Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2006-10-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.0607669103PMID 17043230PMCID PMC1635118
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus.

  2006cited by this paper
• Complete Genome of Acute Rheumatic Fever-Associated Serotype M5 Streptococcus pyogenes Strain Manfredo

  2006cited by this paper
• Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events.

  2005cited by this paper
• Toward a genome-wide systems biology analysis of host-pathogen interactions in group A Streptococcus.

  2005cited by this paper
• Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity.

  2005cited by this paper
• Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response.

  2005cited by this paper
• Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques.

  2005cited by this paper
• Growth Characteristics of and Virulence Factor Production by Group A Streptococcus during Cultivation in Human Saliva

  2005cited by this paper
• Analysis of a Novel Prophage-encoded Group A Streptococcus Extracellular Phospholipase A2*

  2004cited by this paper
• ExoU is a potent intracellular phospholipase

  2004cited by this paper
• Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.

  2004cited by this paper
• The challenge of emerging and re-emerging infectious diseases

  2004cited by this paper
• Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections.

  2004cited by this paper
• The mechanism of action of the Pseudomonas aeruginosa‐encoded type III cytotoxin, ExoU

  2003cited by this paper
• Pseudomonas aeruginosa ExoU, a Toxin Transported by the Type III Secretion System, Kills Saccharomyces cerevisiae

  2003cited by this paper
• Array of M protein gene subtypes in 1064 recent invasive group A streptococcus isolates recovered from the active bacterial core surveillance.

  2003cited by this paper
• Prophage Induction and Expression of Prophage-EncodedVirulence Factors in Group A Streptococcus Serotype M3 StrainMGAS315

  2003cited by this paper
• Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.

  2003cited by this paper
• In Vivo Phospholipase Activity of the Pseudomonas aeruginosa Cytotoxin ExoU and Protection of Mammalian Cells with Phospholipase A2 Inhibitors*

  2003cited by this paper
• Genome sequence of a serotype M3 strain of group A Streptococcus: Phage-encoded toxins, the high-virulence phenotype, and clone emergence

  2002cited by this paper
• NAD+‐glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococci

  2002cited by this paper
• Epidemiology of invasive group a streptococcus disease in the United States, 1995-1999.

  2002cited by this paper
• Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks

  2002cited by this paper
• Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996.

  2002cited by this paper
• Cytolysin-mediated translocation (CMT): a functional equivalent of type III secretion in gram-positive bacteria.

  2001cited by this paper
• Distribution of streptococcal inhibitor of complement variants in pharyngitis and invasive isolates in an epidemic of serotype M1 group A Streptococcus infection.

  2001cited by this paper
• Complete genome sequence of an M1 strain of Streptococcus pyogenes

  2001cited by this paper
• Cytochrome c‐mediated caspase‐9 activation triggers apoptosis in Streptococcus pyogenes‐infected epithelial cells

  2001cited by this paper
• Pathogenesis of group A streptococcal infections.

  2000cited by this paper
• Group A Streptococcus Induces Apoptosis in Human Epithelial Cells

  1999cited by this paper
• Molecular comparison of group A streptococci of T1M1 serotype from invasive and noninvasive infections in Finland.

  1997cited by this paper
• Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.

  1997cited by this paper
• Invasive group A streptococcal infections in Ontario, Canada. Ontario Group A Streptococcal Study Group.

  1996cited by this paper
• Emerging Infections: Microbial Threats to Health in the United States

  1992cited by this paper

• Antibacterial Activities of Recombinant Phospholipase rSlaAYE1 from Streptococcus pyogenes ADUYE1.

  2026cites this paper
• Analysis of Streptococcus dysgalactiae subspecies equisimilis gene transcripts during experimental primate necrotizing myositis

  2025cites this paper
• Quantitative assessment of allergenic risks from flying catkins in urban and rural environments: Pollens, bacteria, and heavy metals.

  2025cites this paper
• Activity-Based Protein Profiling Identifies Klebsiella pneumoniae Serine Hydrolases with Potential Roles in Host-Pathogen Interactions

  2024cites this paper
• A novel phospholipase A2 is a core component of the typhoid toxin genetic islet

  2024cites this paper
• Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells

  2024cites this paper
• Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells

  2024cites this paper
• Streptococcus dysgalactiae subsp. equisimilis infection and its intersection with Streptococcus pyogenes

  2024cites this paper
• Analysis of Glycerol and Dihydroxyacetone metabolism in Enterococcus faecium.

