Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Journal of Immunology

• Publication date

  2018-05-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1701406PMID 29760191PMCID PMC6008236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes

  2017cited by this paper
• Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

  2017cited by this paper
• Galectins expressed differently in genetically susceptible C57BL/6 and resistant BALB/c mice during acute ocular Toxoplasma gondii infection

  2017cited by this paper
• IFN-γ increases susceptibility to influenza A infection through suppression of group II innate lymphoid cells

  2017cited by this paper
• Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells

  2017cited by this paper
• Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

  2017cited by this paper
• A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

  2016cited by this paper
• Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease

  2015cited by this paper
• CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs

  2015cited by this paper
• The immunology of influenza virus-associated bacterial pneumonia.

  2015cited by this paper
• Delivery of GM-CSF to Protect against Influenza Pneumonia

  2015cited by this paper
• Alveolar macrophages support interferon gamma-mediated viral clearance in RSV-infected neonatal mice

  2015cited by this paper
• Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice.

  2015cited by this paper
• Differences in the Pathogenicity and Inflammatory Responses Induced by Avian Influenza A/H7N9 Virus Infection in BALB/c and C57BL/6 Mouse Models

  2014cited by this paper
• Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

  2014cited by this paper
• The co-pathogenesis of influenza viruses with bacteria in the lung

  2014cited by this paper
• Fas ligand-expressing lymphocytes enhance alveolar macrophage apoptosis in the resolution of acute pulmonary inflammation.

  2014cited by this paper
• Influenza Infection Suppresses NADPH Oxidase–Dependent Phagocytic Bacterial Clearance and Enhances Susceptibility to Secondary Methicillin-Resistant Staphylococcus aureus Infection

  2014cited by this paper
• Immune Dysfunction and Bacterial Coinfections following Influenza

  2013cited by this paper
• Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung.

  2013influential reference
• Linezolid Decreases Susceptibility to Secondary Bacterial Pneumonia Postinfluenza Infection in Mice Through its Effects on IFN-γ

  2013cited by this paper
• Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

  2013influential reference
• Bacterial Complications of Respiratory Tract Viral Illness: A Comprehensive Evaluation

  2013cited by this paper
• Gamma Interferon Regulates Contraction of the Influenza Virus-Specific CD8 T Cell Response and Limits the Size of the Memory Population

  2013cited by this paper
• Identification of myeloid cell subsets in murine lungs using flow cytometry.

  2013influential reference
• Immunological Variation Between Inbred Laboratory Mouse Strains

  2012cited by this paper
• This information is current as Inflammatory Lung Disease Characterize Acute Infection and Chronic Distinct Macrophage Subpopulations

  2012cited by this paper
• Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury.

  2011influential reference
• Differential effect of prior influenza infection on alveolar macrophage phagocytosis of Staphylococcus aureus and Escherichia coli: involvement of interferon‐gamma production

  2011cited by this paper
• GM-CSF in the lung protects against lethal influenza infection.

  2011cited by this paper
• Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.

  2011cited by this paper
• Interferon Gamma Activated Macrophages Kill Mycobacteria by Nitric Oxide Induced Apoptosis

  2011cited by this paper
• Seasonal FluMist Vaccination Induces Cross-Reactive T Cell Immunity against H1N1 (2009) Influenza and Secondary Bacterial Infections

  2011cited by this paper
• Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

  2011cited by this paper
• Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections.

  2010cited by this paper
• Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production

  2009cited by this paper
• Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections

  2009cited by this paper
• Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness.

  2008cited by this paper
• Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

  2008cited by this paper
• Pandemic and seasonal influenza: therapeutic challenges.

  2008cited by this paper
• CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality1

  2008cited by this paper
• A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

  2008cited by this paper
• The prolonged life-span of alveolar macrophages.

  2008cited by this paper
• Lung Macrophages Serve as Obligatory Intermediate between Blood Monocytes and Alveolar Macrophages1

  2007cited by this paper
• Influenza A Virus PB1-F2 Protein Contributes to Viral Pathogenesis in Mice

  2006cited by this paper
• MARCO Mediates Silica Uptake and Toxicity in Alveolar Macrophages from C57BL/6 Mice*

  2006cited by this paper
• Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation.

  2006cited by this paper
• Differential expression of IL‐10 receptor by epithelial cells and alveolar macrophages

  2004cited by this paper
• Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection 1

  2003cited by this paper
• Mechanisms of Enhanced Macrophage-Mediated Prostaglandin E2 Production and Its Suppressive Role in Th1 Activation in Th2-Dominant BALB/c Mice1

  2003cited by this paper
• The immunology of susceptibility and resistance to Leishmania major in mice

  2002cited by this paper
• Reduced Expression of STAT4 and IFN-γ in Macrophages from BALB/c Mice1

  2002cited by this paper
• Reduced expression of STAT4 and IFN-gamma in macrophages from BALB/c mice.

  2002cited by this paper
• A novel influenza A virus mitochondrial protein that induces cell death

  2001cited by this paper
• Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology.

