15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) Induces Cell Death Through Caspase-independent Mechanism in A172 Human Glioma Cells

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Neurochemical Research

• Publication date

  2006-09-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s11064-006-9157-0
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A Peroxisome Proliferator-activated Receptor-γ Agonist, Troglitazone, Facilitates Caspase-8 and -9 Activities by Increasing the Enzymatic Activity of Protein-tyrosine Phosphatase-1B on Human Glioma Cells*

  2006cited by this paper
• CD40 Engagement Prevents Peroxisome Proliferator-Activated Receptor γ Agonist-Induced Apoptosis of B Lymphocytes and B Lymphoma Cells by an NF-κB-Dependent Mechanism1

  2005cited by this paper
• Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.

  2005cited by this paper
• 15-deoxy-Delta-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism.

  2005cited by this paper
• CD40 engagement prevents peroxisome proliferator-activated receptor gamma agonist-induced apoptosis of B lymphocytes and B lymphoma cells by an NF-kappaB-dependent mechanism.

  2005cited by this paper
• Prostaglandin D2 and J2 induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species

  2005cited by this paper
• The ubiquitin ligase ability of IAPs regulates apoptosis

  2005cited by this paper
• Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas.

  2005cited by this paper
• 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.

  2005cited by this paper
• The Nonthiazolidinedione Tyrosine-Based Peroxisome Proliferator-Activated Receptor γ Ligand GW7845 Induces Apoptosis and Limits Migration and Invasion of Rat and Human Glioma Cells

  2005cited by this paper
• Brain tumors

  2005cited by this paper
• Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

  2005cited by this paper
• Peroxisome proliferator-activated receptor-γ ligands inhibit TGF-β1-induced fibronectin expression in glomerular mesangial cells

  2004cited by this paper
• Differential effects of peroxisome proliferator activated receptor-γ (PPARγ) ligands in proximal tubular cells: Thiazolidinediones are partial PPARγ agonists

  2004cited by this paper
• Life and death decisions: the role of the IAPs in modulating programmed cell death

  2004cited by this paper
• Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells.

  2004cited by this paper
• Glitazones Differentially Regulate Primary Astrocyte and Glioma Cell Survival

  2004cited by this paper
• Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: thiazolidinediones are partial PPAR gamma agonists.

  2004cited by this paper
• Peroxisome proliferator-activated receptor γ (PPARγ) ligands as bifunctional regulators of cell proliferation

  2003cited by this paper
• Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation.

  2003cited by this paper
• Phosphorylation of PPARγ via active ERK1/2 leads to its physical association with p65 and inhibition of NF‐κβ

  2003cited by this paper
• Troglitazone‐induced intracellular oxidative stress in rat hepatoma cells: A flow cytometric assessment

  2003cited by this paper
• Peroxisome Proliferator-Activated Receptor-γ Activator 15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Neuroblastoma Cell Growth through Induction of Apoptosis: Association with Extracellular Signal-Regulated Kinase Signal Pathway

  2003influential reference
• Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta.

  2003cited by this paper
• Cellular response to oxidative stress: Signaling for suicide and survival *

  2002cited by this paper
• Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: a review.

  2002cited by this paper
• Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARγ

  2002cited by this paper
• Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.

  2002cited by this paper
• MAP Kinase Cascades Are Activated in Astrocytes and Preadipocytes by 15-Deoxy-Δ12–14-prostaglandin J2 and the Thiazolidinedione Ciglitazone through Peroxisome Proliferator Activator Receptor γ-independent Mechanisms Involving Reactive Oxygenated Species*

  2002cited by this paper
• 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells

  2002cited by this paper
• 15-Deoxy-Δ12,14-prostaglandin J2-induced apoptosis does not require PPARγ in breast cancer cells Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200224-JLR200

  2002cited by this paper
• Ligand activation of peroxisome proliferator-activated receptor γ induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity

  2002cited by this paper
• Peroxisome proliferator-activated receptor gamma (PPARγ) and its ligands: A review

  2002cited by this paper
• Quantitation of mitochondrial alterations associated with apoptosis.

  2002influential reference
• Peroxisome proliferator-activated receptor gamma and metabolic disease.

  2001cited by this paper
• 15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.

  2001cited by this paper
• PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth.

  2001cited by this paper
• Cyclopentenone Prostaglandins as Potential Inducers of Intracellular Oxidative Stress*

  2001cited by this paper
• Cyclopentenone prostaglandins: New insights on biological activities and cellular targets

  2001cited by this paper
• A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.

  2001cited by this paper
• Early de Novo Gene Expression Is Required for 15-Deoxy-Δ12,14-prostaglandin J2-induced Apoptosis in Breast Cancer Cells*

  2001cited by this paper
• Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease.

