Characterization of endomorphin-1 and -2 on [35S]GTPgammaS binding in the mouse spinal cord.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  European Journal of Pharmacology

• Publication date

  1998-06-26

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0014-2999(98)00395-1PMID 9721032
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Immunoreactivity for endomorphin‐2 occurs in primary afferents in rats and monkey

  1998cited by this paper
• Evidence for the existence of the beta-endorphin-sensitive "epsilon-opioid receptor" in the brain: the mechanisms of epsilon-mediated antinociception.

  1998cited by this paper
• Evidence for the Existence of the β-Endorphin-Sensitive “ε-Opioid Receptor” in the Brain: The Mechanisms of ε-Mediated Antinociception

  1998cited by this paper
• A potent and selective endogenous agonist for the µ-opiate receptor

  1997cited by this paper
• A potent and selective endogenous agonist for the mu-opiate receptor.

  1997cited by this paper
• mu-Opioid receptor-stimulated guanosine-5'-O-(gamma-thio)-triphosphate binding in rat thalamus and cultured cell lines: signal transduction mechanisms underlying agonist efficacy.

  1997cited by this paper
• Spinal analgesic actions of the new endogenous opioid peptides endomorphin‐1 and ‐2

  1997cited by this paper
• Differences in G-protein activation by mu- and delta-opioid, and cannabinoid, receptors in rat striatum.

  1996cited by this paper
• Differences in G-protein activation by μ-and δ-opioid, and cannabinoid, receptors in rat striatum

  1996cited by this paper
• Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications.

  1995cited by this paper
• Cloning and characterization of the promoter region of the mouse mu opioid receptor gene.

  1995cited by this paper
• Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord

  1995cited by this paper
• Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells.

  1995cited by this paper
• Molecular cloning and functional expression of a mu opioid receptor from rat brain

  1994cited by this paper
• Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.

  1993cited by this paper
• Molecular cloning and functional expression of a mu-opioid receptor from rat brain.

  1993cited by this paper
• Mu antagonist and kappa agonist properties of beta-funaltrexamine (beta-FNA) in vivo: long-lasting spinal analgesia in mice.

  1990cited by this paper

• The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder

  2022cites this paper
• Intrathecal morphine-3-glucuronide-induced nociceptive behavior via Delta-2 opioid receptors in the spinal cord

  2016cites this paper
• Endomorphin-1 and Endomorphin-2: Involvement of Endogenous μ-Opioid Receptor Ligands in Analgesia, Antinociceptive Tolerance, Antianalgesia, and Hyperalgesia

  2014cites this paper
• Chapter 212 – Endomorphins

  2013cites this paper
• Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor

  2012cites this paper
• Recent Advances in Endomorphin Engineering

  2010cites this paper
• Endomorphin 1‐ and Endomorphin 2‐Containing Neurons in Nucleus Tractus Solitarii Send Axons to the Parabrachial Nuclei in the Rat

  2009cites this paper
• The Spinal Antinociceptive Effects of Endomorphins in Rats: Behavioral and G Protein Functional Studies

  2008cites this paper
• Antiinflammatory role of endomorphins in osteoarthritis, rheumatoid arthritis, and adjuvant-induced polyarthritis.

  2008cites this paper
• Endomorphin analogs containing alicyclic ß-amino acids: influence on conformation and pharmacological profile

  2008cites this paper
• From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides.

  2007cites this paper
• Endomorphins as Endogenous Peptides for μ-Opioid Receptor: Their Differences in the Pharmacological and Physiological Characters

  2006cites this paper
• Potent in vivo antinociception and opioid receptor preference of the novel analogue [Dmt1]endomorphin-1.

  2006cites this paper
• Partial and full agonism in endomorphin derivatives: comparison by null and operational model.

  2006cites this paper
• Differential Mechanisms of Antianalgesia Induced by Endomorphin-1 and Endomorphin-2 in the Ventral Periaqueductal Gray of the Rat

  2005cites this paper
• Endomorphin 1[psi] and endomorphin 2[psi], endomorphins analogues containing a reduced (CH2NH) amide bond between Tyr1 and Pro2, display partial agonist potency but significant antinociception.

  2005cites this paper
• The opioid properties of endomorphins in isolated organs and rat brain slices Ph . D . dissertation

  2004cites this paper
• Differential Conditioned Place Preference Responses to Endomorphin-1 and Endomorphin-2 Microinjected into the Posterior Nucleus Accumbens Shell and Ventral Tegmental Area in the Rat

  2004cites this paper
• Increased release of immunoreactive dynorphin A1-17 from the spinal cord after intrathecal treatment with endomorphin-2 in anesthetized rats.

  2004cites this paper
• Binding and Activity of Opioid Ligands at the Cloned Human Delta, Mu, and Kappa Receptors

  2003cites this paper
• Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene.

  2003cites this paper
• Acute antinociceptive tolerance and partial cross-tolerance to endomorphin-1 and endomorphin-2 given intrathecally in the mouse.

  2003cites this paper
• Prolactin Releasing Peptide Has High Affinity and Efficacy at Neuropeptide FF2 Receptors

  2003cites this paper
• Neuropeptides and sp inal antinoc iception : studies on ga lanin , noc iceptin and endo morphin

  2003cites this paper
• F rom the Department of Laboratory Medicine, D ivision of Clinical Neurophysiology, K arolinska Institutet, Stockholm, Sweden N europeptides and spinal antinociception: s tudies on galanin, nociceptin and endomorphin

  2003cites this paper
• Intrathecal treatment with 6-hydroxydopamine or 5,7-dihydroxytryptamine blocks the antinociception induced by endomorphin-1 and endomorphin-2 given intracerebroventricularly in the mouse.

