Calorimetric studies of bovine rod outer segment disk membranes support a monomeric unit for both rhodopsin and opsin.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Biophysical Journal

• Publication date

  2008-09-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1529/biophysj.108.128868PMID 18586850PMCID PMC2527264
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

  2007cited by this paper
• Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets.

  2007influential reference
• Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: Insights from computational analysis

  2007cited by this paper
• G protein-coupled receptors self-assemble in dynamics simulations of model bilayers.

  2007cited by this paper
• Visual Rhodopsin Sees the Light: Structure and Mechanism of G Protein Signaling*

  2007cited by this paper
• Transducin Activation by Nanoscale Lipid Bilayers Containing One and Two Rhodopsins*

  2007cited by this paper
• Proteomic applications of automated GPCR classification

  2007influential reference
• Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes.

  2006cited by this paper
• Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors.

  2006cited by this paper
• G protein-coupled receptor rhodopsin.

  2006cited by this paper
• Identification of pitfalls in the analysis of heat capacity changes of beta-lactoglobulin A.

  2005cited by this paper
• Monomeric G-protein-coupled receptor as a functional unit.

  2005cited by this paper
• Thermotropic behavior of retinal rod membranes and dispersions of extracted phospholipids

  2005cited by this paper
• Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance

  2005cited by this paper
• A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

  2004cited by this paper
• The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes

  2004influential reference
• Roles of G‐protein‐coupled receptor dimerization

  2004cited by this paper
• The Hydrodynamic Properties of Dark- and Light-activated States of n-Dodecyl β-D-Maltoside-solubilized Bovine Rhodopsin Support the Dimeric Structure of Both Conformations*

  2004cited by this paper
• Oligomerization of G protein-coupled receptors: past, present, and future.

  2004cited by this paper
• Functional Characterization of Rhodopsin Monomers and Dimers in Detergents*

  2004cited by this paper
• The Ants Go Marching Two by Two: Oligomeric Structure of G-Protein-Coupled Receptors

  2004cited by this paper
• Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes*

  2003cited by this paper
• Aggregation of bovine insulin probed by DSC/PPC calorimetry and FTIR spectroscopy.

  2003cited by this paper
• Atomic-force microscopy: Rhodopsin dimers in native disc membranes

  2003cited by this paper
• A conformational trigger for activation of a G protein by a G protein-coupled receptor.

  2003cited by this paper
• The wild type bacterial Co(2+)/Co(2+)-phosphotriesterase shows a middle-range thermostability.

  2002cited by this paper
• Signalling: Seven-transmembrane receptors

  2002cited by this paper
• Thermal destabilization of rhodopsin and opsin by proteolytic cleavage in bovine rod outer segment disk membranes.

  2001cited by this paper
• Cholesterol dependent recruitment of di22:6-PC by a G protein-coupled receptor into lateral domains.

  2000cited by this paper
• How photons start vision.

  1996cited by this paper
• Effect of cholesterol on rhodopsin stability in disk membranes.

  1996cited by this paper
• Thermal transitions in the purple membrane from Halobacterium halobium

  1993cited by this paper
• Thermal unfolding and aggregation of human complement protein C9: a differential scanning calorimetry study.

  1991cited by this paper
• Differential scanning calorimetry of bovine rhodopsin in rod-outer-segment disk membranes.

  1991cited by this paper
• Calorimetric study of thermal denaturation of vertebrate visual pigments.

  1988cited by this paper
• Differential scanning calorimetry of the irreversible thermal denaturation of thermolysin.

  1988cited by this paper
• Calorimetric study of thermal denaturation of vertebrate visual pigments.

  1988cited by this paper
• Cross-linking of dark-adapted frog photoreceptor disk membranes. Evidence for monomeric rhodopsin.

  1985cited by this paper
• Effect of alterations in the amphipathic microenvironment on the conformational stability of bovine opsin. 1. Mechanism of solubilization of disk membranes by the nonionic detergent, octyl glucoside.

  1978cited by this paper
• Phase transitions of the purple membranes of Halobacterium halobium.

  1978cited by this paper
• The isolation and purification of osmotically intact discs from retinal rod outer segments.

  1975cited by this paper
• Rhodopsin content in the outer segment membranes of bovine and frog retinal rods.

  1974cited by this paper

• Supramolecular organization of rhodopsin in rod photoreceptor cell membranes

  2021cites this paper
• Cross-linking of bovine rhodopsin with sulfosuccinimidyl 4-(N maleimidomethyl)cyclohexane-1-carboxylate affects its functionality.

  2020cites this paper
• Small-angle neutron and X-ray scattering analysis of the supramolecular organization of rhodopsin in photoreceptor membrane.

  2019cites this paper
• Chapter 15 – Membrane Receptors

  2016cites this paper
• Cholesterol in the rod outer segment: A complex role in a "simple" system.

  2016cites this paper
• Chapter 10 – Membrane Proteins

  2016cites this paper
• Study of visual pigment rhodopsin supramolecular organization in photoreceptor membrane by small-angle neutron scattering method with contrast variation

  2015cites this paper
• Digitonin and sodium dodecylsulfate-solubilized frog rho-dopsin: Behavior under native and denaturing polyacrylamide gel electrophoresis

  2012cites this paper
• Spatial arrangement of rhodopsin in retinal rod outer segment membranes studied by spin-labeling and pulsed electron double resonance.

  2012cites this paper
• The bilayer enhances rhodopsin kinetic stability in bovine rod outer segment disk membranes.

  2011cites this paper
• Recent progress in the study of G protein-coupled receptors with molecular dynamics computer simulations.

  2011cites this paper
• Thermal Denaturation of Membrane Proteins

  2011cites this paper
• Protein kinetic stability.

  2010cites this paper
• Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

  2010cites this paper
• Arrestin-Rhodopsin Binding Stoichiometry in Isolated Rod Outer Segment Membranes Depends on the Percentage of Activated Receptors*♦

  2010cites this paper
• Proof of oligomeric state of frog rhodopsin: Visualization of dimer and oligomers on gels after BN- and HRCN-PAGE using antibodies to rhodopsin and by retinylopsin fluorescence

  2010cites this paper
• Receptor‐Mediated G Protein Activation: How, How Many, and Where?

  2010cites this paper
• Aggregation of frog rhodopsin to oligomers and their dissociation to monomer: Application of BN- and SDS-PAGE

  2009cites this paper
• Activation-dependent Hindrance of Photoreceptor G Protein Diffusion by Lipid Microdomains*

  2008cites this paper