Role of neighboring FMN side chains in the modulation of flavin reduction potentials and in the energetics of the FMN:apoprotein interaction in Anabaena flavodoxin.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Biochemistry

• Publication date

  2004-12-07

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI0483256PMID 15568803
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 2. Evidence for cooperative conformational changes involving tryptophan 60 in the interaction between the phosphate- and ring-binding subsites.

  2003cited by this paper
• How FMN Binds to Anabaena Apoflavodoxin

  2003cited by this paper
• Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.

  2003cited by this paper
• Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin.

  2002cited by this paper
• Anabaena sp. PCC 7119 Flavodoxin as Electron Carrier from Photosystem I to Ferredoxin-NADP+Reductase

  2002cited by this paper
• The PyMOL Molecular Graphics System

  2002cited by this paper
• Role of hydrogen bonding interactions to N(3)H of the flavin mononucleotide cofactor in the modulation of the redox potentials of the Clostridium beijerinckii flavodoxin.

  2001cited by this paper
• Alanine-scanning of the 50's loop in the Clostridium beijerinckii flavodoxin: evaluation of additivity and the importance of interactions provided by the main chain in the modulation of the oxidation-reduction potentials.

  2001cited by this paper
• Native hydrogen bonds in a molten globule: the apoflavodoxin thermal intermediate.

  2001cited by this paper
• Structures and comparison of the Y98H (2.0 A) and Y98W (1.5 A) mutants of flavodoxin (Desulfovibrio vulgaris).

  2001cited by this paper
• Cloning, sequencing and expression of the gene for flavodoxin from Megasphaera elsdenii and the effects of removing the protein negative charge that is closest to N(1) of the bound FMN.

  2000cited by this paper
• Dissecting the Energetics of the Apoflavodoxin-FMN Complex*

  2000cited by this paper
• Electron-nuclear double resonance and hyperfine sublevel correlation spectroscopic studies of flavodoxin mutants from Anabaena sp. PCC 7119.

  1999cited by this paper
• Potentiometric measurement of oxidation-reduction potentials.

  1999cited by this paper
• Comparisons of wild-type and mutant flavodoxins from Anacystis nidulans. Structural determinants of the redox potentials.

  1999influential reference
• pH-dependent spectroscopic changes associated with the hydroquinone of FMN in flavodoxins.

  1999cited by this paper
• The effects of pH and semiquinone formation on the oxidation-reduction potentials of flavin mononucleotide. A reappraisal.

  1999cited by this paper
• X-ray crystal structure of the Desulfovibrio vulgaris (Hildenborough) apoflavodoxin-riboflavin complex.

  1998cited by this paper
• Role of methionine 56 in the control of the oxidation-reduction potentials of the Clostridium beijerinckii flavodoxin: effects of substitutions by aliphatic amino acids and evidence for a role of sulfur-flavin interactions.

  1998cited by this paper
• Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants.

  1998cited by this paper
• Differential stabilization of the three FMN redox forms by tyrosine 94 and tryptophan 57 in flavodoxin from Anabaena and its influence on the redox potentials.

  1997cited by this paper
• One- and two-dimensional ESEEM spectroscopy of flavoproteins.

  1997cited by this paper
• Evaluation of the role of specific acidic amino acid residues in electron transfer between the flavodoxin and cytochrome c3 from Desulfovibrio vulgaris.

  1997cited by this paper
• SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

  1997cited by this paper
• Regulation of oxidation-reduction potentials through redox-linked ionization in the Y98H mutant of the Desulfovibrio vulgaris [Hildenborough] flavodoxin: direct proton nuclear magnetic resonance spectroscopic evidence for the redox-dependent shift in the pKa of Histidine-98.

  1997cited by this paper
• Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes.

  1997cited by this paper
• Crystal structure of flavodoxin from Desulfovibrio desulfuricans ATCC 27774 in two oxidation states.

  1996cited by this paper
• The cumulative electrostatic effect of aromatic stacking interactions and the negative electrostatic environment of the flavin mononucleotide binding site is a major determinant of the reduction potential for the flavodoxin from Desulfovibrio vulgaris [Hildenborough].

  1996cited by this paper
• Closure of a tyrosine/tryptophan aromatic gate leads to a compact fold in apo flavodoxin

  1996cited by this paper
• LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions.

  1995cited by this paper
• Electrostatic effects of surface acidic amino acid residues on the oxidation-reduction potentials of the flavodoxin from Desulfovibrio vulgaris (Hildenborough).

  1995cited by this paper
• Structure of the trigonal form of recombinant oxidized flavodoxin from Anabaena 7120 at 1.40 A resolution.

  1995cited by this paper
• Site-directed mutagenesis of tyrosine-98 in the flavodoxin from Desulfovibrio vulgaris (Hildenborough): regulation of oxidation-reduction properties of the bound FMN cofactor by aromatic, solvent, and electrostatic interactions.

  1994influential reference
• Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures.

  1993cited by this paper
• The primary structures of the flavodoxins from two strains of Desulfovibrio gigas. Cloning and nucleotide sequence of the structural genes.

  1992cited by this paper
• Electron Nuclear Double Resonance

  1992cited by this paper
• Structure of the oxidized long‐chain flavodoxin from anabaena 7120 at 2 å resolution

  1992cited by this paper
• Crystal structure of oxidized flavodoxin from a red alga Chondrus crispus refined at 1.8 A resolution. Description of the flavin mononucleotide binding site.

  1992cited by this paper
• Cloning and characterization of the flavodoxin gene from Desulfovibrio desulfuricans.

