The Cell Cycle: Accelerators, Brakes, and Checkpoints

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Neurosurgery

• Publication date

  2004-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1227/01.NEU.0000109534.28063.5DPMID 15028146
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Primary brain tumours in adults.

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• The anaphase-promoting complex: proteolysis in mitosis and beyond.

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• Cyclin D-dependent kinases, INK4 inhibitors and cancer.

  2002cited by this paper
• Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe

  2002cited by this paper
• p21Cip1 Promotes Cyclin D1 Nuclear Accumulation via Direct Inhibition of Nuclear Export*

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• Overexpression of E2F-1 leads to bax-independent cell death in human glioma cells.

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• Regulation of human separase by securin binding and autocleavage.

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• A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

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• Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

  2001cited by this paper
• Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18Ink4c and p19Ink4d

  2001cited by this paper
• Cell cycle regulation by protein kinases and phosphatases.

  2001cited by this paper
• Genetic epidemiology of glioma

  2001cited by this paper
• Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU.

  2001cited by this paper
• Regulation of the G2/M transition by p53

  2001cited by this paper
• The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27

  2001cited by this paper
• Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex.

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• ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.

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• Delivery of Cell Cycle Genes to Block Astrocytoma Growth

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• High cyclin E/low p27Kip1 expression is associated with poor prognosis in astrocytomas

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• Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas

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• The genetic epidemiology of glioma

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  2000cited by this paper
• Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.

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• APCste9/srw1 promotes degradation of mitotic cyclins in G1 and is inhibited by cdc2 phosphorylation

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• INK4d-Deficient Mice Are Fertile Despite Testicular Atrophy

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• Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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• Cyclin D1 Is Required for Transformation by Activated Neu and Is Induced through an E2F-Dependent Signaling Pathway

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• Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27Kip1 Activity

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• p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin.

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• CDK inhibitors: positive and negative regulators of G1-phase progression.

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• Characterization of a Rac1 Signaling Pathway to Cyclin D1 Expression in Airway Smooth Muscle Cells*

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• Over‐expression of cyclin D1 induces glioma invasion by increasing matrix metalloproteinase activity and cell motility

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• Tumor spectrum in ARF-deficient mice.

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• Regulation of APC Activity by Phosphorylation and Regulatory Factors

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• Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia

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• Amplification and Expression of Cyclin D Genes (CCND1 CCND2 and CCND3) in Human Malignant Gliomas

  1999cited by this paper
• Cyclin D1 expression in astrocytomas is associated with cell proliferation activity and patient prognosis

  1999cited by this paper
• Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2.

  1998cited by this paper
• Requirement of Cyclin E-Cdk2 Inhibition in p16INK4a-Mediated Growth Suppression

  1998cited by this paper
• Overexpression of E2F‐1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

  1998cited by this paper
• A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice.

  1998cited by this paper
• Suppression of human glioma growth by adenovirus-mediated Rb gene transfer

  1998cited by this paper
• Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1).

  1998cited by this paper
• p53-dependent cell cycle control: response to genotoxic stress.

  1998cited by this paper
• Mondor disease: an unusual consideration in a young woman with a breast mass.

  1997cited by this paper
• Cyclin E-CDK2 is a regulator of p27Kip1.

  1997cited by this paper
• Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1

  1997cited by this paper
• Myt1: a Wee1-type kinase that phosphorylates Cdc2 on residue Thr14.

  1997cited by this paper
• Current concepts in neuro-oncology: the cell cycle--a review.

  1997cited by this paper
• Human Myt1 Is a Cell Cycle-regulated Kinase That Inhibits Cdc2 but Not Cdk2 Activity*

  1997cited by this paper
• Cyclin dependent kinase activating kinases.

  1996cited by this paper
• Role of the INK4a locus in tumor suppression and cell mortality.

  1996cited by this paper
• Cyclin D1 Expression Is Regulated Positively by the p42/p44MAPK and Negatively by the p38/HOGMAPK Pathway*

  1996cited by this paper
• Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

  1995cited by this paper
• Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.

  1995cited by this paper
• Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

  1995cited by this paper
• A new type of p16INK4/MTS1 gene transcript expressed in B-cell malignancies.

  1995cited by this paper
• Complex structure and regulation of the P16 (MTS1) locus.

  1995cited by this paper
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  1994cited by this paper
• pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest

  1994cited by this paper
• Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals.

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1989cited by this paper
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  1986cited by this paper
• The ATP-ubiquitin proteolytic pathway.

  1985cited by this paper
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  1983cited by this paper
• Cesium chloride gradients of chromatin after treatment with micrococcal nuclease.

  1976cited by this paper

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