Toxicita hliníka a jeho vplyvy na bunkový cyklus

Abstrakt Hliník sa vo forme zlúčenín bežne vyskytuje v prírode, vo vode, v pôdach aj v potravinách. V neutrálnom pH je takmer nerozpustný, ale v mierne kyslom prostredí sa uvoľňuje vo forme hliníkových iónov Al. Táto forma hliníka môže nepriaznivo vplývať na metabolizmus mikroorganizmov, rastlín aj živočíchov. Expozícia hliníkom je bežnou súčasťou života, ale jeho prestup do krvného obehu je pomerne nízky. Po absorpcii sa však hliník môže dostať do orgánov celého tela. Jeho nadmerná expozícia spôsobuje kumuláciu v rôznych tkanivách, čo má za následok poruchy od bunkového metabolizmu až po rozvoj neurodegeneratívnych ochorení. Príjem hliníka v potrave nemá v ľudskom organizme žiadnu biologicky pozitívnu rolu, a preto je potrebná snaha minimalizovať možnosť expozície touto látkou. Keďže nie sú známe všetky toxické efekty hliníka na základné biologické javy organizmu, ako napríklad bunkový cyklus, na objasnenie ďalších vplyvov hliníka sú preto využívané modelové organizmy.

• Publication year

  2019

• Venue

  Reviewed scientific papers proceeding of the Research Centre AgroBioTech 2019

• Publication date

  2019-10-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.15414/2019.978805520536.p3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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