  2003cites this paper
• Dynorphinergic Mechanism Mediating Endomorphin-2-Induced Antianalgesia in the Mouse Spinal Cord

  2003cites this paper
• Neuropeptides and spinal antinociception : Studies on galanin, nociceptin and endomorphin

  2003cites this paper
• Loss of mu-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of mu-opioid receptor gene.

  2002cites this paper
• Differential mechanism of G-protein activation induced by endogenous mu-opioid peptides, endomorphin and beta-endorphin.

  2002cites this paper
• Spinal Pretreatment with Antisense Oligodeoxynucleotides against Exon-1, -4, or -8 of μ-Opioid Receptor Clone Leads to Differential Loss of Spinal Endomorphin-1-and Endomorphin-2-Induced Antinociception in the Mouse

  2002cites this paper
• Recent Advances in the Search for the μ-Opioidergic System: The Antinociceptive Properties of Endomorphin-1 and Endomorphin-2 in the Mouse

  2002cites this paper
• Acute antinociceptive tolerance and unidirectional cross-tolerance to endomorphin-1 and endomorphin-2 given intraventricularly in the rat.

  2002cites this paper
• Endomorphins and related opioid peptides.

  2002cites this paper
• d-Pro2-Endomorphin-1 andd-Pro2-Endomorphin-2, Respectively, Attenuate the Antinociception Induced by Endomorphin-1 and Endomorphin-2 Given Intrathecally in the Mouse

  2002cites this paper
• Endomorphin-induced motivational effect: differential mechanism of endomorphin-1 and endomorphin-2.

  2002cites this paper
• Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy.

  2001cites this paper
• MOTIVATIONAL EFFECTS INDUCED BY THE u-OPIOID RECEPTOR LIGANDS ENDOMORPHlN-1 AND -2 IN THE MOUSE

  2001cites this paper
• Differential antinociception induced by spinally administered endomorphin-1 and endomorphin-2 in the mouse.

  2001cites this paper
• Progesterone Blockade of Estrogen Activation of μ-Opioid Receptors Regulates Reproductive Behavior

  2001cites this paper
• Different motivational effects induced by the endogenous mu-opioid receptor ligands endomorphin-1 and -2 in the mouse.

  2001cites this paper
• Acute antinociceptive tolerance and asymmetric cross-tolerance between endomorphin-1 and endomorphin-2 given intracerebroventricularly in the mouse.

  2001cites this paper
• Up-regulation of spinal mu-opioid receptor function to activate G-protein by chronic naloxone treatment.

  2001cites this paper
• Partial agonistic action of endomorphins in the mouse spinal cord.

  2001cites this paper
• Preparation of specifically tritiated endomorphins

  2001cites this paper
• Effects of a mu-opioid receptor agonist on G-protein activation in streptozotocin-induced diabetic mice.

  2000cites this paper
• Effects of a μ-opioid receptor agonist on G-protein activation in streptozotocin-induced diabetic mice

  2000cites this paper
• G protein activation by endomorphins in the mouse periaqueductal gray matter.

  2000cites this paper
• Stereochemical requirements for receptor recognition of the mu-opioid peptide endomorphin-1.

  2000cites this paper
• Activation of G-proteins in the mouse pons/medulla by beta-endorphin is mediated by the stimulation of mu- and putative epsilon-receptors.

  2000cites this paper
• Actions of endomorphins on synaptic transmission of Adelta-fibers in spinal cord dorsal horn neurons.

  2000cites this paper
• Differential mechanisms mediating descending pain controls for antinociception induced by supraspinally administered endomorphin-1 and endomorphin-2 in the mouse.

  2000cites this paper
• Differential involvement of mu(1)-opioid receptors in endomorphin- and beta-endorphin-induced G-protein activation in the mouse pons/medulla.

  2000cites this paper
• Endomorphin-1 and endomorphin-2: pharmacology of the selective endogenous mu-opioid receptor agonists.

  2000cites this paper
• μ‐opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR‐1

  1999cites this paper
• Region-dependent G-protein activation by mu-, delta 1- and delta 2-opioid receptor agonists in the brain: comparison between the midbrain and forebrain.

  1999cites this paper
• Region-dependent G-protein activation by μ-, δ1- and δ2-opioid receptor agonists in the brain: Comparison between the midbrain and forebrain

  1999cites this paper
• The mu-opioid receptor gene-dose dependent reductions in G-protein activation in the pons/medulla and antinociception induced by endomorphins in mu-opioid receptor knockout mice.

  1999cites this paper
• Antinociceptive effect and enzymatic degradation of endomorphin-1 in newborn rat spinal cord.

  1999cites this paper
• Identification of the G‐protein‐coupled ORL1 receptor in the mouse spinal cord by [35S]‐GTPγS binding and immunohistochemistry

  1999cites this paper
• The μ-opioid receptor gene-dose dependent reductions in G-protein activation in the pons/medulla and antinociception induced by endomorphins in μ-opioid receptor knockout mice

  1999cites this paper
• Absence of G‐protein activation by μ‐opioid receptor agonists in the spinal cord of μ‐opioid receptor knockout mice

  1999cites this paper
• Acta Universitatis Upsaliensis Uppsala 2008

  year unknowncites this paper