cortex of the canine brain.

  2006cites this paper
• Synaptic plasticity in early aging.

  2006cites this paper
• Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study.

  2005cites this paper
• Proteolytic mechanisms in necrotic cell death and neurodegeneration

  2005cites this paper
• Cellular Responses to Protein Accumulation Involve Autophagy and Lysosomal Enzyme Activation

  2005cites this paper
• Lipofuscin and aging: a matter of toxic waste.

  2005cites this paper
• γ‐aminobutyric acidergic interneuron vulnerability to aging in canine prefrontal cortex

  2004cites this paper
• Distribution of ACTH immunoreactivity in the diencephalon and the brainstem of the dog.

  2004cites this paper
• Lysosomes and Brain Aging in Mammals

  2003cites this paper
• Anti-Aging Medicine LiteratureWatch

  2003cites this paper
• Gene Expression Profiling of Aging in Multiple Mouse Strains: Identification of Aging Biomarkers and Impact of Dietary Antioxidants

  year unknowncites this paper