SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2015-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.bbrc.2015.03.012PMID 25770425
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PCDH10 is required for the tumorigenicity of glioblastoma cells.

  2014cited by this paper
• The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis

  2014cited by this paper
• The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells

  2014cited by this paper
• Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo

  2013cited by this paper
• LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

  2013cited by this paper
• The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration

  2013cited by this paper
• Oncogenic role of SOX9 expression in human malignant glioma

  2012cited by this paper
• Slug and Sox9 cooperatively determine the mammary stem cell state.

  2012cited by this paper
• LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling

  2011cited by this paper
• Sox9 function in craniofacial development and disease

  2011cited by this paper
• R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling

  2011cited by this paper
• Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

  2011cited by this paper
• Tumorigenesis and Neoplastic Progression G-Protein-Coupled Receptor GPR 49 is Up-regulated in Basal Cell Carcinoma and Promotes Cell Proliferation and Tumor Formation

  2010cited by this paper
• Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells.

  2010cited by this paper
• Identification of SOX9 Interaction Sites in the Genome of Chondrocytes

  2010cited by this paper
• Lgr5 marks cycling, yet long-lived, hair follicle stem cells

  2008cited by this paper
• Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

  2007cited by this paper
• GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model

  2007cited by this paper
• Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

  2006cited by this paper
• Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.

  1998cited by this paper

• Potent synthetic lethality between PLK1 and EYA family inhibitors in tumors of the central and peripheral nervous systems

  2025cites this paper
• SOX9 modulates the transformation of gastric stem cells through biased symmetric cell division.

  2023cites this paper
• Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival

  2022cites this paper
• Stat5b inhibition blocks proliferation and tumorigenicity of glioblastoma stem cells derived from a de novo murine brain cancer model.

  2022cites this paper
• miR-30c plays diagnostic and prognostic roles and mediates epithelial–mesenchymal transition (EMT) and proliferation of gliomas by affecting Notch1

  2021cites this paper
• ZRANB1 enhances stem-cell-like features and accelerates tumor progression by regulating Sox9-mediated USP22/Wnt/β-catenin pathway in colorectal cancer.

  2021cites this paper
• OSR1 suppresses acute myeloid leukaemia cell proliferation by inhibiting LGR5-mediated JNK signalling

  2021cites this paper
• Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp.

  2020cites this paper
• The role of SOX family members in solid tumours and metastasis.

  2020cites this paper
• SOX9‐activated PXN‐AS1 promotes the tumorigenesis of glioblastoma by EZH2‐mediated methylation of DKK1

  2020cites this paper
• Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp

  2020cites this paper
• SOX9 is a dose-dependent metastatic fate determinant in melanoma

  2019cites this paper
• miR-30c Impedes Glioblastoma Cell Proliferation and Migration by Targeting SOX9

  2019cites this paper
• Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

  2019cites this paper
• Role of miR-613 as a tumor suppressor in glioma cells by targeting SOX9

  2018cites this paper
• FOXO1 reduces tumorsphere formation capacity via reciprocal down-regulation of LGR5 in gastric cancer cells

  2018cites this paper
• SOX in development and disease

  2018cites this paper
• 5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma

  2018cites this paper
• Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness

  2017cites this paper
• FOXO1 reduces tumorsphere formation capacity and has crosstalk with LGR5 signaling in gastric cancer cells.

  2017cites this paper
• Overexpression of MicroRNA-216a Suppresses Proliferation, Migration, and Invasion of Glioma Cells by Targeting Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 5.

  2017cites this paper
• Modeling glioblastoma heterogeneity to decipher its biology

  2016cites this paper
• Stratification and therapeutic potential of PML in metastatic breast cancer

  2016cites this paper
• miR-206 inhibits non small cell lung cancer cell proliferation and invasion by targeting SOX9.

  2015cites this paper