Not all therapeutic antibody isotypes are equal: the case of IgM versus IgG in Pertuzumab and Trastuzumab† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04722k

Firdaus Samsudin,J. Yeo,S. Gan,P. Bond

Published 2020 in Chemical Science

ABSTRACT

The IgM antibody isotype of Pertuzumab affords simultaneous binding to antigens, but similar binding in Trastuzumab is hindered by steric clashes.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-68 of 68 references · Page 1 of 1

CITED BY

Showing 1-30 of 30 citing papers · Page 1 of 1