New and rapid pulse sequences for two-dimensional D-T1 correlation measurements.

Longitudinal relaxation time (T1), transverse relaxation time (T2) and diffusion coefficient (D) values have been widely used for the characterizations of materials using low field Time Domain Nuclear Magnetic Resonance (TD-NMR). Each parameter can be determined using one-dimensional techniques or their values and correlations by multi-dimensional experiments such as T1-T2, D-T2, and T1-D-T2. In this work, we studied four D-T1 sequences for TD-NMR combining Stejskal-Tanner Pulse Gradient Spin Echo (PGSE) diffusion measurement with Inversion-Recovery (IR), Saturation-Recovery (SR), Small-Angle Continuous Wave Free Precession (CWFP-T1) and Small-Angle Flip-Flop (SAFF) for T1 measurement. The results show that rapid D-T1 measurements can be obtained with single shot CWFP-T1 and SAFF sequences. The two sequences were two and eight time fast than sequences based on SR and IR, respectively. Although the two fast sequences yield low signal-to-noise ratio signal, they can be as fast as the traditional D-T2 experiment, or even faster, because it is not necessary to wait a recycle delay of 5 T1. Another advantage of the CWFP-T1 and SAFF methods, when compared to the one based on SR or CPMG (for D-T2) are the low specific absorption rate (SAR) of these sequences due the low flip angles in the sequences, that reduces the sample heating problem. These sequences were initially studied using phantom samples. They also were used to study plant tissues to observe the anisotropic diffusion in asparagus. Therefore, they can be useful methods for practical application in TD-NMR.

• Publication year

  2020

• Venue

  Journal of magnetic resonance (San Diego, Calif. 1997 : Print)

• Publication date

  2020-05-11

• Fields of study

  Medicine, Materials Science, Physics

• Identifiers
  DOI 10.1016/j.jmr.2020.106749PMID 32438311
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Single‐shot measurement of solids and liquids T1 values by a small‐angle flip‐flop pulse sequence

  2019cited by this paper
• A novel pulse sequence and inversion algorithm of three-dimensional low field NMR technique in unconventional resources.

  2019cited by this paper
• T1-D-T2 correlation of porous media with compressed sensing at low-field NMR.

  2019cited by this paper
• Using T1 as a direct detection dimension in two-dimensional time-domain NMR experiments using CWFP regime.

  2019cited by this paper
• Direct NMR T1 distribution measurement without using ill-posed fitting methods.

  2019cited by this paper
• Noninvasive, Nondestructive Measurement of Tomato Concentrate Spoilage in Large-Volume Aseptic Packages.

  2019cited by this paper
• Physical and numerical phantoms for the validation of brain microstructural MRI: A cookbook

  2018cited by this paper
• Simultaneous acquisition for T2-T2 Exchange and T1-T2 correlation NMR experiments.

  2018cited by this paper
• Local T1-T2 distribution measurements in porous media.

  2018cited by this paper
• Towards clinically feasible relaxation-diffusion correlation MRI using MADCO.

  2017cited by this paper
• Rapid and simple determination of T1 relaxation times in time-domain NMR by Continuous Wave Free Precession sequence.

  2016cited by this paper
• Use of marginal distributions constrained optimization (MADCO) for accelerated 2D MRI relaxometry and diffusometry.

  2016cited by this paper
• On resonance phase alternated CWFP sequences for rapid and simultaneous measurement of relaxation times.

  2015cited by this paper
• Comparative study of inversion methods of three-dimensional NMR and sensitivity to fluids

  2014cited by this paper
• Multiple‐echo diffusion tensor acquisition technique (MEDITATE) on a 3T clinical scanner

  2013cited by this paper
• Rapid analyses of oil and fat content in agri‐food products using continuous wave free precession time domain NMR

  2011cited by this paper
• Time domain NMR applied to food products

  2010cited by this paper
• Rapid encoding of T(1) with spectral resolution in n-dimensional relaxation correlations.

  2008cited by this paper
• Effects of restricted diffusion in a biological phantom: a q-space diffusion MRI study of asparagus stems at a 3T clinical scanner

  2007cited by this paper
• Validation of NMR relaxation exchange time measurements in porous media.

  2007cited by this paper
• Quantitative characterization of food products by two-dimensional D-T2 and T1-T2 distribution functions in a static gradient.

  2006cited by this paper
• A global inversion method for multi-dimensional NMR logging.

  2005cited by this paper
• Use of the second dimension in PGSE NMR studies of porous media.

  2003cited by this paper
• The diffusion-spin relaxation time distribution function as an experimental probe to characterize fluid mixtures in porous media

  2002cited by this paper
• T(1)--T(2) correlation spectra obtained using a fast two-dimensional Laplace inversion.

  2002cited by this paper
• Quantitative measurement of two-dimensional distribution functions of diffusion and relaxation in grossly inhomogeneous fields.

  2002cited by this paper
• Echo planar magnetic resonance imaging of anisotropic diffusion in asparagus stems

  2001cited by this paper
• An introduction to the history of NMR well logging

  2001cited by this paper
• Well logging overview

  2001cited by this paper
• The early days of NMR in the Southwest

  2001cited by this paper
• Radiofrequency Energy‐Induced Heating During MR Procedures: A Review

  2000cited by this paper
• An Improved Diffusion-Ordered Spectroscopy Experiment Incorporating Bipolar-Gradient Pulses

  1995cited by this paper
• Quantitative Two‐Dimensional time Correlation Relaxometry

  1991cited by this paper
• A modified pulsed gradient technique for measuring diffusion in the presence of large background gradients

  1980cited by this paper
• Use of the Stimulated Echo in NMR Diffusion Studies

  1970cited by this paper
• Spin diffusion measurements : spin echoes in the presence of a time-dependent field gradient

  1965cited by this paper

• NMR spectroscopy: A versatile tool for xanthan gum research

  2026cites this paper
• Effects of Salt Stress on Seed Vigor and Water Migration in Adzuki Beans

  2025cites this paper
• Maximum-entropy and subspace methods for high-resolution relaxation-diffusion distribution estimation

  2025cites this paper
• NMR studies on mechanically oscillating samples under magnetic field gradients

  2023cites this paper
• Smooth deconvolution of low-field NMR signals.

  2023cites this paper
• Noninvasive Analyses of Food Products Using Low-field Time-domain NMR: A Review of Relaxometry Methods

  2022cites this paper
• Noninvasive Analyses of Food Products Using Low-field Time-domain NMR: A Review of Relaxometry Methods

  2022cites this paper
• Use of Time Domain Nuclear Magnetic Resonance Relaxometry to Monitor the Effect of Magnetic Field on the Copper Corrosion Rate in Real Time

  2022cites this paper
• STEADY-STATE FREE PRECESSION SEQUENCES FOR HIGH AND LOW FIELD NMR SPECTROSCOPY IN SOLUTION: CHALLENGES AND OPPORTUNITIES

  2022cites this paper
• A benchtop single-sided magnet with NMR well-logging tool specifications - Examples of application.

  2021cites this paper
• Comparison of experimental times in T1-D and D-T2 correlation experiments in single-sided NMR.

  2021cites this paper
• Recent 1D and 2D TD–NMR Pulse Sequences for Plant Science

  2021influential citation