Histologic, serologic, and molecular analysis of persistent ehrlichiosis in a murine model.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  American Journal of Pathology

• Publication date

  2004-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0002-9440(10)63361-5PMID 15331423PMCID PMC1618610
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human ehrlichioses.

  2007cited by this paper
• Overproduction of TNF-α by CD8+ Type 1 Cells and Down-Regulation of IFN-γ Production by CD4+ Th1 Cells Contribute to Toxic Shock-Like Syndrome in an Animal Model of Fatal Monocytotropic Ehrlichiosis1

  2004cited by this paper
• Kinetics of Antibody Response to Ehrlichia canis Immunoreactive Proteins

  2003cited by this paper
• Ehrlichia chaffeensis: a Prototypical Emerging Pathogen

  2003cited by this paper
• Consensus statement on ehrlichial disease of small animals from the infectious disease study group of the ACVIM. American College of Veterinary Internal Medicine.

  2002cited by this paper
• Severe Ehrlichia chaffeensis Infection in a Lung Transplant Recipient: A Review of Ehrlichiosis in the Immunocompromised Patient

  2002cited by this paper
• Persistent Ehrlichia chaffeensis Infection Occurs in the Absence of Functional Major Histocompatibility Complex Class II Genes

  2002cited by this paper
• Immunopathology and ehrlichial propagation are regulated by interferon-gamma and interleukin-10 in a murine model of human granulocytic ehrlichiosis.

  2001cited by this paper
• Reduction in mortality from heartwater in cattle, sheep and goats exposed to field challenge using an inactivated vaccine.

  2001cited by this paper
• Tick-borne infectious diseases of dogs.

  2001cited by this paper
• Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and

  2001cited by this paper
• PERSISTENT EHRLICHIA CHAFFEENSIS INFECTION IN WHITE-TAILED DEER

  2001cited by this paper
• Ehrlichial proliferation and acute hepatocellular necrosis in immunocompetent mice experimentally infected with the HF strain of Ehrlichia, closely related to Ehrlichia chaffeensis.

  2001cited by this paper
• Animal model of fatal human monocytotropic ehrlichiosis.

  2001cited by this paper
• Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in persons coinfected with human immunodeficiency virus.

  2001cited by this paper
• Pathology, immunohistology, and cytokine responses in early phases of human granulocytic ehrlichiosis in a murine model.

  2000cited by this paper
• Comparative pathology, and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections.

  2000cited by this paper
• Molecular Cloning and Characterization of the 120-Kilodalton Protein Gene of Ehrlichia canis and Application of the Recombinant 120-Kilodalton Protein for Serodiagnosis of Canine Ehrlichiosis

  2000cited by this paper
• Severe ehrlichiosis in an adolescent taking trimethoprim-sulfamethoxazole.

  2000cited by this paper
• New Ehrlichia Species Closely Related toEhrlichia chaffeensis Isolated from Ixodes ovatusTicks in Japan

  2000cited by this paper
• Expression of a Gene Encoding the Major Antigenic Protein 2 Homolog of Ehrlichia chaffeensis and Potential Application for Serodiagnosis

  2000cited by this paper
• A POLARIZED TH1 TYPE IMMUNE RESPONSE TO COWDRIA RUMINANTIUM INFECTION IS DETECTED IN IMMUNE DBA/2 MICE

  2000cited by this paper
• A retrospective study of ehrlichiosis in 62 dogs from North Carolina and Virginia.

  1999cited by this paper
• Ehrlichia chaffeensis in Archived Tissues of a White-tailed Deer

  1999cited by this paper
• Comparison of Ehrlichia muris Strains Isolated from Wild Mice and Ticks and Serologic Survey of Humans and Animals with E. muris as Antigen

  1999cited by this paper
• Rapidly fatal infection with Ehrlichia chaffeensis.

  1999cited by this paper
• The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina.

  1999cited by this paper
• Clinical and biological aspects of infection caused by Ehrlichia chaffeensis.

  1999cited by this paper
• Development and distribution of pathologic lesions are related to immune status and tissue deposition of human granulocytic ehrlichiosis agent-infected cells in a murine model system.

  1999cited by this paper
• Infection of the Laboratory Mouse with the Intracellular Pathogen Ehrlichia chaffeensis

  1998cited by this paper
• Sequential Evaluation of Dogs Naturally Infected withEhrlichia canis, Ehrlichia chaffeensis,Ehrlichia equi, Ehrlichia ewingii, orBartonella vinsonii

  1998cited by this paper
• Cloning and sequencing of the gene for a 120-kDa immunodominant protein of Ehrlichia chaffeensis.

  1997cited by this paper
• Human monocytic and granulocytic ehrlichioses. Discovery and diagnosis of emerging tick-borne infections and the critical role of the pathologist.