  2001cited by this paper
• The Role of Alpha/Beta and Gamma Interferons in Development of Immunity to Influenza A Virus in Mice

  2000cited by this paper
• Genealogies of mouse inbred strains

  2000cited by this paper
• Macrophage Cholesterol Metabolism, Apolipoprotein E, and Scavenger Receptor AI/II mRNA in Atherosclerosis-Susceptible and -Resistant Mice

  2000cited by this paper
• M-1/M-2 Macrophages and the Th1/Th2 Paradigm1

  2000cited by this paper
• Gamma Interferon Modulates CD95 (Fas) and CD95 Ligand (Fas-L) Expression and Nitric Oxide-Induced Apoptosis during the Acute Phase ofTrypanosoma cruzi Infection: a Possible Role in Immune Response Control

  1999cited by this paper
• The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

  1999cited by this paper
• Alveolar macrophage apoptosis and TNF-α, but not p53, expression correlate with murine response to bleomycin.

  1998cited by this paper
• Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-gamma production.

  1998cited by this paper
• Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: an essential role for gamma interferon

  1994cited by this paper
• Pulmonary antibacterial defenses during mild and severe influenza virus infection

  1990cited by this paper
• Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

  1989cited by this paper
• Effect of influenza viral infection on the ingestion and killing of bacteria by alveolar macrophages.

  1977cited by this paper
• Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza.

  1959cited by this paper

• Respiratory Viral and Bacterial Superinfection

  2026cites this paper
• Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia.

  2026cites this paper
• Transient lung eosinophilia during breakthrough influenza infection in vaccinated mice is associated with protective and balanced Type 1/2 immune responses

  2025cites this paper
• Influenza infection exacerbates high-fat diet-induced atherosclerosis in apolipoprotein gene-deficient mice.

  2025cites this paper
• Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice

  2025cites this paper
• Omadacycline exhibits anti-inflammatory properties and improves survival in a murine model of post-influenza MRSA pneumonia

  2025cites this paper
• Emerging highly pathogenic H5N1 influenza triggers fibrotic remodeling in human airway organoids

  2025cites this paper
• Swine influenza A virus infection sets the local immunological landscape in subsequent infection with porcine reproductive and respiratory syndrome virus

  2025cites this paper
• Transient lung eosinophilia during breakthrough influenza infection in vaccinated mice is associated with protective and balanced Type 1/2 immune responses

  2025cites this paper
• Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes.

  2025cites this paper
• Type I Interferon Targets Alveolar Macrophages to Promote Bacterial Pneumonia after Viral Infection.

  2025cites this paper
• Evaluating the evidence for GM-CSF as a host-directed therapy in respiratory infections.

  2025cites this paper
• Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice

  2025cites this paper
• Journey of monocytes and macrophages upon influenza A virus infection.

  2024cites this paper
• Metformin improves Mycobacterium avium infection by strengthening macrophage antimicrobial functions

  2024cites this paper
• Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma

  2024cites this paper
• The deadly dance of alveolar macrophages and influenza virus

  2024cites this paper
• Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

  2024cites this paper
• The role of alveolar macrophages in viral respiratory infections and their therapeutic implications

  2024cites this paper
• Predictive signature of murine and human host response to typical and atypical pneumonia

  2024cites this paper
• TNF superfamily member 14 drives post-influenza depletion of alveolar macrophages, enabling secondary pneumococcal pneumonia

  2024cites this paper
• Transcriptional and functional remodeling of lung-resident T cells and macrophages by Simian varicella virus infection

  2024cites this paper
• In Vivo Immune-Modulatory Activity of Lefamulin in an Influenza Virus A (H1N1) Infection Model in Mice

  2024cites this paper
• A Functional Assessment of Fetal Liver and Monocyte-Derived Macrophages in the Lung Alveolar Environment.

  2024cites this paper
• Multicompartmental analysis of the murine pulmonary immune response by spectral flow cytometry

  2023cites this paper
• Interaction among inflammasome, PANoptosise, and innate immune cells in infection of influenza virus: Updated review

  2023cites this paper
• Immune predisposition drives susceptibility to pneumococcal pneumonia after mild influenza A virus infection in mice

  2023cites this paper
• Respiratory viral infections in the elderly: From the perspective of the aging immune system

  2023cites this paper
• Reply to: The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function

  2023cites this paper
• Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs

  2023cites this paper
• How aging impacts vaccine efficacy: known molecular and cellular mechanisms and future directions.

  2022cites this paper
• Gammaherpesvirus Alters Alveolar Macrophages According to the Host Genetic Background and Promotes Beneficial Inflammatory Control over Pneumovirus Infection

  2022cites this paper
• Viral PB1-F2 and host IFN-γ guide ILC2 and T cell activity during influenza virus infection

  2022cites this paper
• Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infection during SARS-CoV-2 Infection

  2022cites this paper
• Pulmonary macrophages and SARS-Cov2 infection

  2022cites this paper
• Mechanistic Basis of Super-Infection: Influenza-Associated Invasive Pulmonary Aspergillosis

  2022cites this paper
• Lethal synergy between SARS-CoV-2 and Streptococcus pneumoniae in hACE2 mice and protective efficacy of vaccination.

