Decreased GH secretion and enhanced ACTH and cortisol release after ghrelin administration in Cushing’s disease: Comparison with GH-releasing peptide-6 (GHRP-6) and GHRH

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Pituitary

• Publication date

  2006-07-10

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11102-006-9149-8PMID 16832586
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The negative association between total ghrelin levels, body mass and insulin secretion is lost in hypercortisolemic patients with Cushing's disease.

  2005cited by this paper
• Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes.

  2005cited by this paper
• Adrenocorticotropin/Cortisol and Arginine-Vasopressin Secretory Patterns in Response to Ghrelin in Normal Men

  2005cited by this paper
• Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin.

  2004cited by this paper
• Ghrelin--a hormone with multiple functions.

  2004cited by this paper
• Homologous and heterologous regulation of pituitary receptors for ghrelin and growth hormone-releasing hormone.

  2004cited by this paper
• Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.

  2004cited by this paper
• Neuroendocrine and metabolic effects of acute ghrelin administration in human obesity.

  2003cited by this paper
• Ghrelin main action on the regulation of growth hormone release is exerted at hypothalamic level.

  2003cited by this paper
• GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing’s disease: Comparison with DDAVP

  2003cited by this paper
• Ghrelin is Released from Rat Hypothalamic Explants and Stimulates Corticotrophin-releasing Hormone and Arginine-vasopressin*

  2003cited by this paper
• The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.

  2002cited by this paper
• Extent and Direction of Ghrelin Transport Across the Blood-Brain Barrier Is Determined by Its Unique Primary Structure

  2002cited by this paper
• The Hypothalamic Mechanisms of the Hypophysiotropic Action of Ghrelin

  2002cited by this paper
• Ghrelin Is No Longer Able to Stimulate Growth Hormone Secretion in Patients with Cushing’s Syndrome but Instead Induces Exaggerated Corticotropin and Cortisol Responses

  2002influential reference
• Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland

  2001cited by this paper
• The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors.

  2001cited by this paper
• Blockade of the growth hormone (GH) receptor unmasks rapid GH-releasing peptide-6-mediated tissue-specific insulin resistance.

  2001cited by this paper
• Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.

  2001cited by this paper
• Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin

  2001influential reference
• Printed in U.S.A. Copyright © 2001 by The Endocrine Society Genomic Structure and Transcriptional Regulation of the Human Growth Hormone Secretagogue Receptor*

  2000influential reference
• Ghrelin-induced growth hormone secretion in humans.

  2000cited by this paper
• Glucocorticoids Regulate Pituitary Growth Hormone Secretagogue Receptor Gene Expression

  2000cited by this paper
• Ghrelin strongly stimulates growth hormone release in humans.

  2000cited by this paper
• The growth hormone secretagogue hexarelin stimulates the hypothalamo-pituitary-adrenal axis via arginine vasopressin.

  1999cited by this paper
• Ghrelin is a growth-hormone-releasing acylated peptide from stomach

  1999cited by this paper
• Effects of the combined administration of hexarelin, a synthetic peptidyl GH secretagogue, and hCRH on ACTH, cortisol and GH secretion in patients with Cushing’s disease

  1999cited by this paper
• Enhanced growth hormone (GH) responsiveness to GH‐releasing hormone after dietary restriction in patients with Cushing's syndrome

  1998cited by this paper
• Peptidomimetic regulation of growth hormone secretion.

  1997influential reference
• Different effects of growth hormone releasing peptide (GHRP‐6) and GH‐releasing hormone on GH release in endogenous and exogenous hypercortisolism

  1997cited by this paper
• Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH.

  1997cited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Growth Hormone (GH)-Releasing Peptide-6 Requires Endogenous Hypothalamic GH-Releasing Hormone for Maximal GH Stimulation*

  1997cited by this paper
• Signal transduction systems employed by synthetic GH-releasing peptides in somatotrophs.

  1996cited by this paper
• A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

  1996cited by this paper
• Role of glucocorticoids in the neuroregulation of growth hormone secretion.

  1996cited by this paper
• Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level.

