Antiviral activity of natural and synthetic β-carbolines against dengue virus.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Antiviral Research

• Publication date

  2016-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.antiviral.2016.08.018PMID 27568370
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy.

  2016cited by this paper
• Antiviral activity of an N-allyl acridone against dengue virus

  2015cited by this paper
• Harmine blocks herpes simplex virus infection through downregulating cellular NF-κB and MAPK pathways induced by oxidative stress.

  2015cited by this paper
• Dengue virus entry and trafficking: perspectives as antiviral target for prevention and therapy

  2015cited by this paper
• Discovery of Dengue Virus NS4B Inhibitors

  2015cited by this paper
• Design, synthesis of new β-carboline derivatives and their selective anti-HIV-2 activity.

  2015cited by this paper
• Biomarkers of severe dengue disease – a review

  2015cited by this paper
• Recent advances in dengue pathogenesis and clinical management.

  2015cited by this paper
• Inhibition of Dengue Virus Replication by a Class of Small-Molecule Compounds That Antagonize Dopamine Receptor D4 and Downstream Mitogen-Activated Protein Kinase Signaling

  2014cited by this paper
• Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions

  2014cited by this paper
• Design, synthesis, and antiviral, fungicidal, and insecticidal activities of tetrahydro-β-carboline-3-carbohydrazide derivatives.

  2014cited by this paper
• Modulation of inflammation and pathology during dengue virus infection by p38 MAPK inhibitor SB203580.

  2014cited by this paper
• A dihydro-pyrido-indole potently inhibits HSV-1 infection by interfering the viral immediate early transcriptional events.

  2014cited by this paper
• MEK/ERK activation plays a decisive role in yellow fever virus replication: implication as an antiviral therapeutic target.

  2014cited by this paper
• Design, synthesis, anti-TMV, fungicidal, and insecticidal activity evaluation of 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid derivatives based on virus inhibitors of plant sources.

  2014cited by this paper
• Recent pharmacological developments in β-carboline alkaloid "harmaline".

  2013cited by this paper
• Pharmacological and therapeutic effects of Peganum harmala and its main alkaloids

  2013cited by this paper
• Inhibitory effect of doxycycline against dengue virus replication in vitro

  2013cited by this paper
• A review on medicinal importance, pharmacological activity and bioanalytical aspects of beta-carboline alkaloid ''Harmine''.

  2012cited by this paper
• Identification of cellular enhancing and restricting factors of dengue virus egress

  2011cited by this paper
• Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses*

  2011cited by this paper
• Differential effect of acute and persistent Junin virus infections on the nucleo-cytoplasmic trafficking and expression of heterogeneous nuclear ribonucleoproteins type A and B.

  2011cited by this paper
• JNK phosphorylation, induced during dengue virus infection, is important for viral infection and requires the presence of cholesterol.

  2010cited by this paper
• A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro

  2010cited by this paper
• Synthesis and evaluation of beta-carboline derivatives as inhibitors of human immunodeficiency virus.

  2010cited by this paper
• Antibacterial and antifungal activities of (beta)-carboline alkaloids of Peganum harmala (L) seeds and their combination effects.

  2010cited by this paper
• Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivatives.

  2010cited by this paper
• Efficient Assembly and Secretion of Recombinant Subviral Particles of the Four Dengue Serotypes Using Native prM and E Proteins

  2009cited by this paper
• Synthesis and antiviral activity of beta-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1).

  2009cited by this paper
• Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity.

  2008cited by this paper
• Synthesis and Evaluation of N-Substituted Acridones as Antiviral Agents against Haemorrhagic Fever Viruses

  2008cited by this paper
• Crosstalk between coagulation and inflammation during Dengue virus infection

  2008cited by this paper
• Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga.

  2008cited by this paper
• β-Carboline Alkaloids: Biochemical and Pharmacological Functions

  2007cited by this paper
• Flazinamide, a novel beta-carboline compound with anti-HIV actions.

  2007cited by this paper
• Interference in dengue virus adsorption and uncoating by carrageenans.

  2007cited by this paper
• beta-Carboline alkaloids: biochemical and pharmacological functions.

  2007cited by this paper
• The antiviral activity of sulfated polysaccharides against dengue virus is dependent on virus serotype and host cell.

  2005cited by this paper
• Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication.

  2005cited by this paper
• Design, synthesis and in vitro and in vivo antitumor activities of novel beta-carboline derivatives.

  2005cited by this paper
• Synthesis, acute toxicities, and antitumor effects of novel 9-substituted beta-carboline derivatives.

  2004cited by this paper
• Synthesis and Antimycobacterial Activity of Some β-Carboline Alkaloids

  2004cited by this paper
• Synthesis and antimycobacterial activity of some beta-carboline alkaloids.

  2004cited by this paper
• Antiviral and tumor cell antiproliferative SAR studies on tetracyclic eudistomins. II.

  1997cited by this paper

• Investigation of β-Carboline Alkaloid Harmaline Against Cyvirus cyprinidallo3 Infection In Vitro and In Vivo

  2025cites this paper
• Antibacterial and antiviral potential of harmalacidine hydrochloride, a β-carboline alkaloid, against respiratory tract pathogens: Staphylococcus aureus and H1N1 influenza virus

  2025cites this paper
• Natural Compounds and Their Analogs as Antivirals Against Dengue Virus: A Review

  2024cites this paper
• Resource distribution, pharmacological activity, toxicology and clinical drugs of β-Carboline alkaloids: An updated and systematic review.