  2022cites this paper
• Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infections During SARS-CoV-2

  2022cites this paper
• The role of Fibroblast Growth Factor-9 in influenza A virus pathogenesis

  2022cites this paper
• Type I IFN Signaling Is Essential for Preventing IFN-γ Hyperproduction and Subsequent Deterioration of Antibacterial Immunity during Postinfluenza Pneumococcal Infection

  2022cites this paper
• Cysteinyl Maresins Reprogram Macrophages to Protect Mice from Streptococcus pneumoniae after Influenza A Virus Infection

  2022cites this paper
• Intranasal delivery of NS1-deleted influenza virus vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response

  2022cites this paper
• Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis

  2022cites this paper
• Disease Tolerance during Viral-Bacterial Co-Infections

  2021cites this paper
• Effect of Vitamin A Deficiency in Dysregulating Immune Responses to Influenza Virus and Increasing Mortality Rates After Bacterial Coinfections

  2021cites this paper
• Pathogenesis of Respiratory Viral and Fungal Coinfections

  2021cites this paper
• A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells

  2021cites this paper
• Aging Regulates Post-Viral Asthmatic Airway Pathology

  2021cites this paper
• Monocytes and Macrophages in COVID-19

  2021cites this paper
• Altered Signal Transduction in the Immune Response to Influenza Virus and S. pneumoniae or S. aureus Co-Infections

  2021cites this paper
• Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza

  2021cites this paper
• Enhanced Pathogenesis Caused by Influenza D Virus and Mycoplasma bovis Coinfection in Calves: a Disease Severity Linked with Overexpression of IFN-γ as a Key Player of the Enhanced Innate Immune Response in Lungs

  2021cites this paper
• Too young to die? How aging affects cellular innate immune responses to influenza virus and disease severity

  2021influential citation
• Distinctive features of severe SARS-CoV-2 pneumonia.

  2021cites this paper
• TIGIT limits immune pathology during viral infections

  2020cites this paper
• Innate immune memory of tissue‐resident macrophages and trained innate immunity: Re‐vamping vaccine concept and strategies

  2020cites this paper
• Recognizing limits of Z‐nucleic acid binding protein (ZBP1/DAI/DLM1) function

  2020cites this paper
• State-of-the-art in the pneumococcal field: Proceedings of the 11th International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD-11)

  2020cites this paper
• Inflammation as a Modulator of Host Susceptibility to Pulmonary Influenza, Pneumococcal, and Co-Infections

  2020cites this paper
• Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia

  2020cites this paper
• Double hit viral parasitism, polymicrobial CNS residency and perturbed proteostasis in Alzheimer's disease: A data driven, in silico analysis of gene expression data.

  2020cites this paper
• Vitamin A deficiency dysregulates immune responses toward influenza virus and increases mortality after bacterial coinfections.

  2020cites this paper
• Influenza Infection Induces Alveolar Macrophage Dysfunction and Thereby Enables Noninvasive Streptococcus pneumoniae to Cause Deadly Pneumonia

  2020cites this paper
• Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis.

  2020cites this paper
• Influenza sequelae: from immune modulation to persistent alveolitis.

  2020cites this paper
• Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell responses

  2020cites this paper
• Influenza Suppresses Neutrophil Recruitment to the Lung and Exacerbates Secondary Invasive Pulmonary Aspergillosis

  2020cites this paper
• Non-sterilizing, Infection-Permissive Vaccination With Inactivated Influenza Virus Vaccine Reshapes Subsequent Virus Infection-Induced Protective Heterosubtypic Immunity From Cellular to Humoral Cross-Reactive Immune Responses

  2020cites this paper
• Diverse and Unexpected Roles of Human Monocytes/Macrophages in the Immune Response to Influenza Virus

  2020cites this paper
• Allergic Airway Disease Prevents Lethal Synergy of Influenza A Virus-Streptococcus pneumoniae Coinfection

  2019cites this paper
• Monocytes Represent One Source of Bacterial Shielding from Antibiotics following Influenza Virus Infection

  2019cites this paper
• Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae

  2019cites this paper
• RETRACTED: Contribution of Host Immune Responses against Influenza D Virus Infection toward Secondary Bacterial Infection in a Mouse Model

  2019cites this paper
• TIV Vaccination Modulates Host Responses to Influenza Virus Infection that Correlate with Protection against Bacterial Superinfection

  2019cites this paper
• Screening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A

  2019cites this paper
• In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection

  2019influential citation
• Dynamic Pneumococcal Genetic Adaptations Support Bacterial Growth and Inflammation during Coinfection with Influenza

  2019cites this paper
• Validated Models of Immune Response to Virus Infection.

  2018cites this paper
• Impact d’une infection par le virus grippal de type A sur la myélopoïèse

  2018cites this paper
• Hormonal Regulation of Physiology, Innate Immunity and Antibody Response to H1N1 Influenza Virus Infection During Pregnancy

  2018cites this paper
• Host‐pathogen kinetics during influenza infection and coinfection: insights from predictive modeling

  2018cites this paper
• Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

  2018cites this paper
• Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia

  2018cites this paper