  1997cited by this paper
• Corrigendum: Cloning and sequencing of the gene for a 120-kDa immunodominant protein of Ehrlichia chaffeensis (Gene (1997) 184 (149-154))

  1997cited by this paper
• Persistent infection of C3H/HeJ mice by Ehrlichia chaffeensis.

  1996cited by this paper
• Impaired Antigen Specific Responses and Enhanced Polyclonal Stimulation in Mice Infected with Ehrlichia muris

  1996cited by this paper
• Ehrlichial Diseases of Humans: Emerging Tick-Borne Infections

  1995cited by this paper
• Ehrlichial diseases of humans: emerging tick-borne infections.

  1995cited by this paper
• Experimental transmission of Ehrlichia chaffeensis (Rickettsiales: Ehrlichieae) among white-tailed deer by Amblyomma americanum (Acari: Ixodidae).

  1995cited by this paper
• Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics.

  1995cited by this paper
• Comparison of PCR with other tests for early diagnosis of canine ehrlichiosis

  1994cited by this paper
• Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis

  1994cited by this paper
• Human ehrlichiosis: hematopathology and immunohistologic detection of Ehrlichia chaffeensis.

  1993cited by this paper
• Persistent infection with Ehrlichia chaffeensis.

  1993cited by this paper
• Characterization of ehrlichial organisms isolated from a wild mouse

  1993influential reference
• Identification of Ehrlichia in human tissue.

  1991cited by this paper
• of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Ehrlichia chaffeensis: a Prototypical Emerging Pathogen Ehrlichia chaffeensis: a Prototypical Emerging Pathogen

  year unknowncited by this paper

• The differences in microbial communities and Tick-Borne pathogens between Dermacentor marginatus and Hyalomma asiaticum collected from the Northwestern Xinjiang Uygur Autonomous Region, China

  2025cites this paper
• Review: Protective Immunity and Immunopathology of Ehrlichiosis.

  2022cites this paper
• Liver Is a Generative Site for the B Cell Response to Ehrlichia muris.

  2019cites this paper
• Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis

  2019cites this paper
• Ehrlichia Isolate from a Minnesota Tick: Characterization and Genetic Transformation

  2019cites this paper
• Pathomorphological and Molecular Detection of Canine Monocytic Ehrlichiosis in a Siberian Husky

  2018cites this paper
• MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock

  2017cites this paper
• Proposal to reclassify Ehrlichia muris as Ehrlichia muris subsp. muris subsp. nov. and description of Ehrlichia muris subsp. eauclairensis subsp. nov., a newly recognized tick-borne pathogen of humans.

  2017cites this paper
• NK Cell-Mediated Regulation of Protective Memory Responses against Intracellular Ehrlichial Pathogens

  2016cites this paper
• Development of Vaccines for Ehrlichiosis

  2016cites this paper
• Co-Feeding Transmission of the Ehrlichia muris–Like Agent to Mice (Mus musculus)

  2016cites this paper
• Ehrlichioses: An Important One Health Opportunity

  2016cites this paper
• Development of Structure-Based Vaccines for Ehrlichiosis.

  2016cites this paper
• Hacker within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming Strategy

  2016cites this paper
• Comorbid Development of Infection and Cancer

  2015cites this paper
• Value of Autopsy Emphasized in the Case Report of a Single Patient with Middle East Respiratory Syndrome

  2015cites this paper
• The role of CD8 T lymphocytes in rickettsial infections

  2015cites this paper
• An animal model of a newly emerging human ehrlichiosis.

  2015cites this paper
• Pathogenesis of Human Ehrlichioses

  2015cites this paper
• Chapter 109 – Ehrlichia

  2015cites this paper
• during Persistent Phagosomal Infection ResponsesFunction , and Secondary Recall T Cell Expansion , + Antigen-Specific CD 4 Early Induction of Interleukin-10 Limits

  2014cites this paper
• Early Induction of Interleukin-10 Limits Antigen-Specific CD4+ T Cell Expansion, Function, and Secondary Recall Responses during Persistent Phagosomal Infection

  2014cites this paper
• Complete Genome Sequence of Ehrlichia muris Strain AS145T, a Model Monocytotropic Ehrlichia Strain

  2014cites this paper
• Neutrophils Mediate Immunopathology and Negatively Regulate Protective Immune Responses during Fatal Bacterial Infection-Induced Toxic Shock

  2013cites this paper
• Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.

