Effects of hippocampus‐sparing resections in the temporal lobe: Hippocampal atrophy is associated with a decline in memory performance

K. Wagner,Karin Gau,B. Metternich,M. Geiger,Anne‐Sophie Wendling,N. E. Kadish,G. Reuner,H. Mayer,I. Mader,J. Beck,J. Zentner,H. Urbach,A. Schulze-Bonhage,C. Kaller,N. Foit

Published 2020 in Epilepsia

ABSTRACT

In patients with temporal lobe epilepsy (TLE) with a nonlesional and nonepileptogenic hippocampus (HC), in order to preserve functionally intact brain tissue, the HC is not resected. However, some patients experience postoperative memory decline, possibly due to disruption of the extrahippocampal memory network and secondary hippocampal volume (HV) loss. The purpose of this study was to determine the extent of hippocampal atrophy ipsilateral and contralateral to the side of the surgery and its relation to memory outcomes.

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