SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

Tau hyperphosphorylation and neurofibrillary tangles are histopathologic hallmarks of tauopathies. Histamine H3‐receptor antagonists have been proposed to reduce tau hyperphosphorylation in preclinical models.

• Publication year

  2016

• Venue

  Alzheimer's & Dementia

• Publication date

  2016-11-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.trci.2016.10.002PMID 29067314PMCID 5651361
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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