Вариабельность сердечного ритма и состояние системной гемодинамики у взрослых с впервые возникшим нетравматическим эпилептическим приступом при орто-клиностатической нагрузке

The aim of the study was to investigate vegetative maintenance of the activity and state of systemic hemodynamics in patients with a first time, non-traumatic epileptic seizure during a tilt table test (TTT). Materials and methods . TTT was performed in 42 patients with absence of seizures and 78 patients having experienced unprovoked seizures. A control group included 70 patients with non-epileptic seizures with transient loss of consciousness (TLC), defined as syncope. The control group included 38 people without episodes of loss of consciousness in their medical history. The parameters of hemodynamics and heart rate variability (HRV) were investigated at all stages of the test. Results . In patients with absence of seizures, initial sympathicotonia was recorded along with a decrease in ergotropic activation in orthostasis. In patients with unprovoked seizures, a hypersympathicotonic response to the orthostatic test was detected in combination with impaired vagal overshoot in the clinostatic phase of the test. In patients with TLC, evidence of vegetative insufficiency in the vertical position was identified, with the indicators going back to the background values in the horizontal position. Conclusion . The revealed features of vegetative regulation in patients with absence of seizures and unprovoked seizures will allow to differentiate the mechanism of the first-time epileptic seizure more accurately.

• Publication year

  2020

• Venue

  Unknown venue

• Publication date

  2020-01-14

• Fields of study

  Medicine

• Identifiers
  DOI 10.20538/1682-0363-2019-4-44-54
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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