  2001cited by this paper
• 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.

  2001cited by this paper
• PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ∞ AND METABOLIC DISEASE

  2001cited by this paper
• PPARγ: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth*

  2001cited by this paper
• 15-Deoxy-Δ12,14-prostaglandin J2 and Thiazolidinediones Activate the MEK/ERK Pathway through Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells*

  2001cited by this paper
• 15-deoxy-Delta(12,14)PGJ(2) induces diverse biological responses via PPARgamma activation in cancer cells.

  2000cited by this paper
• Signal transduction by the JNK group of MAP kinases.

  2000cited by this paper
• 15-deoxy-Δ12,14PGJ2 induces diverse biological responses via PPARγ activation in cancer cells

  2000cited by this paper
• Troglitazone and related compounds: therapeutic potential beyond diabetes.

  2000cited by this paper
• Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-Δ12,14-prostaglandin J2 *

  1999cited by this paper
• Apoptosis in neurodegenerative diseases: the role of mitochondria.

  1999cited by this paper
• Molecular characterization of mitochondrial apoptosis-inducing factor

  1999cited by this paper
• The mitochondrial death/life regulator in apoptosis and necrosis.

  1998cited by this paper
• The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition*

  1998cited by this paper
• Differentiation and reversal of malignant changes in colon cancer through PPARγ

  1998cited by this paper
• Caspases: the executioners of apoptosis.

  1997cited by this paper
• Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

  1995cited by this paper
• A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.

  1995cited by this paper
• 15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ

  1995cited by this paper
• Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.

  1993cited by this paper
• Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors.

  1992cited by this paper
• Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

  1990cited by this paper

• Inhibition of hypoxic exosomal miR-423-3p decreases glioma progression by restricting autophagy in astrocytes

  2025cites this paper
• 15-Deoxy-Δ12,14-prostaglandin J2 induces apoptosis in human microvascular endothelial cells (HMEC-1)

  2025cites this paper
• Synthesis and Significance of Arachidonic Acid, a Substrate for Cyclooxygenases, Lipoxygenases, and Cytochrome P450 Pathways in the Tumorigenesis of Glioblastoma Multiforme, Including a Pan-Cancer Comparative Analysis

  2023cites this paper
• Oxidative Stress Inducers in Cancer Therapy: Preclinical and Clinical Evidence

  2023cites this paper
• A review on mPGES-1 inhibitors: From preclinical studies to clinical applications.

  2019cites this paper
• The Role of Eicosanoids in Alzheimer’s Disease

  2019cites this paper
• Novel SIRT1 inhibitor 15-deoxy-Δ12,14-prostaglandin J2 and its derivatives exhibit anticancer activity through apoptotic or autophagic cell death pathways in SKOV3 cells

  2018cites this paper
• Physiological and Pathological Roles of 15-Deoxy-Δ12,14-Prostaglandin J2 in the Central Nervous System and Neurological Diseases

  2017cites this paper
• Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy

  2016cites this paper
• 15-Deoxy-Δ12,14-prostaglandin J2 induces PPARγ- and p53-independent apoptosis in rabbit synovial cells.

  2014cites this paper
• Sulfur as a signaling nutrient through hydrogen sulfide.

  2014cites this paper
• H2S and its role in redox signaling.

  2014cites this paper
• The 2-Series Eicosanoids in Cancer: Future Targets for Glioma Therapy?

  2013cites this paper
• PGJ2 Provides Prolonged CNS Stroke Protection by Reducing White Matter Edema

  2012cites this paper
• Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer

  2012cites this paper
• Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, independently of PPARγ in human glioma cells.

  2012cites this paper
• 15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species.

  2011cites this paper
• Anticancer Effects of 15d-Prostaglandin-J2 in Wild-Type and Doxorubicin-Resistant Ovarian Cancer Cells: Novel Actions on SIRT1 and HDAC

  2011cites this paper
• Metabolism and Roles of Eicosanoids in Brain

  2011cites this paper
• Modulation of mammary cancer cell migration by 15-deoxy-delta(12,14)-prostaglandin J(2): implications for anti-metastatic therapy.

  2010cites this paper
• A Novel Role for MAP1 LC3 in Non-Autophagic Cytoplasmic Vacuolation Death of Cancer Cells

  2009cites this paper
• Apoptosis-inducing factor and colon cancer.

  2009cites this paper
• In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF.

  2009cites this paper
• The PPARγ Agonist Rosiglitazone Inhibits Glioma Cell Proliferation and Migration in vitro and Glioma Tumor Growth in vivo

  2009cites this paper
• Underlying Mechanism of Quercetin-induced Cell Death in Human Glioma Cells

  2008cites this paper
• Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells.

  2008cites this paper