Rapid Deletional Peripheral CD8 T Cell Tolerance Induced by Allogeneic Bone Marrow: Role of Donor Class II MHC and B Cells1

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Immunology

• Publication date

  2008-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.181.6.4371PMID 18768896PMCID PMC2628539
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• HLA-mismatched renal transplantation without maintenance immunosuppression.

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• CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase.

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• Myeloma Responses and Tolerance Following Combined Kidney and Nonmyeloablative Marrow Transplantation: In Vivo and In Vitro Analyses

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• Induction of Tolerance by Exosomes and Short‐Term Immunosuppression in a Fully MHC‐Mismatched Rat Cardiac Allograft Model

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• Langerhans cells arise from monocytes in vivo

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• Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD)

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• Early regulation of CD8 T cell alloreactivity by CD4+CD25– T cells in recipients of anti‐CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor‐reactive CD8+ T cells, precluding a role for sustained regulation

  2005cited by this paper
• Tolerosome‐induced oral tolerance is MHC dependent

  2005cited by this paper
• Induction of Central Tolerance by Mature T Cells1

  2004cited by this paper
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  2004cited by this paper
• Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells.

  2004cited by this paper
• Absence of clinical GVHD and the in vivo induction of regulatory T cells after transplantation of facilitating cells.

  2004cited by this paper
• Earlier Low‐Dose TBI or DST Overcomes CD8+ T‐Cell‐Mediated Alloresistance to Allogeneic Marrow in Recipients of Anti‐CD40L

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  2004cited by this paper
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  2003cited by this paper
• Lack of Role for CsA‐Sensitive or Fas Pathways in the Tolerization of CD4 T Cells Via BMT and Anti‐CD40L

  2003cited by this paper
• Tolerogenic dendritic cells.

  2003cited by this paper
• Regulation of T-cell functions by MHC class II self-presentation.

  2003cited by this paper
• B Cells Activated by Lipopolysaccharide, But Not By Anti-Ig and Anti-CD40 Antibody, Induce Anergy in CD8+ T Cells: Role of TGF-β11

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• Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

  2002cited by this paper
• Future strategies for tolerance induction: a comparative study between hematopoietic stem cells and macrophages.

  2002cited by this paper
• Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses.

  2002cited by this paper
• Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

  2002cited by this paper
• Induction Of Kidney Allograft Tolerance After Transient Lymphohematopoietic Chimerism In Patients With Multiple Myeloma And End-Stage Renal Disease1

  2002cited by this paper
• Direct and indirect cross-tolerance of alloreactive T cells by dendritic cells retained in the immature stage.

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• In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.

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• Lethal Murine Graft-Versus-Host Disease Induced by Donor ? / S Expressing T Cells With Specificity for Host Nonclassical Major Histocompatibility Complex Class Ib Antigens

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• Dissociation of Hemopoietic Chimerism and Allograft Tolerance After Allogeneic Bone Marrow Transplantation1

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• Costimulation Blockade, Busulfan, and Bone Marrow Promote Titratable Macrochimerism, Induce Transplantation Tolerance, and Correct Genetic Hemoglobinopathies with Minimal Myelosuppression1

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• DONOR T CELLS ARE NOT REQUIRED FOR INDUCTION OF ALLOGRAFT TOLERANCE IN MICE TREATED WITH ANTILYMPHOCYTE SERUM, RAPAMYCIN, AND DONOR BONE MARROW CELLS1

  2000cited by this paper
• Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance.

  1999cited by this paper
• Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance.

  1999cited by this paper
• Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance

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• B Cells Directly Tolerize CD8+ T Cells

  1998cited by this paper
• Donor resting B cells induce indefinite prolongation of fully allogeneic cardiac grafts when delivered with anti-immunoglobulin-D monoclonal antibody: evidence for tolerogenicity of donor resting B cells in vivo.

  1998cited by this paper
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  1996cited by this paper
• B lymphocytes secrete antigen-presenting vesicles

  1996cited by this paper
• Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys

  1995cited by this paper
• Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells.

  1994cited by this paper
• Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans

  1993cited by this paper
• Parameters of tolerance induction by antigen targeted to B lymphocytes.

  1993cited by this paper
• B cells turn off virgin but not memory T cells.

  1992cited by this paper
• Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens

  1992cited by this paper
• Immunologic tolerance to renal allografts after bone marrow transplants from the same donors.

  1991cited by this paper
• Small B Cells as Antigen Presenting Cells in the Induction of Tolerance to Soluble Protein Antigens: A Dissertation

  1991cited by this paper
• Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen

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• Positive and negative selection of an antigen receptor on T cells in transgenic mice

  1988cited by this paper
• Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes.

  1984cited by this paper
• Tolerance induction with bovine gamma globulin in mouse radiation chimaeras depends on macrophages.

  1974cited by this paper
• Tolerance induction with bovine γ globulin in mouse radiation chimaeras depends on macrophages

  1974cited by this paper

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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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• Hurdles to Transplant Tolerance Induction

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• Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials.

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