A recyclable and highly stereoselective multi-fluorous proline catalyst for asymmetric aldol reactions

Abstract A recyclable fluorous proline catalyst with high stereoselectivity that functions as a catalyst for asymmetric aldol reactions is described. Its high stereoselectivity and facile recovery are achieved by employing a multi-fluorous tag attachment strategy. Although a gradual decrease was observed with respect to the catalytic activity, the catalyst can be separated from the reaction mixture by adsorption onto FluoroFlash® and can be reused in that form for a maximum of five times while maintaining a high stereoselectivity.2019 Elsevier Ltd. All rights reserved.

• Publication year

  2020

• Venue

  Tetrahedron Letters

• Publication date

  2020-03-26

• Fields of study

  Chemistry

• Identifiers
  DOI 10.1016/j.tetlet.2020.151657
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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