  2021cites this paper
• Categorizing Sequences of Concern by Function To Better Assess Mechanisms of Microbial Pathogenesis

  2021cites this paper
• Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

  2021cites this paper
• Molecular subtyping and antimicrobial susceptibility of Streptococcus dysgalactiae subspecies equisimilis isolates from clinically diseased pigs

  2020cites this paper
• Characterization and genome analysis of B1 sub-cluster mycobacteriophage PDRPxv.

  2020cites this paper
• Streptococcus pyogenes genes that promote pharyngitis in primates.

  2020cites this paper
• Lipid Droplets: A Significant but Understudied Contributor of Host–Bacterial Interactions

  2019cites this paper
• Structural analysis of a Vibrio phospholipase reveals an unusual Ser–His–chloride catalytic triad

  2019cites this paper
• Crystal structure of VvPlpA from Vibrio vulnificus

  2019cites this paper
• Identification of novel genes associated with anti-phagocytic functions in Streptococcus equi subsp. zooepidemicus.

  2019cites this paper
• How to become a killer, or is it all accidental? Virulence strategies in oral streptococci

  2018cites this paper
• Comparative Genomics of Environmental and Clinical Burkholderia cenocepacia Strains Closely Related to the Highly Transmissible Epidemic ET12 Lineage

  2018cites this paper
• Phylogenetic signature of lateral exchange of genes for antibiotic production and resistance among bacteria highlights a pattern of global transmission of pathogens between humans and livestock.

  2018cites this paper
• The contribution of genetic variation of Streptococcus pneumoniae to the clinical manifestation of invasive pneumococcal disease

  2017cites this paper
• Prevalence of M75 Streptococcus pyogenes Strains Harboring slaA Gene in Patients Affected by Pediatric Obstructive Sleep Apnea Syndrome in Central Italy

  2017cites this paper
• Immunogenicity of phospholipase A2 toxins and their role in Streptococcus equi pathogenicity.

  2017cites this paper
• Glycerol metabolism and its implication in virulence in Mycoplasma.

  2017cites this paper
• Streptococcus pyogenes Phospholipase A2 Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice

  2017influential citation
• Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique

  2016cites this paper
• Production and functional characterization of recombinant Streptococcus equi phospholipase A2 toxins SlaA and SlaB

  2016cites this paper
• Streptococcus pyogenes adhesion and colonization

  2016influential citation
• Bacterial Sphingomyelinases and Phospholipases as Virulence Factors

  2016influential citation
• The Streptococcus pyogenes orphan protein tyrosine phosphatase, SP‐PTP, possesses dual specificity and essential virulence regulatory functions

  2015influential citation
• Distribution of emm types among group A Streptococcus isolates from children in Korea.

  2015cites this paper
• Membrane-damaging and cytotoxic sphingomyelinases and phospholipases

  2015cites this paper
• Serotype M3 and M28 Group A Streptococci Have Distinct Capacities to Evade Neutrophil and TNF-α Responses and to Invade Soft Tissues

  2015cites this paper
• Hijacking and Use of Host Lipids by Intracellular Pathogens

  2015cites this paper
• Characterisation of group A streptococcal innate immune resistance and host response mechanisms

  2014cites this paper
• Functional analysis of a lipolytic protein encoded in phytoplasma phage based genomic island.

  2014cites this paper
• Étude épidémiologique des infections invasives et non invasives à Streptococcus pyogenes au CHU de Toulouse (2009-2013) : relations entre facteurs de virulence des souches, présentation clinique et issue des cas

  2014cites this paper
• Chapter 28 – Streptococcal Infections

  2014cites this paper
• Bacterial Activation of Type I Interferons

  2014cites this paper
• Type I Interferons in Immune Defense Against Streptococci

  2014cites this paper
• The Effects of Temperate Phage on Streptococcus Pneumoniae During Colonization

  2014cites this paper
• Phytoplasma Genomes: Evolution Through Mutually Complementary Mechanisms, Gene Loss and Horizontal Acquisition

  2014cites this paper
• Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

  2014cites this paper
• Strangles: taking steps towards eradication.

  2013cites this paper
• Group a streptococcal vaccine candidates: potential for the development of a human vaccine.

  2013cites this paper
• Host-Pathogen Interactions in Streptococcal Diseases

  2013cites this paper
• Neutral Genomic Microevolution of a Recently Emerged Pathogen, Salmonella enterica Serovar Agona

  2013cites this paper
• The effect of a natural covS mutation on virulence factor expression and innate immune evasion in a hypervirulent strain of group A streptococcus

  2013cites this paper
• Case Report Mystery or Misery? Primary Group A Streptococcal Peritonitis in Women:

  2013cites this paper
• Streptococcus zooepidemicus and Streptococcus equi evolution: the role of CRISPRs.

