Vaporization, bioactive formulations and a marine natural product: different perspectives on antivirals

T. Manning,Jenu Thomas-Richardson,M. Cowan,Torien Beard

Published 2020 in Drug Discovery Today

ABSTRACT

Graphical Abstract This note examines three aspects of antivirals as they can potentially relate to the treatment of COVID-19; (i) the use of vaporization for the delivery of antivirals, with the bulk constituents having mild antiviral efficacy, (ii) a counter intuitive approach to formulation that, is in part, based on delivering multiple species that fall into three categories; building blocks for the virus to accelerate replication; an energy source for the infected cell to boast its immune response; species that antagonize or provide toxicity to the virus, (iii) the application of a marine natural product extract with several species, as opposed to a focusing on a single molecule as the anti-viral agent.

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REFERENCES

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