mTORC2 critically regulates renal potassium handling.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Clinical Investigation

• Publication date

  2016-05-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI80304PMID 27043284PMCID PMC4855939
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dietary potassium and the renal control of salt balance and blood pressure

  2015cited by this paper
• mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.

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• In brief

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• mSIN1 Protein Mediates SGK1 Protein Interaction with mTORC2 Protein Complex and Is Required for Selective Activation of the Epithelial Sodium Channel*

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• Comment on: Kumar et al. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism. Diabetes 2010;59:1397–1406

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• Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium

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