  2024cites this paper
• Canthin-6-one analogs block Newcastle disease virus proliferation via suppressing the Akt and ERK pathways

  2024cites this paper
• In Vitro Effect of 9,9′-Norharmane Dimer against Herpes Simplex Viruses

  2024cites this paper
• Harmol used for the treatment of herpes simplex virus induced keratitis

  2024cites this paper
• Novel steroidal β-carboline derivatives as promising antibacterial candidates against methicillin-resistant Staphylococcus aureus.

  2024cites this paper
• A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A

  2023influential citation
• Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses

  2023cites this paper
• On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine

  2023cites this paper
• Berberine inhibitory action against zika and dengue viruses in cell cultures

  2023cites this paper
• Synthesis, characterization and biological activity of novel copper complexes containing a β-carboline derivative and amino acids.

  2023cites this paper
• 9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β

  2023cites this paper
• Homologous recombination technology generated recombinant pseudorabies virus expressing EGFP facilitates to evaluate its susceptibility to different cells and screen antiviral compounds.

  2022cites this paper
• Natural Resources for Human Health

  2022cites this paper
• Harmine, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium

  2022cites this paper
• Bioactive natural products in COVID-19 therapy

  2022cites this paper
• Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson’s models via regulating autophagy-lysosome pathway

  2022cites this paper
• Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products

  2022cites this paper
• Marine Natural Products as Leads against SARS-CoV-2 Infection

  2022cites this paper
• Preliminary identification of potential phytochemical components as antiviral agents against Dengue Virus 2: An in silico study

  2022cites this paper
• Antimicrobial Activity of a Repurposed Harmine-Derived Compound on Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates

  2022cites this paper
• Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy

  2021cites this paper
• Total Synthesis of 6-Hydroxymetatacarboline-d Discovered from Mycena metata via the Pictet–Spengler Reaction Followed by the Horner–Wadsworth–Emmons Reaction

  2021cites this paper
• Could Peganum harmala be effective in the treatment of COVID-19?

  2021cites this paper
• Photophysical properties of a β-Carboline Rhenium (I) complex. Solvent effects on excited states and their redox reactivity

  2021cites this paper
• 1-Formyl-β-carboline Derivatives Block Newcastle Disease Virus Proliferation through Suppressing Viral Adsorption and Entry Processes

  2021cites this paper
• Plant-derived alkaloids acting on dengue virus and their vectors: from chemistry to pharmacology.

  2021cites this paper
• Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature-Based Undivided Perspective

  2021cites this paper
• Indole - a promising pharmacophore in recent antiviral drug discovery.

  2020cites this paper
• Identification of the phytobioactive Polygonum cuspidatum as an antiviral source for restricting dengue virus entry

  2020cites this paper
• Pharmacological effects of harmine and its derivatives: a review

  2020cites this paper
• Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses.

  2020cites this paper
• Computational screening for potential drug candidates against the SARS-CoV-2 main protease

  2020cites this paper
• Recent update on the anti-infective potential of β-carboline analogs.

  2020cites this paper
• A systematic review on phytochemicals for the treatment of dengue

  2020cites this paper
• Machine Learning Model For Predicting Anti-Dengue Drugs: A Three-Dimensional Quantitative Structure–Activity Relationship (3D QSAR) Study

  2020cites this paper
• Synthesis of 1-(4-hydroxy-3-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid derivatives as mast cell stabilizers

  2020cites this paper
• Application of metal free aromatization to total synthesis of perlolyrin, flazin, eudistomin U and harmane

  2020cites this paper
• Direct (het)arylation of tetrahydroisoquinolines via a metal and oxidant free C(sp3)-H functionalization enabled three component reaction.

  2019cites this paper
• Synthetic modifications of carboline alkaloid harmine: synthesis of 8-substituted derivatives

  2019cites this paper
• [1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation

  2019cites this paper
• Recent update on anti-dengue drug discovery.

  2019cites this paper
• Inhibition of dengue viral infection by diasarone‐I is associated with 2’O methyltransferase of NS5

  2018cites this paper
• Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF‐&kgr;B pathway

  2018cites this paper
• Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections.

  2018cites this paper
• Design, synthesis, and biological evaluation of 2‐substituted‐2,3,4,9‐tetrahydrospiro‐β‐carboline‐3‐carboxylic acid derivatives as first‐in‐class mast cell stabilizers

  2018cites this paper
• Synthesis and investigations into the anticancer and antibacterial activity studies of β-carboline chalcones and their bromide salts.

  2018cites this paper
• 1(3)‐Formyl‐β‐carbolines: Potential Aldo‐X Precursors for the Synthesis of β‐Carboline‐Based Molecular Architectures

  2018cites this paper
• Iodine-catalyzed chemoselective dehydrogenation and aromatization of tetrahydro-β-carbolines: A short synthesis of Kumujian-C, Eudistomin-U, Norharmane, Harmane Harmalan and Isoeudistomine-M

  2018cites this paper
• Harmine and its derivatives: Biological activities and therapeutic potential in human diseases

  2018cites this paper
• An estrogen antagonist, cyclofenil, has anti-dengue-virus activity

  2018cites this paper
• β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities.

  2018cites this paper
• β-Carboline derivatives as novel antivirals for herpes simplex virus.

  2018cites this paper
• Role of mitogen-activated protein kinase signaling in the pathogenesis of dengue virus infection.

  2018cites this paper
• Synthesis of β-carbolines via a silver-mediated oxidation of tetrahydro-β-carbolines

  2017cites this paper
• Potential Antivirals: Natural Products Targeting Replication Enzymes of Dengue and Chikungunya Viruses

  2017cites this paper
• Intramolecular Csp2-Csp2 Friedel-Crafts Arylation: Substrate- and Condition-Controlled Divergent Synthesis of Fused-β-carbolines.

  2016cites this paper