Differential Regulatory Role of Pituitary Adenylate Cyclase–Activating Polypeptide in the Serum-Transfer Arthritis Model

B. Botz,K. Bölcskei,L. Kereskai,M. Kovács,T. Németh,K. Szigeti,I. Horváth,D. Máthé,N. Kovács,H. Hashimoto,D. Reglodi,J. Szolcsányi,E. Pintér,A. Mócsai,Z. Helyes

Published 2014 in Arthritis & Rheumatology

ABSTRACT

Pituitary adenylate cyclase–activating polypeptide (PACAP) expressed in capsaicin‐sensitive sensory neurons and immune cells has divergent functions in inflammatory and pain processes. This study was undertaken to investigate the involvement of PACAP in a mouse model of rheumatoid arthritis.

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