Ursodeoxycholic acid reduces protein levels and nucleation-promoting activity in human gallbladder bile.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Gastroenterology

• Publication date

  1996-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1053/GAST.1996.V110.PM8613013PMID 8613013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biliary haptoglobin, a potent promoter of cholesterol crystallization at physiological concentrations.

  1995cited by this paper
• Effect of deoxycholate on immunoglobulin G concentration in bile: Studies in humans and pigs

  1995cited by this paper
• Quantification of mucin in human gallbladder bile: a fast, specific, and reproducible method.

  1995cited by this paper
• Model bile and bile salts accelerate mucin secretion by cultured dog gallbladder epithelial cells.

  1995cited by this paper
• Phospholipid molecular species influence crystal habits and transition sequences of metastable intermediates during cholesterol crystallization from bile salt-rich model bile.

  1994cited by this paper
• Increased biliary protein precedes gallstone formation

  1994cited by this paper
• Identification of a 130-kilodalton human biliary concanavalin A binding protein as aminopeptidase N.

  1994cited by this paper
• Heterogeneity of human gallbladder mucin in bile.

  1994cited by this paper
• The complete mapping of cholesterol crystal nucleation paths in model and native bile

  1994cited by this paper
• Effect of human biliary immunoglobulins on the nucleation of cholesterol.

  1993cited by this paper
• Molecular composition of biliary phosphatidylcholines, as related to cholesterol saturation, transport and nucleation in human gallbladder bile.

  1992cited by this paper
• Effect of chenodeoxycholate and ursodeoxycholate on nucleation time in human gallbladder bile.

  1992cited by this paper
• Diurnal variation in cholesterol metastability of hepatic bile and its acute modulation with ursodeoxycholic acid in humans.

  1992cited by this paper
• Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones

  1992cited by this paper
• Aspirin does not inhibit cholesterol cholelithiasis in two established animal models.

  1991cited by this paper
• Role of high total protein in gallbladder bile in the formation of cholesterol gallstones.

  1991cited by this paper
• Immunoglobulins as nucleating proteins in the gallbladder bile of patients with cholesterol gallstones.

  1991cited by this paper
• Inhibition of prostaglandin synthesis fails to prevent gallbladder mucin hypersecretion in the cholesterol-fed prairie dog.

  1991cited by this paper
• Nucleation of cholesterol crystals from native bile and the effect of protein hydrolysis.

  1991cited by this paper
• Distribution of cholesterol between vesicles and micelles in human gallbladder bile: Influence of treatment with chenodeoxycholic acid and ursodeoxycholic acid

  1991cited by this paper
• The effect of ursodiol on the efficacy and safety of extracorporeal shock-wave lithotripsy of gallstones. The Dornier National Biliary Lithotripsy Study.

  1990cited by this paper
• High protein and total lipid concentration are associated with reduced metastability of bile in an early stage of cholesterol gallstone formation.

  1990cited by this paper
• Isolation of a potent cholesterol nucleation‐promoting activity from human gallbladder bile: Role in the pathogenesis of gallstone disease

  1990cited by this paper
• Bile concentration is a key factor for nucleation of cholesterol crystals and cholesterol saturation index in gallbladder bile of gallstone patients

  1990cited by this paper
• Gallbladder motility in cholesterol gallstone disease. Effect of ursodeoxycholic acid administration and gallstone dissolution.

  1990cited by this paper
• Effects of ursodeoxycholic acid on gallbladder contraction and cholecystokinin release in gallstone patients and normal subjects.

  1990cited by this paper
• A sensitive method for determination of cholesterol growth using model solutions of supersaturated bile.

  1990cited by this paper
• Gallstone recurrence after successful oral bile acid treatment. A 12-year follow-up study and evaluation of long-term postdissolution treatment.

  1989cited by this paper
• Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions.

  1989cited by this paper
• Prevention of gallstone recurrence by non-steroidal anti-inflammatory drugs.

  1988cited by this paper
• Cholesterol and pigment gallstone disease: comparison of the reliability of three bile tests for differentiation between the two stone types.

  1988cited by this paper
• Whither biliary sludge?

  1988cited by this paper
• Gallbladder function during gallstone dissolution. Effect of bile acid therapy in patients with gallstones.

  1988cited by this paper
• Mucin in gall bladder bile of gall stone patients: influence of treatment with chenodeoxycholic acid and ursodeoxycholic acid.

  1988cited by this paper
• Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight.

  1988cited by this paper
• Cholesterol nucleation‐influencing activity in t‐tube bile

  1988cited by this paper
• Biliary proteins and the nucleation defect in cholesterol cholelithiasis.

  1987cited by this paper
• Fluorometric assay of O-linked glycoproteins by reaction with 2-cyanoacetamide.

  1987cited by this paper
• Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-nor-ursodeoxycholate in rodents.

  1986cited by this paper
• Effect of ursodeoxycholic acid and chenodeoxycholic acid on cholesterol and bile acid metabolism.

  1986cited by this paper
• A sensitive method for quantitative analysis of phospholipid molecular species by high-performance liquid chromatography.

  1985cited by this paper
• Factors affecting cholesterol monohydrate crystal nucleation time in model systems of supersaturated bile.

  1985cited by this paper
• Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat.

  1985cited by this paper
• Biliary proteins. Unique inhibitors of cholesterol crystal nucleation in human gallbladder bile.

  1984cited by this paper
• Effect of taurochenodeoxycholate or tauroursodeoxycholate upon biliary output of phospholipids and plasma-membrane enzymes, and the extent of cell damage, in isolated perfused rat livers.

  1983cited by this paper
• Cholesterol gallstone dissolution in bile. Dissolution kinetics of crystalline cholesterol monohydrate by conjugated chenodeoxycholate-lecithin and conjugated ursodeoxycholate-lecithin mixtures: dissimilar phase equilibria and dissolution mechanisms.