  1995cited by this paper
• Inhibition of growth hormone release after the combined administration of CHRH and GHRP‐6 in patients with Cushing's syndrome

  1994cited by this paper
• Growth hormone releasing hormone priming increases growth hormone secretion in patients with Cushing's syndrome

  1993cited by this paper
• Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity.

  1993cited by this paper
• Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors.

  1992cited by this paper
• Pyridostigmine enhances, but does not normalise, the GH response to GH-releasing hormone in obese subjects.

  1990cited by this paper
• Effect of human growth hormone-releasing hormone on GH secretion in Cushing's syndrome and non-endocrine disease patients treated with glucocorticoids.

  1988cited by this paper
• HUMAN PANCREATIC GROWTH HORMONE RELEASING HORMONE FAILS TO STIMULATE HUMAN GROWTH HORMONE BOTH IN CUSHING'S DISEASE AND IN CUSHING'S SYNDROME DUE TO ADRENOCORTICAL ADENOMA

  1986cited by this paper
• On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone.

  1984cited by this paper
• Ulcerative enteritis.

  1983cited by this paper
• The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Endocrine Activities of Ghrelin, a Natural Growth Hormone Secretagogue (GHS), in Humans: Comparison and Interactions with Hexarelin, a Nonnatura

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Expression of the Growth Hormone Secretagogue Receptor in Pituitary Adenomas and Other

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Adrenocorticotropin- and Cortisol-Releasing Effect of Hexarelin, a Synthetic Growth Hormone-Releasing

  year unknowncited by this paper

• Growth Hormone–Releasing Peptides: Investigation of Their Secondary Structure, Thermal Stability, and Model Membrane Interactions

  2026cites this paper
• Ghrelin Represses Thymic Stromal Lymphopoietin Gene Expression through Activation of Glucocorticoid Receptor and Protein Kinase C Delta in Inflamed Skin Keratinocytes

  2022cites this paper
• Ghrelin Actions on Somatotropic and Gonadotropic Function in Humans.

  2016cites this paper
• Combined Administration of Ghrelin and Corticotropin-Releasing Hormone in the Diagnosis of Cushing's Disease

  2016cites this paper
• IMPLICATIONS OF GHRELIN AXIS IN BREAST CANCER--REVIEW.

  2015cites this paper
• Morphology, Localization, and Patterns of Ghrelin-producing Cells in Stomachs of a Morbidly Obese Population

  2014cites this paper
• Structure and Physiological Actions of Ghrelin

  2013cites this paper
• Clinical review: The human experience with ghrelin administration.

  2013cites this paper
• Ghrelin in the hunger : the brain and the pain

  2012cites this paper
• WITHDRAWN: Ghrelin in obesity and endocrine diseases.

  2011cites this paper
• Ghrelin in obesity and endocrine diseases.

  2011cites this paper
• Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing’s disease: comparison with GH‐releasing peptide‐6 (GHRP‐6)

  2010cites this paper
• ACTH and Cortisol responses to ghrelin and desmopressin in patients with Cushing’s disease and adrenal enlargement

  2010cites this paper
• Effects of ghrelin, growth hormone-releasing peptide-6, and growth hormone-releasing hormone on growth hormone, adrenocorticotropic hormone, and cortisol release in type 1 diabetes mellitus.

  2010cites this paper
• ACTH and cortisol responses to ghrelin and desmopressin in patients with Cushing's disease and adrenal enlargement.

  2010cites this paper
• Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH.

  2009cites this paper
• Ghrelin and GHRP-6-induced ACTH and cortisol release in thyrotoxicosis

  2009cites this paper
• Acute ghrelin response to intravenous dexamethasone administration in idiopathic short stature or isolated idiopathic growth hormone-deficient children

  2008cites this paper
• Association between tumoral GH-releasing peptide receptor type 1a mRNA expression and in vivo response to GH-releasing peptide-6 in ACTH-dependent Cushing's syndrome patients.

  2008cites this paper
• Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with Cushing's disease.

  2007cites this paper
• Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin.

  2006cites this paper
• From growth hormone-releasing peptides to ghrelin: discovery of new modulators of GH secretion.

  2006cites this paper