A point mutation in a cadherin gene, Cdh23, causes deafness in a novel mutant, Waltzer mouse niigata.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2001-04-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/BBRC.2001.4724PMID 11322776
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A high-resolution genetic map around waltzer on mouse Chromosome 10 and identification of a new allele of waltzer

  2009cited by this paper
• A genetic approach to understanding auditory function

  2001cited by this paper
• Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

  2001cited by this paper
• Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D

  2001cited by this paper
• A major gene affecting age-related hearing loss is common to at least ten inbred strains of mice.

  2000cited by this paper
• Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

  2000cited by this paper
• Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

  2000cited by this paper
• Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses.

  1999cited by this paper
• A novel type of myosin encoded by the mouse deafness gene shaker-2.

  1998cited by this paper
• Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3.

  1998cited by this paper
• Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

  1998cited by this paper
• Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.

  1997cited by this paper
• A comprehensive genetic map of the mouse genome

  1996cited by this paper
• Genes responsible for human hereditary deafness: symphony of a thousand

  1996cited by this paper
• Defective myosin VIIA gene responsible for Usher syndrome type IB

  1995cited by this paper
• A type VII myosin encoded by the mouse deafness gene shaker-1

  1995cited by this paper
• Cadherins: a molecular family important in selective cell-cell adhesion.

  1990cited by this paper
• Genetic variants and strains of the laboratory mouse

  1989cited by this paper

• Cdh23 Gene Mutation–Induced Vestibular Dysfunction in Mice: Abnormal Stereocilia Bundle and Otolith Development and Activation of p53/FoxO Signaling Pathway

  2025cites this paper
• Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context

  2024cites this paper
• A novel copy number variant in the murine Cdh23 gene gives rise to profound deafness and vestibular dysfunction

  2024cites this paper
• Retinal cadherins and the retinal cadherinopathies: Current concepts and future directions.

  2022cites this paper
• Development and evolution of the vestibular apparatuses of the inner ear

  2021cites this paper
• Phenotypic differences in the inner ears of CBA/CaJ and C57BL/6J mice carrying missense and single base pair deletion mutations in the Cdh23 gene

  2021influential citation
• Specific functions of Exostosin-like 3 (EXTL3) gene products

  2020cites this paper
• Chemical chaperone 4-phenylbutyrate prevents hearing loss and cochlear hair cell death in Cdh23erl/erl mutant mice

  2019cites this paper
• Discovery of CDH23 as a Significant Contributor to Progressive Postlingual Sensorineural Hearing Loss in Koreans

  2016cites this paper
• Differential effects of Cdh23(753A) on auditory and vestibular functional aging in C57BL/6J mice.

  2016cites this paper
• and Experience-Dependent Regulation Superior Olive Activate TRP-Like Channels: Age- Metabotropic Glutamate Receptors in the Lateral

  2015cites this paper
• Using injectoporation to deliver genes to mechanosensory hair cells

  2014cites this paper
• Compound Heterozygosity of the Functionally Null Cdh23v-ngt and Hypomorphic Cdh23ahl Alleles Leads to Early-onset Progressive Hearing Loss in Mice

  2013cites this paper
• Eeyore: A Novel Mouse Model of Hereditary Deafness

  2013cites this paper
• Sensing sound: molecules that orchestrate mechanotransduction by hair cells.

  2012cites this paper
• Genetics of Hearing and Deafness

  2012cites this paper
• Usher Syndrome: Genes, Proteins, Models, Molecular Mechanisms, and Therapies

  2012cites this paper
• Advantages of a mouse model for human hearing impairment.

  2012cites this paper
• Bcl11b heterozygosity leads to age-related hearing loss and degeneration of outer hair cells of the mouse cochlea.

  2011cites this paper
• An ENU-induced mutation of Cdh23 causes congenital hearing loss, but no vestibular dysfunction, in mice.

  2011cites this paper
• The Sound of Silence: Mouse Models for Hearing Loss

  2011cites this paper
• A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs

  2010cites this paper
• Deafness and retinal degeneration in a novel USH1C knock‐in mouse model

  2010cites this paper
• Cochlear Transduction and the Molecular Basis of Auditory Pathology

  2010cites this paper
• A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells

  2009cites this paper
• Harmonin mutations cause mechanotransduction defects in cochlear hair cells.

  2009cites this paper
• Truncated P‐cadherin is produced in oral squamous cell carcinoma

  2008cites this paper
• Mouse models to study inner ear development and hereditary hearing loss.

  2007cites this paper
• Metabotropic glutamate receptors in the lateral superior olive activate TRP-like channels: age- and experience-dependent regulation.

  2007cites this paper
• Distribution and frequencies of CDH23 mutations in Japanese patients with non‐syndromic hearing loss

  2007cites this paper
• Auditory transduction in the mouse

  2007cites this paper
• Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts.

  2006cites this paper
• Fates of Cdh23/CDH23 with mutations affecting the cytoplasmic region

  2006cites this paper
• Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia

  2004cites this paper
• Ahl3, a third locus on mouse chromosome 17 affecting age-related hearing loss.

  2004cites this paper
• CHAPTER 4 – Mouse Genomics

  2004cites this paper
• Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells

  2004cites this paper
• Mutations in the calcium-binding motifs of CDH23 and the 35delG mutation in GJB2 cause hearing loss in one family

  2003cites this paper
• Structure and innervation of the cochlea.

  2003cites this paper
• Recent Advances in the Understanding of Syndromic Forms of Hearing Loss

  2003cites this paper
• The cadherin superfamily in neural development: diversity, function and interaction with other molecules.

  2003cites this paper
• Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea

  2003cites this paper
• Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice.

  2002cites this paper
• Role of cadherins in Ca2+-mediated cell adhesion and inherited photoreceptor degeneration.

  2002cites this paper
• Continuing to break the sound barrier: genes in hearing.

  2002cites this paper
• Photoreceptors and Calcium

  2002cites this paper
• Mouse models for human genetic deafness

  2001cites this paper
• Mechanisms that regulate mechanosensory hair cell differentiation.

  2001cites this paper
• MACF1 gene structure: a hybrid of plectin and dystrophin

  2001cites this paper
• Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23).

  2001cites this paper