Hetero diacylation of 1,1-diborylalkanes: Practical synthesis of 1,3-diketones

Abstract An efficient protocol for the synthesis of asymmetric 1,3-diketones was reported through diacylation of 1,1-diborylalkanes using two different acyl sources. In this transformation, an enolate boron species was initially formed by introducing an acyl group, then it was trapped by another acyl group to form 1,3-diketone. This method not only provided the gateway to obtain a series of 1,3-diketones, but also afforded an operationally simple and efficient access to pyrazoles and isoxazoles.

• Publication year

  2020

• Venue

  Chinese Chemical Letters

• Publication date

  2020-07-01

• Fields of study

  Chemistry

• Identifiers
  DOI 10.1016/j.cclet.2019.12.016
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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