  2013cites this paper
• TLR2 and Nod2 Mediate Resistance or Susceptibility to Fatal Intracellular Ehrlichia Infection in Murine Models of Ehrlichiosis

  2013influential citation
• Innate Immune Response and Inflammation: Roles in Pathogenesis and Protection (Anaplasmataceae)

  2012cites this paper
• Transmission Electron Microscopy Reveals Distinct Macrophage- and Tick Cell-Specific Morphological Stages of Ehrlichia chaffeensis

  2012cites this paper
• Immunization with Ehrlichia P28 Outer Membrane Proteins Confers Protection in a Mouse Model of Ehrlichiosis

  2011cites this paper
• The Interaction between IL-18 and IL-18 Receptor Limits the Magnitude of Protective Immunity and Enhances Pathogenic Responses following Infection with Intracellular Bacteria

  2011cites this paper
• Intracellular Bacteria Responses following Infection with Immunity and Enhances Pathogenic Receptor Limits the Magnitude of Protective The Interaction between IL-18 and IL-18

  2011cites this paper
• Structure-Based Vaccines Provide Protection in a Mouse Model of Ehrlichiosis

  2011cites this paper
• Infection-Induced Myelopoiesis during Intracellular Bacterial Infection Is Critically Dependent upon IFN-γ Signaling

  2011influential citation
• Detection of ehrlichial infection by using polymerase chain reaction

  2010cites this paper
• This information is current as Signaling γ Dependent upon IFN-Intracellular Bacterial Infection Is Critically Infection-Induced Myelopoiesis during

  2010influential citation
• MyD88-Dependent Signaling Contributes to Host Defense against Ehrlichial Infection

  2010influential citation
• Antigenic protein modifications in Ehrlichia

  2009cites this paper
• Diminished Hematopoietic Activity Associated with Alterations in Innate and Adaptive Immunity in a Mouse Model of Human Monocytic Ehrlichiosis

  2009cites this paper
• Antigen Display, T-Cell Activation, and Immune Evasion during Acute and Chronic Ehrlichiosis

  2009cites this paper
• Persistent Infection Contributes to Heterologous Protective Immunity against Fatal Ehrlichiosis

  2009cites this paper
• Autoimmune disease triggered by infection with alphaproteobacteria

  2009cites this paper
• Intracellular Bacterial Infection T-Independent Antibody Responses during Plasmablasts Responsible for CD 4 Extrafollicular Antigen-Specific Splenic CD 11 c Expression Identifies a Population of Winslow

  2008cites this paper
• Regulatory Roles of CD1d-Restricted NKT Cells in the Induction of Toxic Shock-Like Syndrome in an Animal Model of Fatal Ehrlichiosis

  2008cites this paper
• Molecular evaluation of Ehrlichia chaffeensis

  2008cites this paper
• Protective Heterologous Immunity against Fatal Ehrlichiosis and Lack of Protection following Homologous Challenge

  2008cites this paper
• Defining the immune response to Ehrlichia species using murine models.

  2008influential citation
• CD11c Expression Identifies a Population of Extrafollicular Antigen-Specific Splenic Plasmablasts Responsible for CD4 T-Independent Antibody Responses during Intracellular Bacterial Infection1

  2008cites this paper
• T-Cell-Independent Humoral Immunity Is Sufficient for Protection against Fatal Intracellular Ehrlichia Infection

  2007influential citation
• Detection and Identification of Bacterial Agents in Ixodes persulcatus Schulze Ticks from the North Western Region of Russia

  2007cites this paper
• Relative Importance of T-Cell Subsets in Monocytotropic Ehrlichiosis: a Novel Effector Mechanism Involved in Ehrlichia-Induced Immunopathology in Murine Ehrlichiosis

  2007cites this paper
• CD4 T-Cell Epitopes Associated with Protective Immunity Induced following Vaccination of Mice with an Ehrlichial Variable Outer Membrane Protein

  2007cites this paper
• Virulence Potential of Ehrlichia chaffeensis Strains of Distinct Genome Sequences

  2007cites this paper
• Human ehrlichioses.

  2007cites this paper
• An Intradermal Environment Promotes a Protective Type-1 Response against Lethal Systemic Monocytotropic Ehrlichial Infection

  2006cites this paper
• Role of Tumor Necrosis Factor Alpha (TNF-α) and Interleukin-10 in the Pathogenesis of Severe Murine Monocytotropic Ehrlichiosis: Increased Resistance of TNF Receptor p55- and p75-Deficient Mice to Fatal Ehrlichial Infection

  2006cites this paper
• Fatal Recall Responses Mediated by CD8 T cells during Intracellular Bacterial Challenge Infection1

  2006cites this paper
• This information is current as Infection cells during Intracellular Bacterial Challenge Fatal Recall Responses Mediated by CD 8 T

  2006cites this paper
• Role of reactive nitrogen species in development of hepatic injury in a C57bl/6 mouse model of human granulocytic anaplasmosis.

  2006cites this paper
• Analysis of Ehrlichial p28 Gene Expression in a Murine Model of Persistent Infection

  2005cites this paper
• Nitric Oxide as a Mediator of Increased Microvascular Permeability during Acute Rickettsioses

  2005cites this paper
• Ehrlichia under our noses and no one notices.

  2005cites this paper
• Immunity to the ehrlichiae: new tools and recent developments

  2005cites this paper