Donor double‐negative Treg promote allogeneic mixed chimerism and tolerance

No abstract is available for this paper.

• Publication year

  2007

• Venue

  European Journal of Immunology

• Publication date

  2007-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/eji.200737408PMID 18000953
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.

  2007cited by this paper
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• Do NK-cell receptors and alloreactivity affect solid organ transplantation?

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• The changing role of natural killer cells in solid organ rejection and tolerance.

  2006cited by this paper
• Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells.

  2005cited by this paper
• Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation.

  2005cited by this paper
• Isolation and characterization of human antigen-specific TCRαβ+ CD4-CD8- double-negative regulatory T cells

  2005cited by this paper
• CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

  2005cited by this paper
• Mechanisms of suppression by suppressor T cells

  2005cited by this paper
• NK Cells Can Trigger Allograft Vasculopathy: The Role of Hybrid Resistance in Solid Organ Allografts1

  2005cited by this paper
• Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

  2005cited by this paper
• Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD.

  2005cited by this paper
• Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance.

  2005cited by this paper
• Mechanisms of suppression by suppressor T cells

  2005cited by this paper
• Cells during Acute Graft-versus-host Disease Regulatory T + Cd25 + Critical Role for Ccr5 in the Function of Donor Cd4

  2005cited by this paper
• Chimeric Donor Cells Play an Active Role in Both Induction and Maintenance Phases of Transplantation Tolerance Induced by Mixed Chimerism1

  2004cited by this paper
• Mixed chimerism and transplantation tolerance.

  2004cited by this paper
• Anti-NK cell treatment induces stable mixed chimerism in MHC-mismatched, T cell-depleted, nonmyeloablative bone marrow transplantation.

  2004cited by this paper
• Production of Donor T Cells Is Critical for Induction of Donor-Specific Tolerance and Maintenance of Chimerism1

  2004cited by this paper
• A Unique Population of Extrathymically Derived αβTCR+CD4−CD8− T Cells with Regulatory Functions Dominates the Mouse Female Genital Tract 1

  2003cited by this paper
• CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

  2003cited by this paper
• B220+ Double-Negative T Cells Suppress Polyclonal T Cell Activation by a Fas-Independent Mechanism That Involves Inhibition of IL-2 Production

  2003cited by this paper
• The JAM-assay: optimized conditions to determine death-receptor-mediated apoptosis.

  2003cited by this paper
• Non‐Classical Pathways of Cell‐Mediated Allograft Rejection: New Challenges for Tolerance Induction?

  2003cited by this paper
• NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade.

  2003cited by this paper
• Inhibition of Graft-Versus-Host Disease by Double-Negative Regulatory T Cells1

  2003cited by this paper
• A Comparative Study of the JAM Test and 51Cr‐Release Assay to Assess the Cytotoxicity of Dendritic Cells on Hematopoietic Tumor Cells

  2003cited by this paper
• CD4+CD25+ T Cells Lyse Antigen-Presenting B Cells by Fas-Fas Ligand Interaction in an Epitope-Specific Manner 1

  2003cited by this paper
• Modulation of tryptophan catabolism by regulatory T cells

  2003cited by this paper
• NK Cell Tolerance in Mixed Allogeneic Chimeras1

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• Anergic T cells exert antigen-independent inhibition of cell-cell interactions via chemokine metabolism.

  2003cited by this paper
• A unique population of extrathymically derived alpha beta TCR+CD4-CD8- T cells with regulatory functions dominates the mouse female genital tract.

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• Infusion of in vitro-generated DN T regulatory cells induces permanent cardiac allograft survival in mice.

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• Ly‐6A is critical for the function of double negative regulatory T cells

  2002cited by this paper
• CD4+CD25+ Immunoregulatory T Cells

  2002cited by this paper
• Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cells.

  2002cited by this paper
• Mixed chimerism and transplantation tolerance.

  2001cited by this paper
• Critical role of NK but not NKT cells in acute rejection of parental bone marrow cells in F1 hybrid mice

  2001cited by this paper
• Mixed chimerism and transplant tolerance.

  2001cited by this paper
• Dissociation of Hemopoietic Chimerism and Allograft Tolerance After Allogeneic Bone Marrow Transplantation1

  2001cited by this paper
• Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies

  2001cited by this paper
• CD4(-)CD8(-) regulatory T cells implicated in preventing graft-versus-host and promoting graft-versus-leukemia responses.

  2001cited by this paper
• TCR/Self-Antigen Interactions Drive Double-Negative T Cell Peripheral Expansion and Differentiation into Suppressor Cells1

  2001cited by this paper
• Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

  2000cited by this paper
• Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism.

  1999cited by this paper
• Association of natural killer cell depletion with induction of mixed chimerism and allograft tolerance in non-human primates.

  1999cited by this paper
• Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients.

  1999cited by this paper
• Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen.

  1998cited by this paper
• Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys.

  1997cited by this paper
• Microchimerism and rejection in clinical transplantation.

  1997cited by this paper
• Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

  1997cited by this paper
• Three years of follow-up of bone marrow-augmented organ transplant recipients: the impact on donor-specific immune modulation.

  1997cited by this paper
• The potential role of NK cells in the separation of graft‐versus‐tumor effects from graft‐versus‐host disease after allogeneic bone marrow transplantation

  1997cited by this paper
• High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing.

  1997cited by this paper
• Mechanism for cotolerance in nonlethally conditioned mixed chimeras: negative selection of the Vbeta T-cell receptor repertoire by both host and donor bone marrow-derived cells.

  1996cited by this paper
• Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach.

  1996cited by this paper
• Development, stability, and clinical correlations of allogeneic microchimerism after solid organ transplantation.

  1996cited by this paper
• Augmentation of chimerism in whole organ recipients by simultaneous infusion of donor bone marrow cells.

  1995cited by this paper
• Regulation of NK cell functions by TGF-beta 1.

  1995cited by this paper
• Enhancement of donor cell chimerism in whole organ allograft recipients by adjuvant bone marrow transplantation.

  1995cited by this paper
• Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen.

  1994cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1987cited by this paper
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  1986cited by this paper
• Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance

  1985cited by this paper
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  1983cited by this paper
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