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Mortality from necrotizing fasciitis: a cross-sectional study

P. Paul,I. Prabhakaran,M. Chisthi

Published 2020 in International Surgery Journal

ABSTRACT

Necrotizing fasciitis (NF) is a rapidly progressive inflammatory infection of the fascia, with secondary necrosis of the subcutaneous tissues. The term ‘Necrotizing fasciitis’ was first described in 1952 by Wilson. The speed of spread is directly proportional to the thickness of the subcutaneous layer, wherein the infection moves along the fascial planes. It is a surgical emergency which needs to be diagnosed timely and treated with early debridement. Delayed intervention could result in extremely high mortality rate (~80 to 100%), and even with modern aggressive treatment modalities, mortality remains high, approaching as high as 36-40%. Of late, the incidence of NF is seen to be on the rise because of an increase in immunocompromised patients like those with diabetes mellitus, cancers, vascular insufficiencies, organ transplants and HIV infection.

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