Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors

Yi Zhou,Huiyan Sun,Ying Xu

Published 2020 in National Science Review

ABSTRACT

Summary Extensive changes in cellular metabolisms have been observed in cancer. They are probably induced by the same intracellular stressor, persistent off-balance in intracellular pH across possibly all adult cancers. It is these altered metabolisms that gives rise to a variety of cancerous behaviors such as continuous cell division, metastasis and drug resistance.

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