  2013cites this paper
• Identification of New Sphingomyelinases D in Pathogenic Fungi and Other Pathogenic Organisms

  2013cites this paper
• Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis

  2013cites this paper
• Current insights in invasive group A streptococcal infections in pediatrics

  2012cites this paper
• Mechanizmy wirulencji Streptococcus pyogenes

  2012cites this paper
• Vibrio harveyi phages: Isolation, characterization and evaluation of their potential as phage therapeutics on Vibrio harveyi in shrimp hatcheries

  2012cites this paper
• Investigation of the molecular basis of virulence of Streptococcus equi

  2012cites this paper
• Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation

  2012cites this paper
• Pathogenesis of group A streptococcal infections.

  2012cites this paper
• Superantigens in group A streptococcus gene diversity and humoral immune response

  2011cites this paper
• Comparison of rhesus and cynomolgus macaques in a Streptococcus pyogenes infection model for vaccine evaluation.

  2011cites this paper
• Streptococcus equi: a pathogen restricted to one host.

  2011cites this paper
• Novel phospholipases A of Pseudomonas aeruginosa: biochemical characterisation and cellular localisation

  2011cites this paper
• Virulence of serotype M3 Group A Streptococcus strains in wax worms (Galleria mellonella larvae)

  2011cites this paper
• Invasive group A, C and G streptococcal disease in western Norway: virulence gene profiles, clinical features and outcomes.

  2011cites this paper
• Multilocus variable number tandem repeat analysis (MLVA) of Streptococcus pyogenes.

  2011cites this paper
• Group A Streptococcus virulence and host factors in two toddlers with rheumatic fever following toxic shock syndrome.

  2010cites this paper
• emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway

  2010cites this paper
• Functional Characterization of a Phospholipase A2 Homolog from Rickettsia typhi

  2010cites this paper
• Pyogenic streptococci--danger of re-emerging pathogens.

  2010cites this paper
• Moonlighting Glutamate Formiminotransferases Can Functionally Replace 5-Formyltetrahydrofolate Cycloligase*

  2010cites this paper
• Two cutinase‐like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function

  2010cites this paper
• Molecular pathogenesis of necrotizing fasciitis.

  2010cites this paper
• Lower respiratory tract infection in cynomolgus macaques (Macaca fascicularis) infected with group A Streptococcus.

  2010cites this paper
• Population Genetics of Streptococcus

  2010cites this paper
• The Role of Lysogenic Bacteriophage in Virulence and Survival of Streptococcus Pyogenes

  2010cites this paper
• Mystery or misery? Primary group A streptococcal peritonitis in women: case report.

  2010cites this paper
• Molecular Characterisation and virulence Profiles of Group A Streptococci causing Human Infection in a South Indian community.

  2009cites this paper
• Charakterisierung Patatin-ähnlicher Proteine des Lungenpathogens Legionella pneumophila

  2009influential citation
• Role of the Type III Secretion System in a Hypervirulent Lineage of Bordetella bronchiseptica

  2009cites this paper
• Differences among group A streptococcus epidemiological landscapes: consequences for M protein-based vaccines?

  2009cites this paper
• A Novel Integrative Conjugative Element Mediates Genetic Transfer from Group G Streptococcus to Other β-Hemolytic Streptococci

  2009cites this paper
• Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

  2009cites this paper
• Molecular mechanisms underlying group A streptococcal pathogenesis

  2009influential citation
• A decade of molecular pathogenomic analysis of group A Streptococcus.

  2009cites this paper
• The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA

  2009cites this paper
• Comparative and Functional Genomic Analysis of Streptococcus Equi and Streptococcus Zooepidemicus : Identifying Novel Vaccine Targets

  2009cites this paper
• A non-human primate model of acute group a Streptococcus pharyngitis.

  2008cites this paper
• Biochemical and immunological mechanisms underlying differential interaction of superantigens with host immunogenetic factors in streptococcal sepsis

  2008cites this paper
• Adverse events following immunization: perception and evidence

  2007cites this paper
• New understanding of the group A Streptococcus pathogenesis cycle.

  2007cites this paper
• In vivo acquisition of prophage in Streptococcus pyogenes.

  2007cites this paper
• Secreted bacterial phospholipase A2 enzymes: better living through phospholipolysis.

  2007cites this paper
• Role of phages in the pathogenesis of Burkholderia, or 'Where are the toxin genes in Burkholderia phages?'.

  2007cites this paper
• Biotechnological challenges of phage therapy

  2007cites this paper
• Dynamics in Prophage Content of Invasive and Noninvasive M1 and M28 Streptococcus pyogenes Isolates in The Netherlands from 1959 to 1996

  2007cites this paper