Plant and animal chromatin 3D organization, similar structure but different function.

Chromatin is the main carrier of genetic information and non-randomly distributed within the nucleus. Next generation sequence-based chromatin conformation capture technologies have enabled us to directly examine its 3D organization at an unprecedented scale and resolution. In the best studied mammalian models, chromatin folding can be broken down into three hierarchical levels, compartment, domains, and loops, which play important roles in transcriptional regulation. Although similar structures have now been identified in plants, they might not process identical function as the mammalian ones. Here, we review the recent plant Hi-C and ChIA-PET findings, compare plant chromatin structures with their mammalian counterparts, and also discuss the differences between plants of different genome sizes.

• Publication year

  2020

• Venue

  Journal of Experimental Botany

• Publication date

  2020-05-06

• Fields of study

  Biology, Medicine, Materials Science, Environmental Science

• Identifiers
  DOI 10.1093/jxb/eraa220PMID 32374833
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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