  1991cited by this paper
• Redox and flavin-binding properties of recombinant flavodoxin from Desulfovibrio vulgaris (Hildenborough).

  1991cited by this paper
• Oxidation-reduction potentials of ferredoxin-NADP+ reductase and flavodoxin from Anabaena PCC 7119 and their electrostatic and covalent complexes.

  1991cited by this paper
• Identification, sequence determination, and expression of the flavodoxin gene from Desulfovibrio salexigens.

  1990cited by this paper
• Tertiary structure of oxidized flavodoxin from an eukaryotic red alga Chondrus crispus at 2.35-A resolution. Localization of charged residues and implication for interaction with electron transfer partners.

  1990cited by this paper
• Structure and oxidation-reduction behavior of 1-deaza-FMN flavodoxins: modulation of redox potentials in flavodoxins.

  1990cited by this paper
• Nuclear-magnetic-resonance investigation of 15N-labeled flavins, free and bound to Megasphaera elsdenii apoflavodoxin.

  1984cited by this paper
• Some new ideas about the possible regulation of redox potentials in flavoprotein, with special reference to flavodoxins

  1984cited by this paper
• Structure of oxidized flavodoxin from Anacystis nidulans.

  1983cited by this paper
• Structure of the semiquinone form of flavodoxin from Clostridum MP. Extension of 1.8 A resolution and some comparisons with the oxidized state.

  1978cited by this paper
• Studies on the binding of FMN by apoflavodoxin from Peptostreptococcus elsdenii, pH and NaCl concentration dependence.

  1976cited by this paper
• The binding of riboflavin-5'-phosphate in a flavoprotein: flavodoxin at 2.0-Angstrom resolution.

  1973cited by this paper
• The Binding of Riboflavin-5′-Phosphate in a Flavoprotein: Flavodoxin at 2.0-Å Resolution

  1973cited by this paper
• Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein.

  1971cited by this paper
• Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein.

  1971cited by this paper
• Oxidation-reduction properties of flavodoxin from Peptostreptococcus elsdenii.

  1969cited by this paper
• Purification and characterization of flavodoxin from Peptostreptococcus elsdenii.

  1969cited by this paper
• A potentiometric study of the flavin semiquinone equilibrium.

  1968cited by this paper

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• Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease‐associated NQO1 enzyme *

  2022cites this paper
• Sequence Conservation Does Not Always Signify a Functional Imperative as Observed in the Nitroreductase Superfamily.

  2022cites this paper
• Assignments of 19F NMR resonances and exploration of dynamics in a long-chain flavodoxin.

  2021cites this paper
• Spin Densities in Flavin Analogs within a Flavoprotein.

  2016cites this paper
• Noncovalent interactions in biocomplexes

  2016influential citation
• The mechanism of water/ion exchange at a protein surface: a weakly bound chloride in Helicobacter pylori apoflavodoxin.

  2015cites this paper
• Methyl rotors in flavoproteins.

  2014cites this paper
• Electron transferases.

  2014cites this paper
• Structural backgrounds for the formation of a catalytically competent complex with NADP(H) during hydride transfer in ferredoxin-NADP(+) reductases.

  2012cites this paper
• Group‐10 Metal Complexes of Biological Molecules and Related Ligands: Structural and Functional Properties

  2012cites this paper
• Understanding the FMN cofactor chemistry within the Anabaena Flavodoxin environment.

  2012cites this paper
• Theoretical study of the mechanism of the hydride transfer between ferredoxin-NADP+ reductase and NADP+: the role of Tyr303.

  2012cites this paper
• Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface.

  2010cites this paper
• Adduct formation between ternary Pt(II)–amino acid–aromatic diimine complexes and flavin mononucleotide and its effect on redox properties

  2009cites this paper
• Flavodoxin: a compromise between efficiency and versatility in the electron transfer from Photosystem I to Ferredoxin-NADP(+) reductase.

  2009cites this paper
• Structural and mechanistic aspects of flavoproteins: photosynthetic electron transfer from photosystem I to NADP+

  2009cites this paper
• Cyanobacterial electron carrier proteins as electron donors to CYP106A2 from Bacillus megaterium ATCC 13368.

  2009cites this paper
• Structural and biochemical characterization of flavoredoxin from the archaeon Methanosarcina acetivorans.

  2008cites this paper
• Docking analysis of transient complexes: Interaction of ferredoxin‐NADP+ reductase with ferredoxin and flavodoxin

  2008cites this paper
• Tuning of the FMN binding and oxido-reduction properties by neighboring side chains in Anabaena flavodoxin.

  2007cites this paper
• Determination of the role of the Carboxyl-terminal leucine-122 in FMN-binding protein by mutational and structural analysis.

  2007cites this paper
• Bioassay-Guided Evolution of Glycosylated Macrolide Antibiotics in Escherichia coli

  2007cites this paper
• ENDOR and related EMR methods applied to flavoprotein radicals

  2007cites this paper
• Review Flavodoxins: sequence, folding, binding, function and beyond

  2006cites this paper
• Dodecins: a family of lumichrome binding proteins.

  2006cites this paper
• Flavodoxins: sequence, folding, binding, function and beyond

  2006cites this paper
• The Function of the Halophilic Dodecin

  2006cites this paper
• Substrate binding modulates the reduction potential of DNA photolyase.

  2005cites this paper
• Electron Transfer in Flavodoxin-based Redox Maquettes

  2005cites this paper
• Anabaena flavodoxin as an electron carrier from photosystem I to ferredoxin-NADP+ reductase. Role of flavodoxin residues in protein-protein interaction and electron transfer.

  2005cites this paper