Microsatellite Instability, EMAST, and Morphology Associations with T Cell Infiltration in Colorectal Neoplasia

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Digestive Diseases and Sciences

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10620-011-1825-5PMID 21773681PMCID PMC3245369
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias.

  2010influential reference
• 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity.

  2010cited by this paper
• Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability

  2010cited by this paper
• Relationship of EMAST and Microsatellite Instability Among Patients with Rectal Cancer

  2010cited by this paper
• Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients

  2010cited by this paper
• Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome

  2010cited by this paper
• Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.

  2009cited by this paper
• Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.

  2008cited by this paper
• Colorectal cancer in inflammatory bowel disease.

  2008cited by this paper
• Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers. Authors' reply

  2008cited by this paper
• Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.

  2008cited by this paper
• Genomic and epigenetic instability in colorectal cancer pathogenesis.

  2008influential reference
• Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.

  2008influential reference
• Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

  2006influential reference
• Colon cancer and the immune system: the role of tumor invading T cells.

  2006cited by this paper
• Effector memory T cells, early metastasis, and survival in colorectal cancer.

  2005cited by this paper
• CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma.

  2003cited by this paper
• Frameshift peptide‐derived T‐cell epitopes: A source of novel tumor‐specific antigens

  2001cited by this paper
• CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.

  1998influential reference
• Prognostic value of tumour‐infiltrating lymphocytes (TILs) in colorectal cancer

  1997cited by this paper

• The Immune Environment in Colorectal Adenoma: A Systematic Review

  2025cites this paper
• Clinicopathological features and mutational landscape of colorectal cancer subgroups defined by MSI and EMAST status.

  2025cites this paper
• THE JEREMIAH METZGER LECTURE: ENVIRONMENTAL INFLUENCES ON COLORECTAL CANCER.

  2024cites this paper
• EMAST Type of Microsatellite Instability—A Distinct Entity or Blurred Overlap between Stable and MSI Tumors

  2023influential citation
• Racial and ethnic disparities in colorectal cancer incidence and mortality.

  2021cites this paper
• Left-sided colorectal cancer distinct in indigenous African patients compared to other ethnic groups in South Africa

  2021cites this paper
• Immunological Features with DNA Microsatellite Alterations in Patients with Colorectal Cancer.

  2020cites this paper
• Genetic Variants in the Regulatory T cell–Related Pathway and Colorectal Cancer Prognosis

  2020cites this paper
• EMAST frequency in colorectal cancer: a meta-analysis and literature review.

  2020cites this paper
• Is elevated microsatellite alterations at selected tetranucleotide repeats (EMAST)‐negative/MSI‐high colorectal cancer a distinct subtype of the disease?

  2020cites this paper
• Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer

  2020cites this paper
• EMAST status as a beneficial predictor of fluorouracil‐based adjuvant chemotherapy for Stage II/III colorectal cancer

  2020cites this paper
• The value of single-source dual-energy CT imaging for discriminating microsatellite instability from microsatellite stability human colorectal cancer

  2019cites this paper
• Combined Microsatellite Instability and Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) Might Be a More Promising Immune Biomarker in Colorectal Cancer.

  2019cites this paper
• TH9, TH17, and TH22 Cell Subsets and Their Main Cytokine Products in the Pathogenesis of Colorectal Cancer

  2019influential citation
• ELEVATED MICROSATELLITE ALTERATIONS AT SELECTED TETRA-NUCLEOTIDE REPEATS ( EMAST ) TESTING IN COLORECTAL CANCER USING THE COST-EFFECTIVE QIAXCEL ADVANCED PLATFORM

  2019cites this paper
• A new method for discovering EMAST sequences in animal models of cancer

  2018cites this paper
• Identification of PMN-released mutagenic factors in a co-culture model for colitis-associated cancer

  2018cites this paper
• MSI‐L/EMAST is a predictive biomarker for metastasis in colorectal cancer patients

  2018cites this paper
• Clinical and Genetic Factors to Inform Reducing Colorectal Cancer Disparitites in African Americans

  2018cites this paper
• Fusobacterium nucleatum Infection in Colorectal Cancer: Linking Inflammation, DNA Mismatch Repair and Genetic and Epigenetic Alterations

  2018cites this paper
• Personalised Genomics and Molecular Profiles in Colorectal Cancer: Towards Precision Cancer Care

  2017cites this paper
• Microsatellite Instability Pathway and EMAST in Colorectal Cancer

  2017cites this paper
• The colorectal cancer immune microenvironment and approach to immunotherapies.

  2017cites this paper
• Correlation of Blood T-Cells to Intratumoural Density and Location of CD3+ and CD8+ T-Cells in Colorectal Cancer.

  2017cites this paper
• Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.

  2016cites this paper
• Heterogeneity in gastric cancer and the impact on patient survival

  2016cites this paper
• Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.

  2016cites this paper
• The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis

  2016cites this paper
• Elevated microsatellite alterations at selected tetranucleotides in early‐stage colorectal cancers with and without high‐frequency microsatellite instability: same, same but different?

  2016cites this paper
• Screening for Colorectal Cancer in African Americans: Determinants and Rationale for an Earlier Age to Commence Screening

  2015cites this paper
• Outcome parameters in metastatic colorectal cancer

  2015cites this paper
• Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer.

  2015cites this paper
• EMAST Is Associated with a Poor Prognosis in Microsatellite Instable Metastatic Colorectal Cancer

  2015cites this paper
• Interleukin 6 alters localization of hMSH3, leading to DNA mismatch repair defects in colorectal cancer cells.

  2015cites this paper
• Integrative Omics Analysis Reveals Post-Transcriptionally Enhanced Protective Host Response in Colorectal Cancers with Microsatellite Instability

  2015cites this paper
• EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression

  2015cites this paper
• Systemic Analysis of Predictive Biomarkers for Recurrence in Colorectal Cancer Patients Treated with Curative Surgery

  2015cites this paper
• Correction: Influence of Race on Microsatellite Instability and CD8+ T Cell Infiltration in Colon Cancer

  2014cites this paper
• A dual-fluorescent reporter facilitates identification of thiol compounds that suppress microsatellite instability induced by oxidative stress.

  2014cites this paper
• Low Prevalence of Microsatellite Instability in Interval Gastric Cancers

  2014cites this paper
• Prevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer

  2014influential citation
• Influence of Race on Microsatellite Instability and CD8+ T Cell Infiltration in Colon Cancer

  2014cites this paper
• Excess of Proximal Microsatellite-Stable Colorectal Cancer in African Americans from a Multiethnic Study

  2014cites this paper
• Progressive Increase of Regulatory T Cells and Decrease of CD8+ T Cells and CD8+ T Cells/Regulatory T Cells Ratio during Colorectal Cancer Development

  2013cites this paper
• Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?

  2013cites this paper
• MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells

  2012cites this paper
• On the prognostic & predictive impact of immune cells system in colorectal cancer

  2012cites this paper
• Colorectal Cancer: Sailing with a T-Cell EMAST

  2011influential citation