  1983cited by this paper
• Aspirin prevention of cholesterol gallstone formation in prairie dogs.

  1981cited by this paper
• Structure of biliary phosphatidylcholine in cholesterol gallstone patients

  1981cited by this paper
• Use of a simple enzymatic assay for cholesterol analysis in human bile.

  1980cited by this paper
• Effects of bile salts on the plasma membranes of isolated rat hepatocytes.

  1980cited by this paper
• Coordinate secretion of acid hydrolases in rat bile.

  1979cited by this paper
• Critical tables for calculating the cholesterol saturation of native bile.

  1978cited by this paper
• Pigment vs cholesterol cholelithiasis: Comparison of stone and bile composition

  1974cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• THIN-LAYER CHROMATOGRAPHY OF PHOSPHOLIPIDS USING SILICA GEL WITHOUT CALCIUM SULFATE BINDER.

  1963cited by this paper
• A rapid method of total lipid extraction and purification.

  1959cited by this paper

• Effect of cholesterol metabolism on hepatolithiasis

  2025cites this paper
• Bile acid preparation and comprehensive analysis by high performance liquid chromatography-high-resolution mass spectrometry.

  2017cites this paper
• Pro‐oxidants or anti‐oxidant defenses? Which one to blame in non‐alcoholic steatohepatitis pathogenesis?

  2012cites this paper
• Bile Salts and Nuclear Receptors in Biliary Epithelial Cell Pathophysiology

  2012cites this paper
• Effect of Ursodeoxycholic Acid Administration after Liver Transplantation on Serum Liver Tests and Biliary Complications: A Randomized Clinical Trial

  2012cites this paper
• N‐3 polyunsaturated fatty acid attenuates cholesterol gallstones by suppressing mucin production with a high cholesterol diet in mice

  2012cites this paper
• Can fish oil dissolve gallstones?

  2012cites this paper
• Pathogenesis of gallstones.

  2010cites this paper
• Biliary proteins and their redox status changes in gallstone patients

  2009cites this paper
• Effects of Aramchol on in vitro bile cholesterol crystallization and bile acid detergency

  2008cites this paper
• Ursodeoxycholic acid: Mechanism of action and novel clinical applications

  2007cites this paper
• Ursodeoxycholic acid exerts no beneficial effect in patients with symptomatic gallstones awaiting cholecystectomy

  2006cites this paper
• Primary sclerosing cholangitis: updates in diagnosis and therapy.

  2005cites this paper
• Small gallstones, preserved gallbladder motility, and fast crystallization are associated with pancreatitis

  2005cites this paper
• Cholesterol saturation rather than phospholipid/bile salt ratio or protein content affects crystallization sequences in human gallbladder bile

  2004cites this paper
• Ursodeoxycholic acid decreases viscosity and sedimentable fractions of gallbladder bile in patients with cholesterol gallstones

  2004cites this paper
• Effects of Ursodeoxycholic Acid Therapy on In Vitro Gallbladder Contractility in Patients with Cholesterol Gallstones

  2004cites this paper
• Prevention of gallstones by ursodeoxycholic acid after cardiac surgery

  2003cites this paper
• Hepatolithiasis--epidemiology and pathogenesis update.

  2003cites this paper
• Pathways of cholesterol crystallization in model bile and native bile.

  2003cites this paper
• Biliary pronucleating proteins and apolipoprotein E in cholesterol and pigment stone patients.

  2003cites this paper
• Prevention of black pigment gallstone formation after cardiac surgery by ursodeoxycholic acid

  2003cites this paper
• Microlithiasis: an important cause of "idiopathic" acute pancreatitis?

  2003cites this paper
• Quantitation of cholesterol crystallization from supersaturated model bile.

  2002cites this paper
• Hepatic apolipoprotein A-I gene expression in patients with cholesterol gallstones treated with ursodeoxycholic acid.

  2002cites this paper
• Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles.

  2002cites this paper
• From lipid secretion to cholesterol crystallization in bile. Relevance in cholesterol gallstone disease.

  2002cites this paper
• Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo.

  2001cites this paper
• Bile acid transport and regulating functions in the human biliary epithelium

  2001cites this paper
• Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles.

  2001cites this paper
• Cholesterol crystallization in model biles: effects of bile salt and phospholipid species composition.

  2001cites this paper
• Gallbladder motility and cholesterol crystallization in bile from patients with pigment and cholesterol gallstones

  2000cites this paper
• Iatrogenic occlusion of biliary endoprostheses by ursodeoxycholic acid.

  1999cites this paper
• Deoxycholic acid is not related to lithogenic factors in gallbladder bile.

  1999cites this paper
• Electrophoretic analysis of proteins in bile

  1999cites this paper
• Effects of long‐term ursodeoxycholate administration on expression levels of secretory low–molecular‐weight phospholipases A and mucin genes in gallbladders and biliary composition in patients with multiple cholesterol stones

  1998cites this paper
• EFFECTIVENESS OF COMBINATION THERAPY OF ENDOSCOPIC BILIIARY DRAINAGE AND URSODEOXYCHOLIC ACID FOR AN ELIDER PATIENT WITH BILIOENTE:LIC ANASTOMOTIC STRICTURE AND BILEDUCT STONES

  1998cites this paper
• An update on the pathogenesis and treatment of cholesterol gallstones.

  1997cites this paper
• Cholesterol crystallisation in bile

  1997cites this paper
• [Role of biliary proteins in pathogenesis of cholesterol gallstones].

  1997cites this paper
• Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile

  1996cites this paper
• Bile Salts and Nuclear Receptors in Biliary Epithelial Cell Pathophysiology

  year unknowncites this paper