Ghrelin increases vagally mediated gastric activity by central sites of action

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Neurogastroenterology and Motility

• Publication date

  2014-02-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1111/nmo.12261PMID 24261332PMCID PMC3907172
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• Microvascular specializations promoting rapid interstitial solute dispersion in nucleus tractus solitarius.

  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1982cited by this paper
• Gastroduodenal motor gradients in the dog after pyloroplasty.

  1976cited by this paper
• Studies on the inhibitory nervous control of gastric motility.

  1973cited by this paper
• Vago-vagal reflex relaxation of the stomach in the cat.

  1969cited by this paper
• Elicitation of reflex vagal relaxation of the stomach from pharynx and esophagus in the cat.

  1969cited by this paper
• Handbook of Physiology.

  1960cited by this paper

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