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Paediatric desmoplastic medulloblastoma – Surgical treatment, adjuvant therapy, outcome survival (case series study)

R. Hussein,M. Al-Jumaily,R. Hamed,A. Albayati

Published 2020 in Unknown venue

ABSTRACT

background. Desmoplastic medulloblastoma is a common adult cerebellar tumor. It has better than classic medulloblastoma outcome. This is a case series study followed up the cases of paediatric desmoplastic medulloblastoma and their treatment outcome and prognosis. Aim of study. Evaluation of the management and outcome survival, of this uncommon paediatric desmoplastic variety of medulloblastoma. Methods. 20 paediatric patients of desmoplastic medulloblastoma were collected between 2008 and 2017; 12 were males and 8 were females. All the cases were treated firstly for hydrocephalus followed by craniotomy and tumor resection. results. The children were treated medically and surgically; the desmoplastic variant of medulloblastoma demonstrated better than classic medulloblastoma outcome. Median follow-up was 24 months. The younger the child, the better the outcome. 4 patients died from recurrent medulloblastoma. Bad outcomes were in recurrent and disseminated medulloblastomas. conclusions. Surgical resection followed by chemotherapy and/or radiotherapy give better outcome in desmoplastic medulloblastoma patients comparing with the classical medulloblastoma.

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